For Founders.
By Founders.
For Life.

Reinventing how AI Is delivered and consumed, including the rise of Collaborative Intelligence as a Service and AI Teammates. Leading investments at Seed, Series A and Series B.

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120 IPOs

225+ M&As

$3B+ AUM

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We’re in the Collaborative Intelligence era: Where humans and Al teammates work together, elevating people’s capabilities to superhuman levels. Mayfield backs founders across the Collaborative Intelligence-as-a-Service (CaaS) stack – the new paradigm revolutionizing how generative Al is delivered and consumed.

News

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Blog
01.2026
Follow the Money: Enterprise AI’s Trillion-Dollar Moment

Why enterprise AI is a trillion-dollar opportunity and how product-led trials, ROI proof, and governance turn experimentation into scaled adoption.

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Blog
01.2026
AI’s Next Bottleneck: Why Networking Is the New Chokepoint

As AI scales across specialized silicon, idle compute breaks the economics. Networking is now the critical chokepoint in AI infrastructure.

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Blog
05.2025
Lifetime Achievement Award for Satya Nadella

Satya Nadella shares his POV on maintaining relevance and building enduring companies with Navin Chaddha at TiEcon 2025.

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Blog
10.2025
Securiti Acquired for $1.725B to Accelerate Safe Enterprise AI at Scale

The secret to building billion-dollar companies isn’t just a great idea—it’s the foundation of a long-term founder-investor relationship.

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Mayfield News
09.2024
Mayfield Allocates $100M to AI Incubator Model

Announcing Mayfield AI Garage, an EIR inspired initiative for AI Teammates.

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