A new tool, LipidCruncher, aims to simplify one of the most complicated parts of research on lipids: making sense of large, messy datasets. By guiding researchers through each step, the platform helps make results easier to share and reproduce. HHMI’s Janelia Research Campus is launching a decade-long scientific effort to pursue two coequal goals: understanding how the brain generates complex behavior, and developing a new mode of scientific discovery in which biologists and AI work together as partners in discovery.Freeman Hrabowski Scholar Corina Amor Vegas adapted CAR-T cells, a cancer immunotherapy approach, to help aging immune systems relearn how to clear damaging senescent cells.HHMI Gilliam Fellows are PhD students and postdoctoral researchers who are pursuing innovative science that’s helping shape their careers. These highlights from Hadassah Mendez-Vazquez and Angel Garcia offer a glimpse into the breadth of their work, showcasing the wide-ranging questions they’re exploring and the discoveries they’re beginning to uncover. The immersive summer research program pairs talented undergraduates from 109 institutions across 36 states and territories with leading HHMI scientists.By examining what happens in the brain during REM sleep, HHMI Investigator Massimo Scanziani and his team are uncovering how the brain dreams up scenarios without any input from the outside world.
This story is part of a series exploring sleep research at HHMI.Researchers in the Dudman Lab at HHMI’s Janelia Research Campus found that learning happens faster when there’s a bigger payoff for success, potentially changing how neuroscientists think about learning and how they study it. What if scientists could watch a dozen proteins at work inside a cell at the same time? A new AI@HHMI project combines AI-driven protein design with bright dyes to build probes that could make that possible.
This story is part of a series exploring AI@HHMI projects.HHMI Gilliam Fellows are PhD students and postdoctoral researchers who are pursuing innovative science that’s helping shape their careers. These highlights from Izaiah Ornelas and Destiny Tiburcio offer a glimpse into the breadth of their work, showcasing the wide-ranging questions they’re exploring and the discoveries they’re beginning to uncover. HHMI Freeman Hrabowski Scholar Siniša Hrvatin studies how animals hibernate — and what that state reveals about the biology of survival and aging.