Autonomic dysfunction
| Subclass of | autonomic nervous system disease |
|---|---|
| Has effect | medically unexplained physical symptom |
| Health specialty | neurology |
Dysautonomia, autonomic failure, anaa autonomic dysfunction be a condition insyd wich de autonomic nervous system (ANS) no dey work properly. Dis condition fi affect de functioning of de heart, bladder, intestines, sweat glands, pupils, den blood vessels. Dysautonomia get chaw causes, no be all of wich fi be classified as neuropathic.[1] A number of conditions fi feature dysautonomia, such as Parkinson's disease, Long COVID, multiple system atrophy, dementia with Lewy bodies,[2] Ehlers–Danlos syndromes,[3] autoimmune autonomic ganglionopathy den autonomic neuropathy,[4] HIV/AIDS,[5] mitochondrial cytopathy,[6] pure autonomic failure, autism, den postural orthostatic tachycardia syndrome.[7]
Diagnosis be made by functional testing of de ANS, wey dey focus on de affected organ system. Investigations fi be performed to identify underlying disease processes wey fi lead to de development of symptoms anaa autonomic neuropathy. Symptomatic treatment be available give chaw symptoms dem associate plus dysautonomia, den sam disease processes fi be directly treated. Depending on de severity of de dysfunction, dysautonomia fi range from being nearly symptomless den transient to disabling den/anaa life-threatening.[8]
References
[edit | edit source]- ↑ "Dysautonomia". NINDS. Archived from the original on 2016-12-02. Retrieved 2012-04-03.
- ↑ Castori, Marco; Voermans, Nicol C. (2014-10-06). "Neurological manifestations of Ehlers-Danlos syndrome(s): A review". Iranian Journal of Neurology. 13 (4): 190–208. ISSN 2008-384X. PMC 4300794. PMID 25632331.
- ↑ Castori M, Voermans NC (October 2014). "Neurological manifestations of Ehlers-Danlos syndrome(s): A review". Iranian Journal of Neurology. 13 (4): 190–208. PMC 4300794. PMID 25632331.
- ↑ Imamura M, Mukaino A, Takamatsu K, Tsuboi H, Higuchi O, Nakamura H, Abe S, Ando Y, Matsuo H, Nakamura T, Sumida T, Kawakami A, Nakane S (February 2020). "Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases". Int J Mol Sci (Review). 21 (4): 1332. doi:10.3390/ijms21041332. PMC 7073227. PMID 32079137.
- ↑ McIntosh RC (August 2016). "A meta-analysis of HIV and heart rate variability in the era of antiretroviral therapy". Clin Auton Res (Review). 26 (4): 287–94. doi:10.1007/s10286-016-0366-6. PMID 27395409. S2CID 20256879.
- ↑ Kanjwal, Khalil; Karabin, Beverly; Kanjwal, Yousuf; Saeed, Bilal; Grubb, Blair P. (October 2010). "Autonomic dysfunction presenting as orthostatic intolerance in patients suffering from mitochondrial cytopathy". Clinical Cardiology. 33 (10): 626–629. doi:10.1002/clc.20805. ISSN 1932-8737. PMC 6653231. PMID 20960537.
- ↑ Peltier AC (June 2024). "Autonomic Dysfunction from Diagnosis to Treatment". Prim Care. 51 (2): 359–373. doi:10.1016/j.pop.2024.02.006. PMID 38692780.
- ↑ Iodice V, Kimpinski K, Vernino S, Sandroni P, Fealey RD, Low PA (June 2009). "Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopathy". Neurology. 72 (23): 2002–8. doi:10.1212/WNL.0b013e3181a92b52. PMC 2837591. PMID 19506222.