PinnedMedChemExpress·Jul 2, 2025Overcoming the ‘Undruggable’: How PROTACs Are Expanding Therapeutic FrontiersIn recent years, PROteolysis TArgeting Chimeras (PROTACs) have emerged as a transformative approach that leverages the cell’s endogenous…A response icon6A response icon6
MedChemExpress·6h agoCan Gentle Laser Heat Prevent Blindness? A New Approach to Dry AMD Is Turning HeadsAge-related macular degeneration (AMD) remains one of the leading causes of irreversible vision loss worldwide, especially in aging…
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MedChemExpress·6d agoNb-PROTAC Enables a Broad-Spectrum Breakthrough Against Influenza AInfluenza A viruses remain a persistent global health challenge, driven by rapid mutation and the frequent emergence of drug resistance…
MedChemExpress·May 15PMOS: Why the Renaming of PCOS Marks a Turning Point in Women’s HealthFor decades, Polycystic Ovary Syndrome (PCOS) has been one of the most misunderstood conditions in women’s health. Despite affecting more…
MedChemExpress·May 15The Dual Role of Cellular Senescence in Cancer: Mechanisms, Microenvironment, and TherapeuticsCellular senescence, originally defined as an irreversible cell-cycle arrest program, suppresses tumorigenesis by limiting the…
MedChemExpress·May 9Hantavirus Outbreak: A Rare Virus, a Global Reminder of Zoonotic ThreatsHantavirus infection is a zoonotic viral disease transmitted from rodents to humans. While relatively rare, it can cause severe clinical…
MedChemExpress·May 9Tumor Organoid-Immune Cell Co-Culture Models: Advances, Applications, and Future DirectionsTumor organoids, as three-dimensional (3D) in vitro culture models, have emerged as powerful tools in cancer research and drug screening…
MedChemExpress·Apr 20ADCs Are More Than Cytotoxic Agents: Unlocking Immune Synergy in Cancer TherapyAntibody-drug conjugates (ADCs) have emerged as a transformative modality in oncology by combining the target specificity of antibodies…
![Figure 1. Common TPD technologies[1].](https://miro.medium.com/v2/resize:fill:160:106/1*N4Q-p4w85Kh_gFSktRRCOQ.png)
![Figure 1. Common TPD technologies[1].](https://miro.medium.com/v2/resize:fill:320:214/1*N4Q-p4w85Kh_gFSktRRCOQ.png)
