Modulight news & articles

Published in: Cytometry Part B: Clinical Cytometry Authors: Alice Yue, Ryan R. Brinkman, Veronica Nash, Fabian Junker, Goce Bogdanoski, Anagha Divekar, Aaron Tyznik, Josef Spidlen, Wolfgang Kern, Jordi Petriz, Kaska Wloka, Kamila Czechowska  

Published in: Cancer Immunology, Immunotherapy Authors: Motofumi Suzuki, Aki Furusawa, Hiroshi Yamamoto, Makoto Kano, Miyu Kano, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi  

Published in: Annals of Medicine Authors: Aki Furusawa ,Seiichiro Takao, Motofumi Suzuki, Makoto Kano, Hiroshi Yamamoto, Miyu Kano, Peter Choyke, Hisataka Kobayashi  

Published in: Langmuir Authors: Sumiao Pang, Rebecca J. Johnson, Nikhil Pandey, Anshika Kapur, Pavlos Anastasiadis, Pranjali Kanvinde, Emylee McFarland, Jeffrey A. Winkles, Graeme F. Woodworth, Anthony J. Kim, Huang Chiao Huang  

Published in: npj Acoustics Authors: Andrew Langley, Allison Sweeney, Ronak T. Shethia, Brooke Bednarke, Faizah Wulandana, Marvin Xavierselvan, Srivalleesha Mallidi  

Published in: Bioengineering & Translational Medicine Authors: Chen-Hua Ma, Jeffrey Yang, John A. Quinlan, Kathryn McNaughton, Michele L. Kaluzienski, Tessa Hauser, Matthew F. Starost, Jenna L. Mueller, Huang-Chiao Huang  

Age-related Macular Degeneration (AMD) Age-related Macular Degeneration (AMD) is a disease causing choroidal neovascularization (CNV) and consequent irreversible damage in the macula. AMD is classified into dry (atrophic) and wet (exudative) forms, with the latter causing faster vision loss and being the leading cause of blindness in people over 65. Introduction to AMD Age-related Macular [...]

Next generation flow cytometry Lasers have been historically the key light sources utilized in flow cytometry due to their ability to deliver the precise amount of energy needed to trigger the Stokes shift, which is the key phenomena underlying flow cytometry operation. For the same reason lasers and optical system in general are referred to [...]

Background Photobiomodulation with low-level laser or light therapy is an effective treatment for pain. It has various effects, such as analgesic (pain-relieving) effects, anti-inflammatory effects, tissue regeneration promoting effects, and wound healing effects. Photobiomodulation can be used to relief both acute and chronic pain and has the advantage of being noninvasive and safe. Earlier studies […]

Background The proper delivery and release of therapeutic drugs to a specific site or cell type is one of the main challenges in the treatment of diseases. Liposomes, which are vesicles composed of lipids, serve as carriers for drug delivery thanks to their long circulation time. This results to reduced toxicity in healthy tissues and […]

Deadliest cancer Precision with photoactivation Photoimmunotherapy with ML7710 offers a clinical therapeutic option for NSCLC patients even with advanced disease stage. Besides laser light, this therapy involves photoactivated drug, which can be activated precisely at the tumor site with laser fibers, hence minimizing drug effects to healthy tissues. Smaller invasiveness compared to surgery can enable […]

Introduction to DRB lasers Distributed Bragg Reflector (DBR) laser diodes are a class of single-frequency monolithic semiconductor lasers. Monolithic semiconductor lasers in general are small in size, mechanically robust, and have good power conversion efficiency. They also provide opportunities for hybrid integration with photonic integrated circuits (PICs). This application note provides an overview of DBR [...]

Modulight Spotlights: LASER-SHARP RESEARCH – January 2026 The highlight of the month goes to teams of researchers led by Prof. Imran Rizvi at University of North Carolina at Chapel Hill. Their latest publication shows that certain light-activated therapy with BPD photosensitizer and ML6600 laser can induce ferroptosis-like cell death, including formation of lipid peroxides, in [...]

Deeksha Sankepalle and the group at Tufts University, USA developed an advanced multi-wavelength photoacoustic imaging system. It integrates a pulsed, tunable laser with an ultrasound acquisition platform to provide functional 3D imaging. The system enables real-time, non-invasive, high-resolution imaging of tumor vasculature by tracking oxygen saturation in the tumor.

Modulight Spotlights: LASER-SHARP RESEARCH – November 2025 We are delighted to highlight new exciting study by Rahman et al. from Dr. Huang-Chiao Huang’s lab at University of Maryland. Multidrug resistance remains a significant barrier to successful chemotherapy outcomes for cancer patients, often caused by active pumping of chemotherapeutics outside of cancer cells. Hence, the team [...]

This month we are highlighting exciting findings by S. Takao et al. from Hisataka Kobayashi’s lab at the National Cancer Institute, NIH. Published in Cancer Letters, the study shows that near-infrared photoimmunotherapy can destroy cancer cells by targeting intercellular adhesion molecule-1.

Published in journal Cancer Medicine, the study shows that the therapeutic effect of photoimmunotherapy is highly dependent on the used light irradiation conditions. Application of the ML7710 medical laser at different durations and powers resulted in highest anti-tumor effect with increased light dose but lowering fluence rate below what is currently used in clinic.

Laser-sharp research of the month is by Furusawa et al. at Center for Cancer Research, National Cancer Institute, USA. The discovery, published in Annals of Medicine, showed the potential of photoimmunotherapy for treating breast cancer. To expand the usefulness of photoimmunotherapy outside the clinically approved head & neck indication, the new therapy targeted epithelial cell adhesion molecule in breast cancer.

Modulight announces yellow and orange laser wavelengths with several watts of output power, excellent beam quality, and unmatched flexibility. Traditionally difficult to achieve, Modulight’s VECSEL-based ML6600 series lasers now close the yellow-orange gap between 570 and 630 nm.

A new addition to Modulight’s Fiber Laser Portfolio, ML6615, is a Mid-IR laser with 2.7–3 µm wavelength. The ML6615 laser is well-suited for soft tissue and dental treatments, and cutting, welding, and micro-machining polymers and certain glasses and ceramics. In aerospace and remote sensing, the system opens possibilities for specialized applications such as humidity and remote sensing tasks. ML6615 delivers up to 10 W of output power, supportiong both CW and QCW operating modes.

Building on the earlier introduction of a tapered amplifier portfolio, Modulight now offers a highly stable, fiber-coupled DBR MOPA system designed for demanding applications requiring exceptional robustness and ease of integration. This DBR MOPA systems answer to the need of quantum technology, high-precision timing, sensing, and spectroscopy applications, providing 750 nm…1100 nm wavelengths and over 1 W of free-space output power.

ML6660 is Modulight’s new, spectroscopy-optimized laser platform, which is now launched with 785 nm DBR laser configuration. It offers exceptional wavelength stability and high single-mode output powers. The laser is especially well-suited for Raman spectroscopy.

Modulight’s new portfolio of single-frequency DBR and DFB lasers and high-power tapered amplifiers is targeted for quantum sensing and quantum computing applications. Additionally, these products are used in magnetometers, spectroscopy, atomic clocks, metrology, and manipulating atoms.

Introducing Modulight’s Versatile DBR Laser platform Modulight announces the launch of its latest Distributed Bragg Reflector (DBR) lasers, offering a configurable wavelength range from 630 nm to 1100 nm. These advanced lasers are designed to meet the high demands in quantum systems, quantum sensing, Raman spectroscopy, and metrology.  Key wavelengths of Modulight DBR laser platform [...]