Welcome to Creatine.Wiki

The Ultimate Creatine Knowledge Base
Creatine Facts
A naturally occuring compound synthesized from amino acids and found in muscle cells.
Natural Sources
Supplementation
Loading Phase 20g/day × 5 days
Maintenance 3-5g/day
Benefits
Performance
Other
Side Effects
Severe
Mild
Contraindications
Not for people with:
  • Kidney disease
  • High blood pressure
  • Liver disease
Regulatory Status
Legal and permitted by all major sports organizations
Considerations for Populations
Availability
Over-the-counter
Common Forms

Creatine Basics

Bodybuilder Flexing Muscles

Creatine is a naturally occurring compound found in muscle cells that plays a vital role in energy metabolism and muscle function. While the human body produces a small amount of creatine naturally, and another small amount is obtained through diet (primarily from meat and fish), supplementation has become increasingly popular among athletes and fitness enthusiasts.

Creatine supplementation, most commonly in the form of creatine monohydrate, has been extensively studied and shown to improve muscle strength, power output, and exercise performance, particularly in high-intensity, short-duration activities. Research has consistently demonstrated that supplementation can significantly increase muscle creatine concentrations.

Beyond its well-known benefits for physical performance, emerging research suggests potential benefits for cognitive function and various medical conditions, making it a subject of continued scientific interest and investigation.

Creatine Benefits

Gym Training Session

Creatine is one of the most extensively studied supplements in sports nutrition, primarily known for its effects on athletic performance and muscle development. When combined with resistance training, it helps build lean muscle mass, enhance strength, and improve high-intensity exercise performance by supporting the body's energy production systems.

Creatine has less pronounced or mixed results when it comes to lower output activies, such as moderate cardio or endurance sports.

Beyond athletics, creatine has emerged as a potentially beneficial compound with wide-ranging effects on human health. Research continues into benefits for mental wellness, cognitive function, anti-aging, various medical conditions, energy metabolism, and even skincare.

Creatine Usage

Dry Scoop Creatine

Creatine is often consumed with plain water, but can also be mixed with various liquids such as milk, fruit juices, coffee, or sports drinks. Some people like to mix creatine with carbs for potentially faster absorption. Others take it in combination with other sports supplements, or it can even be incorporated into cooked foods.

Typical usage involves an optional loading phase (about 20 grams per day for 5 days) followed by a maintenance phase (consistent 3-5 gram daily intake). For more tailored recommendations see the Creatine Calculator.

Creatine supplementation has been used by various populations, including athletes, teenagers, diabetics, and seniors. It can enhance strength and power in women and is compatible with special diets.

Creatine Side Effects

Person Walking to Restroom

Creatine is generally considered safe for healthy individuals, with research showing no adverse effects from long-term use at recommended doses.

Supplementation can cause several mild short-term side effects that vary from person to person. The most common side effects include water retention, temporary bloating, and occasional gastrointestinal discomfort. These effects are typically temporary and often manageable through proper dosing and hydration. More serious side effects are rare, and research consistently shows that creatine is highly safe.