Our Research Focus
In the Cancer Dependency Map project, we profile large panels of cell line models to capture the heterogeneity of human cancer and link the molecular and genetic alterations of the tumors to their dependencies. Within the TDA laboratory we:
Apply new functional genomics approaches and technologies to identify new ways to map vulnerabilities at scale.
Develop experimental and computational strategies to prioritize therapeutic targets from DepMap datasets.
Investigate the molecular basis of the dependencies and triage targets to drug discovery pipelines.
