Featured New Products
•Full Portfolio: FcγR, FcαR, FcεR, FcμR, FcRn, and More
•Exceptional Purity: Verified by PAGE, HPLC, and MALS
•Proven Bioactivity: Validated by SPR and BLI
•Ready-to-Use, Simple, Rapid, High Sensitivity & Low Background
•Supporting kinase activity detection and high-throughput inhibitor screening
•Covers all WHO-recommended Northern/Southern hemispheres strains
•Multiple antigens: HA, HA Trimer, NA, NP.
Weekly New Products
Human TL1A/TNFSF15 Protein (mFc Tag)
Human CTLA-4 Protein (His & AVI Tag), Biotinylated
Mouse S100A4 Protein (His & AVI Tag), Biotinylated
Influenza A H3N2 (A/New York/GKISBBBG87773/2025) Hemagglutinin / HA trimer Protein (His Tag)
Influenza A H3N2 (A/New York/GKISBBBG87773/2025) Neuraminidase / NA Protein (ECD, His Tag)
Rhesus IL-23 P19/IL23A Protein (hFc Tag)
Human CD14 Protein (His & AVI Tag), Biotinylated
Cynomolgus CD5 Protein (His Tag)
Comprehensive Solutions
Autoimmune Disease Research Solutions
3D Organoids Research Solutions


Kinase Drug Discovery Solutions
Solutions for Infectious Disease Research
Solutions for MSCs Therapy
ADC Development Solutions
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Autoimmune Disease Research Solutions
Comprehensive Support for Autoimmune Disease Early Diagnosis and Drug Discovery
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•Covering target proteins, cytokines and kinase targets
•High purity: Verified by HPLC
•High activity: Validated by ELISA, BLI, SPR, and cell-based assays
•Different research stages: drug discovery, preclinical, clinical research, and approved drugs
•Target proteins with high activity, purity, and batch-to-batch consistency.
3D Organoids Research Solutions
• Vast Selection • High Quality • Rigorous Quality Control
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•Cytokines designed for organoids culture: Intestinal organoid, gastric organoid, cardiac organoid...
•Examples of organoids culture
•Selected reagents for tumor organoids research: Colorectal cancer organoids, Breast cancer organoids...
•Examples of tumor organoid culture and charactertion
•Certified by ISO 9001, ISO 13485, and GMP
•Release standards refer to USP and ChP
•FDA DMF filing
•Essential cytokines and small molecules for organoid culture
•Specific markers for organoid characterization
•Videos and podcasts
•Organoid research handbook
•Latest organoid research articles
•...
Kinase Drug Discovery Solutions
Spanning Target Discovery to Compound Screening, Profiling, and Optimization
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•Kinase activity is king at SignalChem Biotech
•Highly active kinases ensure precision in screening and profiling
•Encompassing >90% of the human kinome
•Cited in 2,000+ customer publications in high impact journals
•400+ disease-associated mutants of 70+ kinases
•Covering a plethora of on-target mutations conferring acquired resistance
•Stringent quality control ensures high activity and lot-to-lot contensistency
•Proprietary production and quality control platforms
•Custom active enzymes: full-length/truncated, untagged/tagged, etc.
•Multiple biochemical and cellular assay platforms
•Reliable assays based on comprehensive validation
•Two-week turnaround time
•Custom assay development
•Assessing compound selectivity, potency, kinetics, MoA, etc.
•Supporting initial screens to hit-to-lead and lead optimization.
•Browse human kinome and search products by protein kinase family
•FDA-approved kinase inhibitors and recommended products for each target
•Case study: supporting the development of the Promega kinase selectivity profiling system
•Interactive signaling pathways
•News: Sino Biological finalizes the acquisition of SignalChem Biotech
Comprehensive Solutions for Infectious Disease Research
Support basic research and the development of vaccines, drugs, and diagnostic reagents
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•SARS-CoV-2, influenza, Mpox, RSV, HPV, RABV, VZV, HSV
•Quality control: ISO9001/ ISO13485/ GMP/CMA/CNAS
•6 days to develop SARS-CoV-2 Spike RBD protein
•2 to 1,500L bioreactors, μg-kg level
•Support global IVD companies
•Purity verified by SDS-PAGE/HPLC
•Bioactivity verified by ELISA/SPR/BLI
•High stability, high lot-to-lot consistency
•Unmatched sensitivity: Detect one cell in a million.
•Minimal background: Achieve high signal-to-noise ratio results.
•Ready-to-use pre-coated plates: Ensure consistent performance.
•Eight QC release criteria, including specificity and lot-to-lot consistency
•Compliance with ISO 9001 quality system
Solutions for MSCs Therapy
One-stop support for MSCs drug development through all stages to market
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•High specificity, high sensitivity, and high stability
•Multi-fluorescent labels
•Complete range of markers
•Cell-validated flow cytometry antibodies
•High quality ELISA kits
•10+ MSCs efficacy evaluation methods
•Double C certification (CNAS/CMA)
•Full cell bank testing in as fast as 3 months
•4200m2 dual testing centers in Beijing and Suzhou
•Isolation of adipose, bone marrow and human umbilical MSCs
•MSCs recovery, subculture and cryopreservation
•Osteogenic, adipogenic, and chondrogenic differentiation of MSCs
•High purity, high bioactivity, and low endotoxin
•High lot-to-lot consistency
•Vast selection: Covers both research grade and GMP grade cytokines
•Hot targets: IL-7, IL-6, IL-18, EGF, IL-21, TNF-α, IL-1β, etc.
•Elite quality: Validated by SDS-PAGE, SEC-HPLC, ELISA, SPR, BLI, etc.
ADC Development Solutions
Accelerating ADC Development from Discovery to Clinic
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•Covering 90+ hot ADC targets
•High purity, bioactivity, and stability
•Expression in HEK293 cells
•Biosimilar antibody binding
•High purity: > 95% (SDS-PAGE & SEC-HPLC)
•High affinity: validated by ADCs binding assay
•High specificity: specifically recognizes toxins
Research Spotlights
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