Impact

Articles

02 2025

1

The senotherapeutic potential of phytochemicals for age-related intestinal disease

Célia Maria Costa, Sílvia Santos Pedrosa, James L. Kirkland, Flávio Reis, Ana Raquel Madureira, Ageing Research Reviews, Volume 104, (2025) 102619, https://doi.org/10.1016/j.arr.2024.102619.

03 2025

1

miRNA-642a-3p protects β cells from glucolipotoxicity

Pinhanços, Sandra Sofia et al. (2025) Molecular Therapy Nucleic Acids, Volume 36, Issue 2; DOI: 10.1016/j.omtn.2025.102498

08 2025

2

A New Phenotype-Genotype Correlation for FIG4 and Parkinson’s Disease

Boura, I., Mitsias, P., Erimaki, S., Papadaki, E. and Spanaki, C. (2026). Mov Disord Clin Pract. https://doi.org/10.1002/mdc3.70319

06 2025

1

Incidence, prevalence and mortality of Parkinson’s disease in Greece

Makris, G., Samoli, E., Chlouverakis, G. et al. Neurol Sci 46, 5027–5034 (2025). https://doi.org/10.1007/s10072-025-08297-2

08 2024

1

Spermidine is essential for fasting-mediated autophagy and longevity

Hofer, S.J., Daskalaki, I., Bergmann, M. et al. Nat Cell Biol 26, 1571–1584 (2024). https://doi.org/10.1038/s41556-024-01468-x

Advanced Training

02 2026

Advanced Course

One Health: a metabolic approach from cells to society

One Health: a metabolic approach from cells to society. PhD course open to the PhD program in Health Sciences, PhD program in Cell Biology and Experimental Biomedicine, PhD program in Biosciences. University of Coimbra; May 2-6, 2026.

05 2025

Course

HOST-MICROBIOME METABOLIC CROSS TALK IN AGING

Seminar: Host-microbiome cross talk in aging, Clara Correia-Melo, Leibniz Institute of Aging, Jena, Germany. Faculty of Medicine, University of Coimbra, May 13, 2025

02 2025

Course

Spatio-temporal regulation of adult neural stem cells by microenvironment

Seminar: Spatio-temporal regulation of adult neural stem cells by microenvironment, Armen Sagathelyan, University of Otawa, Canada. Faculty of Medicine, University of Coimbra, February 27, 2025

05 2025

School

ERASMUS+ Blended Intensive Program on Cognitive Disorders

The University of Crete (main organizer), University of Coimbra, University of Valencia and Acibadem University organised the ERASMUS + Blended Intensive Course on Cognitive Disorders. CHAngeing partners University of Crete and University of Coimbra supported the collaboration through a quadruple helix perspective and explored the scientific links between Healthy Lifestyles supported by Mediterranean diet Culture and Brain Health. The physical component of the course took place in Heraklion, May 5-9, 2025.

12 2023

School

EIT Health Ageing PhD School Annual Retreat

The Annual Retreat of EIT Health Ageing PhD School took place in Coimbra, December 4-7, 2023. This event enclosed close collaboration and synergies with CHAngeing partners, including students from University of Coimbra and University of Crete, and also lecturers from the University of Coimbra, FORTH and Instituto Pedro Nunes.

Twinning & Collaboration

11 2025

Conferences

IV ASPIC–ASEICA International Meeting in Santiago de Compostela – Spain

From November 20-21, Liliana Santos (PhD) participated at the IV ASPIC–ASEICA International Meeting in Santiago de Compostela - Spain. Dr. Santos presented a poster titled: “ENPP1 Inhibition Delays Brain Metastasis Onset by Preserving Blood-Brain Barrier Integrity and Restoring Antitumor Immunity” Proud moment for our team to share their exciting research and proudly representing our group in such an inspiring environment dedicated to advancing oncology science!

12 2025

Matchmaking

Ageing@UC and CRUSOE Meeting_Building Quadruple Helix Networks

CHAngeing project is working with the Researcher's community of the University of Coimbra (Ageing@UC) and CRUSOE network to build the thematic group on "Healthy Living, Ageing and Longevity". This collaborative effort aims at reinforcing collaboration and synergies between different research groups and institutions in the Nordwest of Iberian Peninsula. Coimbra, December 9, 2025.

10 2025

Conferences

Brain Ageing and Alzheimer’s Disease_Coimbra

The Portuguese Society for Neuroscience and the Neurology Portuguese Society joined efforts with CHAngeing to organize the meeting of the working group on "Brain Ageing and Alzheimer's Disease", Colégio da Santíssima Trindade, Coimbra, 24 & 25 November 2025. Ioannis Zaganas was invited key note lecturer on Brain Ageing and Lifestyles.

07 2025

Matchmaking

CHAngeing is a member of Excellence Hubs Community

CHAngeing, represented by George Papamichail, participated in the Excellence Hubs Community Meeting, in Ioannina, Greece, July 2, 2025

01 2024

Collaborative Ideas

First year of CHAngeing project; Coimbra-Crete synergies to build next implementation activities

João Malva, coordinator of CHAngeing visited the team in FORTH and University of Crete to reinforce contacts and build synergies.

Entrepreneur Training

Entrepreneurial Program

The CHAngeing Entrepreneurial programme is a 4-intensive week training designed to empower participants with the essential skills, knowledge, and connections to thrive in the fast-paced healthcare industry. This programme offers a dynamic blend of interactive workshops, expert-led mentoring sessions, and hands-on group projects, diving deep into key aspects of innovation and entrepreneurship, specifically tailored to the unique challenges and opportunities within the healthcare sector. Key Takeaways: • Entrepreneurship Concepts: Equip participants with the fundamentals of entrepreneurship, including needs assessment, value proposition, clinical validation, stakeholder engagement, and marketing for health startups. • Finance and Investment Programs in Health: Gain a solid understanding of finance strategies and investment opportunities specific to healthcare ventures. • Intellectual Property and Pitching: Learn how to manage intellectual property and develop the ability to pitch healthcare innovations to potential investors, stakeholders, and partners. • Expert Guidance and Mentorship: Receive valuable insights from seasoned professionals in healthcare innovation, helping navigate real-world challenges. • Multidisciplinary Collaboration: Work in diverse, multidisciplinary teams with peers from across the EU, fostering cross-cultural collaboration and innovative problem-solving in a real-world context. • Networking and Partnership Building: Expand your professional network by connecting with investors, healthcare experts, and fellow innovators, identifying opportunities for collaboration and growth. Throughout the programme, they will work in diverse, multidisciplinary teams with peers from across the EU, fostering a rich environment for cross-cultural collaboration and innovation. By the end of the course, participants will have built a solid foundation in healthcare entrepreneurship, equipping them to lead transformative innovations in the bio and health ecosystem, to succeed in a highly competitive market, and to meet the growing demands of an ageing society. To Register in the Program please Press "Know More"

START’Ship studentxCEO Hackathon

START'Ship ERASMUS+ project in synergies with CHAngeing Excellence Hubs implemented a StudentxCEO Hackathon. 16 students developed innovative solutions for business challenges raised by 5 CEOs. University of Coimbra, May 21 & 22, 2025

POPRI_International EUSAIR youth business model competition

FORTH STEP-C and Primorski Technological Park, Slovenia, co-organized the International Business Model youth competition POPRI under the scope of EUSAIR Greek Presidency 2024-2025. The vent took place in Georgioupolis, Crete, May 6-7 2025. João Malva (CHAngeing coordinator) acted as a member of the jury for University Students competition.

Project Deliverables