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biohub
5,982 posts
biohub
@biohub
Combining frontier AI & frontier biology to help scientists cure or prevent disease
Joined June 2017
Tool development will empower scientists to move faster. @NoPriorsPod
00:00- Most of the proteins that make up life on Earth have never been studied. Not because scientists aren't curious—because the tools to explore them didn't exist. ESM Atlas is a new way in. Ask it a question in plain language and it reasons across 6.8 billion proteins to answer. Not
GIF - A world model of protein biology — what does that actually mean? @alexrives explains on @NoPriorsPod ⤵️
00:00 - biohub reposted
More than 15 years ago, a physicist had an outrageous idea. It was dismissed as impossible. Now here we are, with a device that is pure engineering madness. And it could quite literally change how we view biology. 🧵 (1/7)
- biohub reposted
"This breakthrough will be truly revolutionary if it is able to solve unique structures of small proteins, particularly those inside frozen cells," says @BerkeleyLab's Peter Ercius. @AMIposts @LindaFStewart - biohub reposted
Wow this is insanely awesome. I bet like <0.01% of X understands even remotely what this is or why it's important but this is insanely awesome.Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in
00:00 - "If you could really just look inside a cell and see the proteins that you liked, that’s the next revolution in structural cell biology. It might change everything,” says Biohub’s Bridget Carragher. Read more in @ScienceMagazine:
- The laser phase plate is leveling up cryoEM so we can see biology like never before. Learn more: bit.ly/4vIPC1U
- biohub reposted
“Before, studying structures with cryo-EM was like trying to look at paintings in a dark gallery. With Theia, it’s like the lights have been turned on for the first time.” – Holger Müller, @UCBerkeley professor and LBNL Biosciences Area faculty scientist
- biohub reposted
CryoEM has pretty low resolution, you can see things on the order of protein domains, and you need millions of particles to see individual proteins. This enables us to get an order of magnitude higher resolution, where we're able to _see_ the secondary structures in a singleTogether with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in00:00
