NEJM
The New England Journal of Medicine is the world's leading medical journal.
Oral Vancomycin as Secondary Prophylaxis for Prevention of Recurrent Clostridioides difficile Infection
Oral Vancomycin as Secondary Prophylaxis for Prevention of Recurrent Clostridioides difficile Infection
Looking After Our Own
Looking After Our Own
A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias
A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias
A 67-year-old man with interstitial lung disease presented with fever and myalgias. Laboratory testing revealed pancytopenia and elevated aminotransferase levels. A diagnostic test was performed.
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer
Limited level 1 evidence is available on the omission of radiotherapy after breast-conserving surgery in older women with hormone receptor–positive early breast cancer receiving adjuvant endocrine ...
Tuberculous Optochiasmatic Arachnoiditis
Tuberculous Optochiasmatic Arachnoiditis
Transient Global Amnesia
Transient Global Amnesia
The Journey to RSV Vaccines
The Journey to RSV Vaccines
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer
Limited level 1 evidence is available on the omission of radiotherapy after breast-conserving surgery in older women with hormone receptor–positive early breast cancer receiving adjuvant endocrine ...
Uncoupling Metastasis from Tumorigenesis
Uncoupling Metastasis from Tumorigenesis
Reflections of a Black Program Director
Reflections of a Black Program Director
Although a Black residency program director strives to ensure that residents from groups that are underrepresented in medicine never have to experience the discrimination she faced during training,...
Choosing the Right Path toward Polio Eradication
Choosing the Right Path toward Polio Eradication
Continued circulation of wild and attenuated polioviruses suggests that our eradication campaign needs reevaluation. Long-term immunization policies must both protect vaccinees and minimize silent ...
Post-Roe Realities | Intention to Treat
Post-Roe Realities | Intention to Treat
In this episode of “Intention to Treat,” host Rachel Gotbaum takes us to Tennessee and Ohio, where new abortion bans are already harming patients and threatening their physicians. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300935.
Post-Roe Realities | Intention to Treat
Post-Roe Realities | Intention to Treat
In this episode of “Intention to Treat,” host Rachel Gotbaum takes us to Tennessee and Ohio, where new abortion bans are already harming patients and threatening their physicians. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300935.
Aortic Stenosis of No Physiologic Significance
Aortic Stenosis of No Physiologic Significance
THE clinical diagnosis of aortic stenosis remains a difficult problem in many cases, despite recent advances in knowledge of this condition. The classic signs are familiar: a loud, rough aortic sys...
Intention to Treat: Post-Roe Realities
Intention to Treat: Post-Roe Realities
In this episode of “Intention to Treat,” host Rachel Gotbaum takes us to Tennessee and Ohio, where new abortion bans are already harming patients and threatening their physicians. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300935.
New NEJM Image Challenge
New NEJM Image Challenge
Calloused, Hyperpigmented Fingertips
Calloused, Hyperpigmented Fingertips
Facing the New Covid-19 Reality
Facing the New Covid-19 Reality
SARS-CoV-2 will continue to play a major role in our lives for the foreseeable future. The current situation requires navigating complex social, economic, political, and clinical terrain.
Reconstructive Justice — Public Health Policy to End Mass Incarceration
Reconstructive Justice — Public Health Policy to End Mass Incarceration
The abysmal state of U.S. public health and safety cannot be separated from the destructive effects of mass incarceration. Undoing these harms requires abolishing oppressive systems and constructin...
Odontogenic Cutaneous Fistula
Odontogenic Cutaneous Fistula
A 42-year-old woman presented with subacute swelling and pain on the right side of her chin. On examination, there was an area of skin dimpling with overlying scab on the chin and a discolored righ...
A 56-Year-Old Man with Abnormal Results on Liver Testing
A 56-Year-Old Man with Abnormal Results on Liver Testing
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer
Rheumatoid Arthritis
Rheumatoid Arthritis
Please Look at My Baby
Please Look at My Baby
NEJM Notable Articles 2022
NEJM Notable Articles 2022
Covid Vaccines — Playing the Long Game | Intention to Treat
Covid Vaccines — Playing the Long Game | Intention to Treat
Cerebral Cystic Echinococcosis
Cerebral Cystic Echinococcosis
Venkamma’s Dowry
Venkamma’s Dowry
Optimum End-Expiratory Airway Pressure in Patients with Acute Pulmonary Failure
Optimum End-Expiratory Airway Pressure in Patients with Acute Pulmonary Failure
New NEJM Image Challenge
New NEJM Image Challenge
Behind-the-Scenes Investment for Equity in Global Health Research
Behind-the-Scenes Investment for Equity in Global Health Research
Cerebral Alveolar Echinococcosis
Cerebral Alveolar Echinococcosis
Malaria — Epidemiology, Treatment, and Prevention
Malaria — Epidemiology, Treatment, and Prevention
A Breathtaking Discovery
A Breathtaking Discovery
Facing the New Covid-19 Reality
Facing the New Covid-19 Reality
Humoral Innate Immunity and Acute-Phase Proteins
Humoral Innate Immunity and Acute-Phase Proteins
Aldosterone and Treatment-Resistant Hypertension
Aldosterone and Treatment-Resistant Hypertension
Aligning Quality Measures across CMS
Aligning Quality Measures across CMS
Intention to Treat: Covid Vaccines - Playing the Long Game
Intention to Treat: Covid Vaccines - Playing the Long Game
New Image Challenge
New Image Challenge
Cardio-Omentopexy in the Treatment of Angina Pectoris — Report of Two Cases
Cardio-Omentopexy in the Treatment of Angina Pectoris — Report of Two Cases
Effectiveness of Bivalent Covid-19 Boosters
Effectiveness of Bivalent Covid-19 Boosters
Regulating Reproductive Medicine in a World without Roe
Regulating Reproductive Medicine in a World without Roe
Splenic Tuberculosis
Splenic Tuberculosis
Efanescoctocog Alfa in Severe Hemophilia A
Efanescoctocog Alfa in Severe Hemophilia A
The Promise
The Promise
Sources of Innovation in Gene Therapies
Sources of Innovation in Gene Therapies
Atopic Eruption of Pregnancy
Atopic Eruption of Pregnancy
A Girl with Abdominal Pain and Bloody Diarrhea
A Girl with Abdominal Pain and Bloody Diarrhea
A Man with Dizziness and Altered Mental Status
A Man with Dizziness and Altered Mental Status
Orbital Rhabdomyosarcoma
Orbital Rhabdomyosarcoma
Periprosthetic Joint Infection
Periprosthetic Joint Infection
Intention to Treat | a podcast by NEJM Group
Intention to Treat | a podcast by NEJM Group
Aortic Aneurysm, Fever and Hemorrhagic Diathesis in a Forty-Two-Year-Old Woman
Aortic Aneurysm, Fever and Hemorrhagic Diathesis in a Forty-Two-Year-Old Woman
Psychosocial Functioning in Transgender Youth
Psychosocial Functioning in Transgender Youth
New NEJM Image Challenge
New NEJM Image Challenge
Medicare Overpayment for Outpatient Medication
Medicare Overpayment for Outpatient Medication
Hope - Beyond Firearm Trauma
Hope - Beyond Firearm Trauma
Colocolonic Intussusception
Colocolonic Intussusception
Intention to Treat | a podcast by NEJM Group
Intention to Treat | a podcast by NEJM Group
Better Off At Home
Better Off At Home
Social Isolation and Loneliness as Medical Issues
Social Isolation and Loneliness as Medical Issues
Discovery of Ectopic Pregnancy after Attempted Self-Managed Abortion
Discovery of Ectopic Pregnancy after Attempted Self-Managed Abortion
Substantial Neutralization Escape by SARS-CoV-2 Omicron Variants BQ.1.1 and XBB.1
Substantial Neutralization Escape by SARS-CoV-2 Omicron Variants BQ.1.1 and XBB.1
Protection against Reinfection with the Omicron BA.2.75 Subvariant
Protection against Reinfection with the Omicron BA.2.75 Subvariant
A Rural Idyll
A Rural Idyll
A Man with Hypokalemia and Paranoia
A Man with Hypokalemia and Paranoia
New NEJM Image Challenge
New NEJM Image Challenge
Corporate Investors in Primary Care
Corporate Investors in Primary Care
A Man with Hypokalemia and Paranoia
A Man with Hypokalemia and Paranoia
Calcium Polystyrene Sulfonate–Related Colonic Necrosis
Calcium Polystyrene Sulfonate–Related Colonic Necrosis
The Anchor Strategy
The Anchor Strategy
Safety of Inpatient Health Care
Safety of Inpatient Health Care
Response to BA.5 Bivalent Booster
Response to BA.5 Bivalent Booster
Bivalent Covid-19 Vaccines
Bivalent Covid-19 Vaccines
When Weight Impacts Health
When Weight Impacts Health
Commotio Cordis
Commotio Cordis
New Approaches to Chronic Hepatitis B
New Approaches to Chronic Hepatitis B
Locomotor Brachii Sign in Aortic Regurgitation
Locomotor Brachii Sign in Aortic Regurgitation
A Stormy Heart
A Stormy Heart
Death by Ableism
Death by Ableism
A Stormy Heart
A Stormy Heart
Acromegaly
Acromegaly
Death by Ableism
Death by Ableism
Evidence over Politics
Evidence over Politics
Older Adults with Hip Fracture
Older Adults with Hip Fracture
Subconjunctival Hemorrhage in Leptospirosis
Subconjunctival Hemorrhage in Leptospirosis
A Brewing Storm
A Brewing Storm
A Man with Exertional Chest Discomfort
A Man with Exertional Chest Discomfort
NEJM Image Challenge
NEJM Image Challenge
Alcohol-Associated Hepatitis
Alcohol-Associated Hepatitis
New NEJM Image Challenge
New NEJM Image Challenge
A Sense of Belonging
A Sense of Belonging
Serpentine Supravenous Hyperpigmentation
Serpentine Supravenous Hyperpigmentation
Dupilumab in Patients with Eosinophilic Esophagitis
Dupilumab in Patients with Eosinophilic Esophagitis
Revaluing Primary Care
Revaluing Primary Care
A Woman with Postpartum Abdominal Pain and Fever
A Woman with Postpartum Abdominal Pain and Fever
Oxygen Delivery in the Treatment of Anemia
Oxygen Delivery in the Treatment of Anemia
U.S. Health Insurance Coverage and Financing
U.S. Health Insurance Coverage and Financing
New NEJM Image Challenge
New NEJM Image Challenge
On Click Chemistry
On Click Chemistry
Case Records Video: Planning for Radiation Therapy
Case Records Video: Planning for Radiation Therapy
A Woman with Fatigue and Weight Gain
A Woman with Fatigue and Weight Gain
Bispecific Antibodies — What, Why, How?
Bispecific Antibodies — What, Why, How?
Hereditary Geniospasm
Hereditary Geniospasm
Gene Therapy for Dystrophic Epidermolysis Bullosa
Gene Therapy for Dystrophic Epidermolysis Bullosa
Topical Gene Therapy for Epidermolysis Bullosa
Topical Gene Therapy for Epidermolysis Bullosa
A Woman with Fatigue and Weight Gain
A Woman with Fatigue and Weight Gain
Skin Necrosis after Transarterial Chemoembolization
Skin Necrosis after Transarterial Chemoembolization
Mpox Transmission at a Tattoo Parlor
Mpox Transmission at a Tattoo Parlor
Weight Instructional
Weight Instructional
New NEJM Image Challenge
New NEJM Image Challenge
Filarial Dance Sign in Lymphatic Filariasis
Filarial Dance Sign in Lymphatic Filariasis
A Man with Fatigue, Weight Loss, and Pulmonary Nodules
A Man with Fatigue, Weight Loss, and Pulmonary Nodules
Hemochromatosis
Hemochromatosis
New NEJM Image Challenge
New NEJM Image Challenge
Bismuth Subsalicylate Poisoning
Bismuth Subsalicylate Poisoning
The Fresh Assault on Insurance Coverage Mandates
The Fresh Assault on Insurance Coverage Mandates
Cholera in Haiti, Again
Cholera in Haiti, Again
Reemergence of Cholera in Haiti
Reemergence of Cholera in Haiti
Trichomycosis Axillaris
Trichomycosis Axillaris
Resurgence of Cholera in Haiti
Resurgence of Cholera in Haiti
Watch "Mask Wars"
Watch "Mask Wars"
Injustice Disorder
Injustice Disorder
Buprenorphine versus Methadone in Pregnancy
Buprenorphine versus Methadone in Pregnancy
Injustice Disorder
Injustice Disorder
Hiding in Plain Sight
Hiding in Plain Sight
Clinical Implications of Basic Research
Clinical Implications of Basic Research
Iron Chelation for Parkinson’s Disease
Iron Chelation for Parkinson’s Disease
Infantile and Childhood Hydrocephalus
Infantile and Childhood Hydrocephalus
White House Conference on Hunger, Nutrition, and Health
White House Conference on Hunger, Nutrition, and Health
It Ain’t Over Till It’s Over...but It’s Never Over
It Ain’t Over Till It’s Over...but It’s Never Over
Aural Myiasis
Aural Myiasis
Pyogenic Granuloma
Pyogenic Granuloma
Focused Cardiac Ultrasonography
Focused Cardiac Ultrasonography
Climate Change and Vectorborne Diseases
Climate Change and Vectorborne Diseases
New NEJM Image Challenge
New NEJM Image Challenge
A Good Catch
A Good Catch
Iron Deposition from an Intraocular Foreign Body
Iron Deposition from an Intraocular Foreign Body
A Man with Progressive Dyspnea, Neck Swelling, and a Lung Mass
A Man with Progressive Dyspnea, Neck Swelling, and a Lung Mass
Mercury Poisoning
Mercury Poisoning
Gout
Gout
New NEJM Image Challenge
New NEJM Image Challenge
Pyoderma Gangrenosum
Pyoderma Gangrenosum
A Woman with Covid-19 and Delusions
A Woman with Covid-19 and Delusions
A Woman with Covid-19 and Delusions
A Woman with Covid-19 and Delusions
Seat-Belt Sign and Seat-Belt Aorta
Seat-Belt Sign and Seat-Belt Aorta
“Brain Fog” after SARS-CoV-2 Infection
“Brain Fog” after SARS-CoV-2 Infection
Contrast-Enhanced Imaging and Acute Kidney Injury
Contrast-Enhanced Imaging and Acute Kidney Injury
Climate, Pollution, and Children’s Health
Climate, Pollution, and Children’s Health
The Worst Thing
The Worst Thing
Scaphoid Shift Test in Scapholunate Ligament Injury
Scaphoid Shift Test in Scapholunate Ligament Injury
The Zollinger–Ellison Syndrome
The Zollinger–Ellison Syndrome
A Shear Decline
A Shear Decline
New NEJM Image Challenge
New NEJM Image Challenge
Afib Documentary
Afib Documentary
New NEJM Image Challenge
New NEJM Image Challenge
Randomized Trials of Ruxolitinib Cream for Vitiligo
Randomized Trials of Ruxolitinib Cream for Vitiligo
Tinea Nigra
Tinea Nigra
A Man with Postoperative Cardiogenic Shock and Diffuse Rash
A Man with Postoperative Cardiogenic Shock and Diffuse Rash
Myocarditis
Myocarditis
New NEJM Image Challenge
New NEJM Image Challenge
Migraine Institutional
Migraine Institutional
Giant-Cell Arteritis
Giant-Cell Arteritis
Chronic Arsenic Poisoning
Chronic Arsenic Poisoning
A Man with Heartburn, Nausea, and Inability to Eat
A Man with Heartburn, Nausea, and Inability to Eat
Many Calories but Low Body Weight
Many Calories but Low Body Weight
New NEJM Image Challenge
New NEJM Image Challenge
Atrial Fibrillation - Instructional Video
Atrial Fibrillation - Instructional Video
Gun Violence in the United States
Gun Violence in the United States
Erythema Ab Igne
Erythema Ab Igne
Toxic Megacolon Due to Fulminant C. difficile Infection
Toxic Megacolon Due to Fulminant C. difficile Infection
Thinking Outside the Heart
Thinking Outside the Heart
New NEJM Image Challenge
New NEJM Image Challenge
YouTube: Sickle Cell Disease and Gene Therapy
YouTube: Sickle Cell Disease and Gene Therapy
A Newborn Girl with Hypoglycemia
A Newborn Girl with Hypoglycemia
Autosomal Dominant Osteopetrosis
Autosomal Dominant Osteopetrosis
Lepromatous Leprosy
Lepromatous Leprosy
Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease
A Hidden Crisis
A Hidden Crisis
A Man with Chronic Diarrhea and Autoimmune Enteropathy
A Man with Chronic Diarrhea and Autoimmune Enteropathy
Wellens’ Syndrome
Wellens’ Syndrome
New NEJM Image Challenge
New NEJM Image Challenge
Jackstone Calculus in the Bladder
Jackstone Calculus in the Bladder
Burkitt’s Lymphoma
Burkitt’s Lymphoma
New NEJM Image Challenge
New NEJM Image Challenge
A Man with Headache and Progressive Neurologic Dysfunction
A Man with Headache and Progressive Neurologic Dysfunction
Giant Coronary-Artery Aneurysm
Giant Coronary-Artery Aneurysm
Cholesterol Pericarditis
Cholesterol Pericarditis
Inhalational Induction
Inhalational Induction
Metagenomic Sequencing and Infectious Disease
Metagenomic Sequencing and Infectious Disease
A Man with Confusion, Headache, and Fever
A Man with Confusion, Headache, and Fever
Arrhythmogenic Right Ventricular Cardiomyopathy
Arrhythmogenic Right Ventricular Cardiomyopathy
New NEJM Image Challenge
New NEJM Image Challenge
Gallstone Ileus
Gallstone Ileus
New NEJM Image Challenge
New NEJM Image Challenge
Severe Subcutaneous Emphysema
Severe Subcutaneous Emphysema
Combined Degeneration from Nitrous Oxide Use
Combined Degeneration from Nitrous Oxide Use
Telescoping the Diagnostic Process
Telescoping the Diagnostic Process
When Silence Disrupts
When Silence Disrupts
Relative Afferent Pupillary Defect
Relative Afferent Pupillary Defect
A 48-Year-Old Woman with Abdominal Pain
A 48-Year-Old Woman with Abdominal Pain
Lesions of the Ovary and Fallopian Tube
Lesions of the Ovary and Fallopian Tube
NEJM Image Challenge
NEJM Image Challenge
Japanese Encephalitis in Australia
Japanese Encephalitis in Australia
Professionals as Targets in the Culture Wars
Professionals as Targets in the Culture Wars
Rice Bodies in Tenosynovitis Due to Psoriatic Arthritis
Rice Bodies in Tenosynovitis Due to Psoriatic Arthritis
Gallbladder Volvulus
Gallbladder Volvulus
A Woman with Headache and Blurred Vision
A Woman with Headache and Blurred Vision
Neuromyelitis Optica and Its Spectrum
Neuromyelitis Optica and Its Spectrum
Rapid DNA Sequencing in Reproductive Care
Rapid DNA Sequencing in Reproductive Care
New NEJM Image Challenge
New NEJM Image Challenge
Hair Repigmentation Induced by Nilotinib
Hair Repigmentation Induced by Nilotinib
Lupus Pernio in Sarcoidosis
Lupus Pernio in Sarcoidosis
Screening for AF in Asymptomatic Older Adults
Screening for AF in Asymptomatic Older Adults
Bronchiectasis — A Clinical Review
Bronchiectasis — A Clinical Review
Japanese Spotted Fever
Japanese Spotted Fever
New NEJM Image Challenge
New NEJM Image Challenge
Left Atrial Thrombus
Left Atrial Thrombus
Diagnostic Aspirations
Diagnostic Aspirations
Origin and Treatment of Spina Bifida
Origin and Treatment of Spina Bifida
Curtain Sign
Curtain Sign
New NEJM Image Challenge
New NEJM Image Challenge
Tripe Palms
Tripe Palms
A Man with Hypoglycemia
A Man with Hypoglycemia
"Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022"
"Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022"
NEJM Evidence Special Collection
NEJM Evidence Special Collection
Grieving in a Pandemic
Grieving in a Pandemic
Nonketotic Hyperglycemic Hemichorea
Nonketotic Hyperglycemic Hemichorea
Retropharyngeal Abscess
Retropharyngeal Abscess
A Woman with Cavitary Lung Lesions
A Woman with Cavitary Lung Lesions
New NEJM Image Challenge
New NEJM Image Challenge
Drug Reaction with Eosinophilia and Systemic Symptoms
Drug Reaction with Eosinophilia and Systemic Symptoms
A Girl with Fever and Cough
A Girl with Fever and Cough
Pneumolabyrinth and Pneumocochlea
Pneumolabyrinth and Pneumocochlea
Breakthrough Hemolysis after Complement Inhibition
Breakthrough Hemolysis after Complement Inhibition
New NEJM Image Challenge
New NEJM Image Challenge
The Young and the Breathless
The Young and the Breathless
The Portal
The Portal
Fungal Ball in the Urinary Bladder
Fungal Ball in the Urinary Bladder
Pulmonary Embolism
Pulmonary Embolism
New NEJM Image Challenge
New NEJM Image Challenge
Cherry-Red Spot in Tay–Sachs Disease
Cherry-Red Spot in Tay–Sachs Disease
Chalk-Stick Fracture
Chalk-Stick Fracture
A Man with Vision Changes
A Man with Vision Changes
Lawmakers v. The Scientific Realities of Human Reproduction
Lawmakers v. The Scientific Realities of Human Reproduction
Genetic Modification in Pig-to-Human Transplantation
Genetic Modification in Pig-to-Human Transplantation
New NEJM Image Challenge
New NEJM Image Challenge
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation
A Woman with Jaundice and Chronic Diarrhea
A Woman with Jaundice and Chronic Diarrhea
Bumps in the Road
Bumps in the Road
Second Branchial Cleft Cyst
Second Branchial Cleft Cyst
Retinoblastoma
Retinoblastoma
New NEJM Image Challenge
New NEJM Image Challenge
Clinical Examination of the Hip
Clinical Examination of the Hip
A 29-Year-Old Woman with Recurrent Fractures
A 29-Year-Old Woman with Recurrent Fractures
Immune Tolerance after Stem-Cell and Kidney Transplantation
Immune Tolerance after Stem-Cell and Kidney Transplantation
IgG4-Related Ophthalmic Disease
IgG4-Related Ophthalmic Disease
Climate Change, Fossil-Fuel Pollution, and Children’s Health
Climate Change, Fossil-Fuel Pollution, and Children’s Health
A 31-Year-Old Man with Perianal and Penile Ulcers, Rectal Pain, and Rash
A 31-Year-Old Man with Perianal and Penile Ulcers, Rectal Pain, and Rash
Nineteen Days in America
Nineteen Days in America
New NEJM Image Challenge
New NEJM Image Challenge
Legg–Calvé–Perthes Disease
Legg–Calvé–Perthes Disease
Sclerokeratitis in Granulomatosis with Polyangiitis
Sclerokeratitis in Granulomatosis with Polyangiitis
Diagnosis and Treatment of Frostbite
Diagnosis and Treatment of Frostbite
A 17-Year-Old Boy with Chest Pain
A 17-Year-Old Boy with Chest Pain
Turbocharging the T-Cell to Fight Cancer
Turbocharging the T-Cell to Fight Cancer
Eruptive Xanthomas
Eruptive Xanthomas
New NEJM Image Challenge
New NEJM Image Challenge
Eruptive Xanthomas with Branching Projections
Eruptive Xanthomas with Branching Projections
The After-Dinner Dip
The After-Dinner Dip
T Cells That Specifically Target Tumor
T Cells That Specifically Target Tumor
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer
Second Annual NEJM Medical Fiction Contest
Second Annual NEJM Medical Fiction Contest
E Pluribus Unum
E Pluribus Unum
New NEJM Image Challenge
New NEJM Image Challenge
Carcinoid Heart Disease
Carcinoid Heart Disease
Reactive Arthritis
Reactive Arthritis
A 55-Year-Old Man with Fevers, Night Sweats, and a Mediastinal Mass
A 55-Year-Old Man with Fevers, Night Sweats, and a Mediastinal Mass
Gliflozins in the Management of Cardiovascular Disease
Gliflozins in the Management of Cardiovascular Disease
New NEJM Image Challenge
New NEJM Image Challenge
Gaucher’s Disease
Gaucher’s Disease
Catching Up on REMs
Catching Up on REMs
Syphilitic Aortitis
Syphilitic Aortitis
Physicians Spreading Misinformation on Social Media — Do Right and Wrong Answers Still Exist in Medicine?
Physicians Spreading Misinformation on Social Media — Do Right and Wrong Answers Still Exist in Medicine?
Progress toward Pig-to-Human Xenotransplantation
Progress toward Pig-to-Human Xenotransplantation
A 57-Year-Old Man with Persistent Cough and Pulmonary Opacities
A 57-Year-Old Man with Persistent Cough and Pulmonary Opacities
Brain Tumors in Children
Brain Tumors in Children
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation
Unmute
Unmute
Retinal Hemorrhages in Leukemia
Retinal Hemorrhages in Leukemia
Preeclampsia
Preeclampsia
Emphysematous Aortitis
Emphysematous Aortitis
Climate Change in the Supreme Court
Climate Change in the Supreme Court
A Man with Chylous Ascites
A Man with Chylous Ascites
Looking Back
Looking Back
Your Money or Your Life — The High Cost of Cancer Drugs under Medicare Part D
Your Money or Your Life — The High Cost of Cancer Drugs under Medicare Part D
Foreign-Body Aspiration in a Child
Foreign-Body Aspiration in a Child
A New Image for Cell Sorting
A New Image for Cell Sorting
Nasal High-Flow Therapy during Endotracheal Intubation
Nasal High-Flow Therapy during Endotracheal Intubation
Needlestick
Needlestick
Ocular Gonorrhea
Ocular Gonorrhea
Iris Atrophy in Sickle Cell Disease
Iris Atrophy in Sickle Cell Disease
A 56-Year-Old Man with Myalgias, Fever, and Bradycardia
A 56-Year-Old Man with Myalgias, Fever, and Bradycardia
Effectiveness of Covid-19 Vaccines against the Omicron Variant
Effectiveness of Covid-19 Vaccines against the Omicron Variant
New NEJM Image Challenge
New NEJM Image Challenge
Fighting Cardiac Fibrosis with CAR T Cells
Fighting Cardiac Fibrosis with CAR T Cells
Policy Strategies for Addressing Current Threats to the U.S. Nurse Workforce
Policy Strategies for Addressing Current Threats to the U.S. Nurse Workforce
Congenital Diaphragmatic Hernia in an Adult
Congenital Diaphragmatic Hernia in an Adult
A 41-Year-Old Woman with Transient Ischemic Attack and Mitral Valve Masses
A 41-Year-Old Woman with Transient Ischemic Attack and Mitral Valve Masses
Larva Currens in Strongyloides Hyperinfection Syndrome
Larva Currens in Strongyloides Hyperinfection Syndrome
Physicians as Political Pawns — The Texas Directive on Gender-Affirming Care and Other Moves
Physicians as Political Pawns — The Texas Directive on Gender-Affirming Care and Other Moves
Increasing Incidence of Early-Onset Colorectal Cancer
Increasing Incidence of Early-Onset Colorectal Cancer
From Resentment to Reconnection — Reflections on Caring for the Unvaccinated
From Resentment to Reconnection — Reflections on Caring for the Unvaccinated
Mitapivat vs. Placebo for Pyruvate Kinase Deficiency
Mitapivat vs. Placebo for Pyruvate Kinase Deficiency
An 80-Year-Old Woman with Pancytopenia
An 80-Year-Old Woman with Pancytopenia
New NEJM Image Challenge
New NEJM Image Challenge
Cancer-Associated Hypercalcemia
Cancer-Associated Hypercalcemia
The Tobacco Wars’ Lessons for the Vaccination Wars
The Tobacco Wars’ Lessons for the Vaccination Wars
Radiographic Evolution of Presumed Septic Pulmonary Emboli
Radiographic Evolution of Presumed Septic Pulmonary Emboli
Continuation of Bisphosphonate Therapy for Osteoporosis beyond 5 Years
Continuation of Bisphosphonate Therapy for Osteoporosis beyond 5 Years
After COP26 — Putting Health and Equity at the Center of the Climate Movement
After COP26 — Putting Health and Equity at the Center of the Climate Movement
Origins of Calcific Aortic Stenosis
Origins of Calcific Aortic Stenosis
Population Immunity and Covi-19 Serverity with Omicron Variant
Population Immunity and Covi-19 Serverity with Omicron Variant
A Burning Question
A Burning Question
Ten Years of Choosing Wisely to Reduce Low-Value Care
Ten Years of Choosing Wisely to Reduce Low-Value Care
External Ophthalmomyiasis Due to Oestrus ovis
External Ophthalmomyiasis Due to Oestrus ovis
Prone Positioning of Intubated Patients with an Elevated Body-Mass Index
Prone Positioning of Intubated Patients with an Elevated Body-Mass Index
Thrombectomy in Acute Ischemic Stroke
Thrombectomy in Acute Ischemic Stroke
Laboratory Diagnosis of Creutzfeldt–Jakob Disease
Laboratory Diagnosis of Creutzfeldt–Jakob Disease
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy
Health Care Reform under the Biden Administration — Broad Ambitions, Narrow Majorities
Health Care Reform under the Biden Administration — Broad Ambitions, Narrow Majorities
Single-Incision Mini-Slings for Urinary Incontinence in Women
Single-Incision Mini-Slings for Urinary Incontinence in Women
Restrictive State Abortion Bans — A Reproductive Injustice
Restrictive State Abortion Bans — A Reproductive Injustice
Intestinal Tuberculosis
Intestinal Tuberculosis
“The Sombre Aspect of the Entire Landscape” — Epidemiology and the Faroe Islands
“The Sombre Aspect of the Entire Landscape” — Epidemiology and the Faroe Islands
New NEJM Image Challenge
New NEJM Image Challenge
Supporting Health Care Workers to Address Misinformation on Social Media
Supporting Health Care Workers to Address Misinformation on Social Media
Cholesterol Embolization Syndrome after Carotid-Artery Stenting
Cholesterol Embolization Syndrome after Carotid-Artery Stenting
A 78-Year-Old Man with Marked Ventricular Wall Thickening
A 78-Year-Old Man with Marked Ventricular Wall Thickening
Visual Abstract: Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia
Visual Abstract: Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia
New NEJM Image Challenge
New NEJM Image Challenge
NPO
NPO
Melanoma of the Palpebral Conjunctiva and Eyelid
Melanoma of the Palpebral Conjunctiva and Eyelid
A Boost for Muscle with Gene Therapy
A Boost for Muscle with Gene Therapy
Concomitant Urinary Triple Phosphate and Cystine Crystals
Concomitant Urinary Triple Phosphate and Cystine Crystals
A 56-Year-Old Woman with Fever, Myalgias, Diarrhea, and Cough
A 56-Year-Old Woman with Fever, Myalgias, Diarrhea, and Cough
Current Management of Glycemia in Children with Type 1 Diabetes Mellitus
Current Management of Glycemia in Children with Type 1 Diabetes Mellitus
Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A
Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A
A 54-Year-Old Woman with Episodes of Swelling
A 54-Year-Old Woman with Episodes of Swelling
The Patient Resident
The Patient Resident
Where Americans Die — Is There Really “No Place Like Home”?
Where Americans Die — Is There Really “No Place Like Home”?
Malignant Syphilis
Malignant Syphilis
New NEJM Image Challenge
New NEJM Image Challenge
Pneumatosis Intestinalis in Necrotizing Enterocolitis
Pneumatosis Intestinalis in Necrotizing Enterocolitis
Human Infection with an Avian-Origin Influenza A (H10N3) Virus
Human Infection with an Avian-Origin Influenza A (H10N3) Virus
Cryptogenic Organizing Pneumonia
Cryptogenic Organizing Pneumonia
Visual Abstract: Effectiveness of Covid-19 Vaccines over a 9-Month Period
Visual Abstract: Effectiveness of Covid-19 Vaccines over a 9-Month Period
Tumor-Infiltrating T Cells — A Portrait
Tumor-Infiltrating T Cells — A Portrait
When Desperate Patients Go to Court for Unproven Treatments — Who Wins the Battle for Hospital Independence?
When Desperate Patients Go to Court for Unproven Treatments — Who Wins the Battle for Hospital Independence?
"Use of eFAST in Patients with Injury to the Thorax or Abdomen"
"Use of eFAST in Patients with Injury to the Thorax or Abdomen"
The Catfish King
The Catfish King
Pellagra
Pellagra
New NEJM Image Challenge
New NEJM Image Challenge
A 65-Year-Old Woman with Depression, Recurrent Falls, and Inability to Care for Herself
A 65-Year-Old Woman with Depression, Recurrent Falls, and Inability to Care for Herself
Primary Hyperoxaluria
Primary Hyperoxaluria
Extracorporeal Kidney-Replacement Therapy for Acute Kidney Injury
Extracorporeal Kidney-Replacement Therapy for Acute Kidney Injury
Craving Answers
Craving Answers
Holding the Baby
Holding the Baby
Visual Abstract: Balanced Multielectrolyte Solution vs. Saline in Critically Ill Adults
Visual Abstract: Balanced Multielectrolyte Solution vs. Saline in Critically Ill Adults
Oral Health for All
Oral Health for All
U.S. Public Health Law
U.S. Public Health Law
Primary Hypertrophic Osteoarthropathy
Primary Hypertrophic Osteoarthropathy
New NEJM Image Challenge
New NEJM Image Challenge
Isolated Persistent Left Superior Vena Cava
Isolated Persistent Left Superior Vena Cava
Chronic Pancreatitis
Chronic Pancreatitis
Cellular Memories — More Than Skin Deep
Cellular Memories — More Than Skin Deep
Lymphatic Plastic Bronchitis
Lymphatic Plastic Bronchitis
New NEJM Image Challenge
New NEJM Image Challenge
Plastic Bronchitis
Plastic Bronchitis
Reassessing Human Adipose Tissue
Reassessing Human Adipose Tissue
Home Help
Home Help
A Call for Antiracist Action
A Call for Antiracist Action
Visual Abstract: RSV Inhibitor EDP-938 in a Human Virus Challenge
Visual Abstract: RSV Inhibitor EDP-938 in a Human Virus Challenge
Health Care Safety during the Pandemic and Beyond — Building a System That Ensures Resilience
Health Care Safety during the Pandemic and Beyond — Building a System That Ensures Resilience
Pharyngolaryngeal Hematomas in Hemophilia A
Pharyngolaryngeal Hematomas in Hemophilia A
New NEJM Image Challenge
New NEJM Image Challenge
Images in Clinical Medicine: Page Kidneys
Images in Clinical Medicine: Page Kidneys
Fetal-like Hemoglobin in Sickle Cell Anemia
Fetal-like Hemoglobin in Sickle Cell Anemia
A 55-Year-Old Man with Bilateral Hearing Loss and Eye Redness
A 55-Year-Old Man with Bilateral Hearing Loss and Eye Redness
Visual Abstract: Pembrolizumab for Early Triple-Negative Breast Cancer
Visual Abstract: Pembrolizumab for Early Triple-Negative Breast Cancer
Beyond Diversity — Time for New Models of Health
Beyond Diversity — Time for New Models of Health
Racial Biology and Medical Misconceptions
Racial Biology and Medical Misconceptions
Chronic Generalized Pruritus
Chronic Generalized Pruritus
A Pernicious Cycle Affecting Premalignant Stem Cells
A Pernicious Cycle Affecting Premalignant Stem Cells
New NEJM Image Challenge
New NEJM Image Challenge
A New Way to Contain Unaffordable Medication Costs — Exercising the Government’s Existing Rights
A New Way to Contain Unaffordable Medication Costs — Exercising the Government’s Existing Rights
Molluscum Contagiosum
Molluscum Contagiosum
Marginal-Zone Lymphomas
Marginal-Zone Lymphomas
Trade-offs and Policy Options — Using Insights from Economics to Inform Public Health Policy
Trade-offs and Policy Options — Using Insights from Economics to Inform Public Health Policy
Visual Abstract: Betibeglogene Autotemcel Gene Therapy for Non–β0/β0 Genotype β-Thalassemia
Visual Abstract: Betibeglogene Autotemcel Gene Therapy for Non–β0/β0 Genotype β-Thalassemia
Orbital Necrotizing Fasciitis
Orbital Necrotizing Fasciitis
New NEJM Image Challenge
New NEJM Image Challenge
Calm before the Storm
Calm before the Storm
Lisch Nodules
Lisch Nodules
The Care I Needed
The Care I Needed
Sitting in Our Discomfort
Sitting in Our Discomfort
High-Altitude Travel with Medical Problems
High-Altitude Travel with Medical Problems
Strengthening the Medicaid Reentry Act — Supporting the Health of People Who Are Incarcerated
Strengthening the Medicaid Reentry Act — Supporting the Health of People Who Are Incarcerated
Spur-Cell Hemolytic Anemia
Spur-Cell Hemolytic Anemia
New NEJM Image Challenge
New NEJM Image Challenge
Transparency and the Doctor–Patient Relationship
Transparency and the Doctor–Patient Relationship
Eosinophilic Granulomatosis with Polyangiitis
Eosinophilic Granulomatosis with Polyangiitis
A Boy with Fever, Joint Pain, and Abdominal Cramping
A Boy with Fever, Joint Pain, and Abdominal Cramping
Trastuzumab Deruxtecan in HER2-Mutant Non–Small-Cell Lung Cancer
Trastuzumab Deruxtecan in HER2-Mutant Non–Small-Cell Lung Cancer
Disability Inclusion and Research Study Diversity
Disability Inclusion and Research Study Diversity
Research Participation in Marginalized Communities
Research Participation in Marginalized Communities
Lisfranc Injury
Lisfranc Injury
New NEJM Image Challenge
New NEJM Image Challenge
A Man with a Recurrent Left Pleural Effusion
A Man with a Recurrent Left Pleural Effusion
Combating Structural Inequities
Combating Structural Inequities
Pulmonary-Artery Aneurysm with Acute Dissection
Pulmonary-Artery Aneurysm with Acute Dissection
Visual Abstract: Covid-19 Vaccine Effectiveness in New York State
Visual Abstract: Covid-19 Vaccine Effectiveness in New York State
New NEJM Image Challenge
New NEJM Image Challenge
Reengineering GME in a Pandemic — Looking Back, and Forward
Reengineering GME in a Pandemic — Looking Back, and Forward
Clinical Implications of Basic Research
Clinical Implications of Basic Research
Expanded Lung and Colorectal Cancer Screening — Ensuring Equity and Safety under New Guidelines
Expanded Lung and Colorectal Cancer Screening — Ensuring Equity and Safety under New Guidelines
A Man with Motor Neuron Disease and Odd Behaviors during Sleep
A Man with Motor Neuron Disease and Odd Behaviors during Sleep
Abortion Training in Medical Education — Implications of the Supreme Court’s Upcoming Decision
Abortion Training in Medical Education — Implications of the Supreme Court’s Upcoming Decision
Hyperpigmentation in Vitamin B12 Deficiency
Hyperpigmentation in Vitamin B12 Deficiency
Biologic Therapies for Severe Asthma
Biologic Therapies for Severe Asthma
The Doctor’s Oldest Tool
The Doctor’s Oldest Tool
Obstacles to Physicians’ Emotional Health
Obstacles to Physicians’ Emotional Health
Confused about Confusion
Confused about Confusion
Free-Floating Cyst in the Vitreous
Free-Floating Cyst in the Vitreous
New NEJM Image Challenge
New NEJM Image Challenge
Snake Envenomation
Snake Envenomation
Gingival Infiltration in Acute Monocytic Leukemia
Gingival Infiltration in Acute Monocytic Leukemia
Covid-19's Devastating Effect of Tuberculosis Care
Covid-19's Devastating Effect of Tuberculosis Care
Azithromycin for Yaws Eradication
Azithromycin for Yaws Eradication
Calling Out Aversive Racism in Academic Medicine
Calling Out Aversive Racism in Academic Medicine
Trust, Faith, and Covid
Trust, Faith, and Covid
Visual Abstract: Dolutegravir as First- or Second-Line HIV Treatment in Children
Visual Abstract: Dolutegravir as First- or Second-Line HIV Treatment in Children
Carcinoma en Cuirasse
Carcinoma en Cuirasse
New NEJM Image Challenge
New NEJM Image Challenge
First Impressions — Should We Include Race or Ethnicity at the Beginning of Clinical Case Presentations?
First Impressions — Should We Include Race or Ethnicity at the Beginning of Clinical Case Presentations?
Untreated Chronic Gout
Untreated Chronic Gout
A Boy with Transient Weakness, Facial Droop, and Slurred Speech
A Boy with Transient Weakness, Facial Droop, and Slurred Speech
Evaluation and Assessment of Brain Death
Evaluation and Assessment of Brain Death
Adolescents, Parents, and Covid-19 Vaccination — Who Should Decide?
Adolescents, Parents, and Covid-19 Vaccination — Who Should Decide?
In Clinical Care, What Will Amazon Deliver?
In Clinical Care, What Will Amazon Deliver?
A Woman with Respiratory Failure and Altered Mental Status
A Woman with Respiratory Failure and Altered Mental Status
New NEJM Image Challenge
New NEJM Image Challenge
Tobacco-free Nicotine — New Name, Same Scheme?
Tobacco-free Nicotine — New Name, Same Scheme?
Transplantable Tissue — Immune and Genome Engineering
Transplantable Tissue — Immune and Genome Engineering
" “Please Don’t Keep Me”"
" “Please Don’t Keep Me”"
Ms. Omega One
Ms. Omega One
A Woman with Abdominal Pain, Weight Loss, and Memory Impairment
A Woman with Abdominal Pain, Weight Loss, and Memory Impairment
E66.01 and Our Culture of Shame
E66.01 and Our Culture of Shame
Linear Darier’s Disease
Linear Darier’s Disease
New NEJM Image Challenge
New NEJM Image Challenge
A Failure to Disseminate Transformative Science
A Failure to Disseminate Transformative Science
Tongue Necrosis in Giant-Cell Arteritis
Tongue Necrosis in Giant-Cell Arteritis
Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
The Wild West of Checkpoint Inhibitor Development
The Wild West of Checkpoint Inhibitor Development
A Hot and Tactile Nobel Prize
A Hot and Tactile Nobel Prize
Universal Coronavirus Vaccines — An Urgent Need
Universal Coronavirus Vaccines — An Urgent Need
Inequitable Access to Hospital Care
Inequitable Access to Hospital Care
Transverse Nasal Creases
Transverse Nasal Creases
New NEJM Image Challenge
New NEJM Image Challenge
Congenital Langerhans-Cell Histiocytosis
Congenital Langerhans-Cell Histiocytosis
A Man with Fevers, Fatigue, Arthralgias, a Mouth Ulcer, and a Rash
A Man with Fevers, Fatigue, Arthralgias, a Mouth Ulcer, and a Rash
Covid-19 and the Safety Net
Covid-19 and the Safety Net
A Font of Protein Structures
A Font of Protein Structures
REGEN-COV Antibody Combination in Outpatients with Covid-19
REGEN-COV Antibody Combination in Outpatients with Covid-19
A “Fluid” Diagnosis
A “Fluid” Diagnosis
Ectopic Tooth in the Nose
Ectopic Tooth in the Nose
New NEJM Image Challenge
New NEJM Image Challenge
The Web We Weave
The Web We Weave
Spontaneous Intracranial Hypotension
Spontaneous Intracranial Hypotension
Morel–Lavallée Lesion
Morel–Lavallée Lesion
Using Policy Tools to Improve Population Health
Using Policy Tools to Improve Population Health
The Little Things
The Little Things
Osteosarcoma
Osteosarcoma
Medicare Coverage of Aducanumab
Medicare Coverage of Aducanumab
Tinea Capitis Due to Microsporum canis
Tinea Capitis Due to Microsporum canis
New NEJM Image Challenge
New NEJM Image Challenge
Why Is Aducanumab Priced at $56,000 per Patient?
Why Is Aducanumab Priced at $56,000 per Patient?
Pyostomatitis Vegetans
Pyostomatitis Vegetans
A Man with Pain and Erythema of the Left Hand
A Man with Pain and Erythema of the Left Hand
A Divisive Ruling on Devices
A Divisive Ruling on Devices
Revival
Revival
Visual Abstract: HSPC Gene Therapy for Hurler Syndrome
Visual Abstract: HSPC Gene Therapy for Hurler Syndrome
Salt Handling and Blood Pressure
Salt Handling and Blood Pressure
Drug-Pricing Debate Redux
Drug-Pricing Debate Redux
On Hunger and Mood
On Hunger and Mood
Gingival Melanoma
Gingival Melanoma
New NEJM Image Challenge
New NEJM Image Challenge
Regulating Drug Prices while Increasing Innovation
Regulating Drug Prices while Increasing Innovation
Retinopathy in Malignant Hypertension
Retinopathy in Malignant Hypertension
A Woman with Pain in the Left Upper Quadrant and Hypoxemia
A Woman with Pain in the Left Upper Quadrant and Hypoxemia
Coverage of Transvenous Pulmonary Embolectomy
Coverage of Transvenous Pulmonary Embolectomy
The 100,000 Genomes Pilot on Rare-Disease Diagnosis
The 100,000 Genomes Pilot on Rare-Disease Diagnosis
Pollution and the Heart
Pollution and the Heart
A Man with Altered Mental Status and New Onset of Seizures
A Man with Altered Mental Status and New Onset of Seizures
Ocular Findings in the Sturge–Weber Syndrome
Ocular Findings in the Sturge–Weber Syndrome
New NEJM Image Challenge
New NEJM Image Challenge
When Women and Children Made the Policy Agenda
When Women and Children Made the Policy Agenda
Screening for Cervical Cancer
Screening for Cervical Cancer
Yellow Sac Spider Bite
Yellow Sac Spider Bite
The Future of SARS-CoV-2 Vaccination
The Future of SARS-CoV-2 Vaccination
Relief in Sight
Relief in Sight
Visual Abstract: Efficacy and Safety of Itepekimab for Moderate-to-Severe Asthma
Visual Abstract: Efficacy and Safety of Itepekimab for Moderate-to-Severe Asthma
A Therapeutic Relationship
A Therapeutic Relationship
The 2021 Reauthorization of CAPTA
The 2021 Reauthorization of CAPTA
Disseminated Cryptococcosis
Disseminated Cryptococcosis
New NEJM Image Challenge
New NEJM Image Challenge
A Man with Painful Mouth Ulcers
A Man with Painful Mouth Ulcers
Abdominal Aortic Aneurysms
Abdominal Aortic Aneurysms
Pediatric Achalasia
Pediatric Achalasia
Uncomfortable Truths
Uncomfortable Truths
Aquaporin-1 Expression and Ultrafiltration of the Peritoneal Membrane
Aquaporin-1 Expression and Ultrafiltration of the Peritoneal Membrane
“All Labor Has Dignity”
“All Labor Has Dignity”
Closing the Gender Pay Gap in Medicine
Closing the Gender Pay Gap in Medicine
New NEJM Image Challenge
New NEJM Image Challenge
Blood Donation by Gay and Bisexual Men
Blood Donation by Gay and Bisexual Men
AQP1 Promoter Variant and Peritoneal Dialysis
AQP1 Promoter Variant and Peritoneal Dialysis
A Girl with Swelling of the Jaw and Hypercalcemia
A Girl with Swelling of the Jaw and Hypercalcemia
A Good Death?
A Good Death?
Decarbonizing the U.S. Health Sector
Decarbonizing the U.S. Health Sector
Autoimmune Hemolytic Anemias
Autoimmune Hemolytic Anemias
Visual Abstract: Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19
Visual Abstract: Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19
Hard to Swallow
Hard to Swallow
Integrating Research into Community Practice
Integrating Research into Community Practice
New NEJM Image Challenge
New NEJM Image Challenge
Casual Inference and Observational Studies
Casual Inference and Observational Studies
Intracardiac Cement Embolism
Intracardiac Cement Embolism
Methods of Public Health Research
Methods of Public Health Research
Are Covid-19 Vaccine Boosters Necessary?
Are Covid-19 Vaccine Boosters Necessary?
Newer Biologic and Small-Molecule Therapies for IBD
Newer Biologic and Small-Molecule Therapies for IBD
Visual Abstract: Ozanimod Therapy for Ulcerative Colitis
Visual Abstract: Ozanimod Therapy for Ulcerative Colitis
Hard to Swallow
Hard to Swallow
Cool Water
Cool Water
Wnt Proteins and Structural Birth Defects
Wnt Proteins and Structural Birth Defects
Kayser–Fleischer Rings in Wilson’s Disease
Kayser–Fleischer Rings in Wilson’s Disease
A Man with Recurrent Head and Neck Pain
A Man with Recurrent Head and Neck Pain
Examining the Indian Health System
Examining the Indian Health System
Leukemia Cutis
Leukemia Cutis
Toward a New Era for the Indian Health System
Toward a New Era for the Indian Health System
Covid-19 and the Media
Covid-19 and the Media
Optogenetics Recognized through the Lasker Award
Optogenetics Recognized through the Lasker Award
mRNA Vaccine Research and the Lasker–DeBakey Award
mRNA Vaccine Research and the Lasker–DeBakey Award
Visual Abstract: Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19
Visual Abstract: Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19
A 12-Month-Old Boy with Fever and Developmental Regression
A 12-Month-Old Boy with Fever and Developmental Regression
Ocular Thelaziasis
Ocular Thelaziasis
New NEJM Image Challenge
New NEJM Image Challenge
Legal Challenges to Covid-19 Measures
Legal Challenges to Covid-19 Measures
Symblepharon in Linear IgA Bullous Dermatosis
Symblepharon in Linear IgA Bullous Dermatosis
The No Surprises Act and Informed Financial Consent
The No Surprises Act and Informed Financial Consent
Mask Wars
Mask Wars
Vaccine Efficacy and Boosters in Covid-19
Vaccine Efficacy and Boosters in Covid-19
Vigilante Injustice — Deputizing and Weaponizing the Public to Stop Abortions
Vigilante Injustice — Deputizing and Weaponizing the Public to Stop Abortions
Visual Abstract: Typhoid Vaccine in Malawian Children
Visual Abstract: Typhoid Vaccine in Malawian Children
Conjunctival Kaposi’s Sarcoma
Conjunctival Kaposi’s Sarcoma
New NEJM Image Challenge
New NEJM Image Challenge
Placenta Increta
Placenta Increta
Podcast: New Evidence on SARS-CoV-2 Vaccine Boosters
Podcast: New Evidence on SARS-CoV-2 Vaccine Boosters
Circuitous Route to Understanding CCMs
Circuitous Route to Understanding CCMs
Gingival Ulceration
Gingival Ulceration
Challenges of Sarcoidosis and Its Management
Challenges of Sarcoidosis and Its Management
Peak Moments – When Kindergarten Is High-Risk
Peak Moments – When Kindergarten Is High-Risk
New NEJM Image Challenge
New NEJM Image Challenge
Amoxicillin Rash in Infectious Mononucleosis
Amoxicillin Rash in Infectious Mononucleosis
Covid-19 podcast: Protecting against Severe Disease and Transmission
Covid-19 podcast: Protecting against Severe Disease and Transmission
Paying for Digital Health Care — Problems with the Fee-for-Service System
Paying for Digital Health Care — Problems with the Fee-for-Service System
Clinical Problem Solving: Inadequate Support
Clinical Problem Solving: Inadequate Support
Visual Abstract: Effectiveness of an Inactivated SARS-CoV-2 Vaccine
Visual Abstract: Effectiveness of an Inactivated SARS-CoV-2 Vaccine
Chronic Meningitis
Chronic Meningitis
Abdominopelvic Actinomycosis
Abdominopelvic Actinomycosis
New NEJM Image Challenge
New NEJM Image Challenge
Public Health Law after Covid-19
Public Health Law after Covid-19
Loiasis
Loiasis
Forgetting Past Lessons about Structural Racism
Forgetting Past Lessons about Structural Racism
Triple Therapy for Cystic Fibrosis
Triple Therapy for Cystic Fibrosis
Modeling Human Cardiac Chambers with Organoids
Modeling Human Cardiac Chambers with Organoids
A Man with Relapsed Acute Myeloid Leukemia
A Man with Relapsed Acute Myeloid Leukemia
Circinate Syphilitic Lesions
Circinate Syphilitic Lesions
New NEJM Image Challenge
New NEJM Image Challenge
Podcast: Breaking Down the Aducanumab Case
Podcast: Breaking Down the Aducanumab Case
Hypervirulent Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae
Covid-19 podcast: Assessing Vaccine Safety
Covid-19 podcast: Assessing Vaccine Safety
Atogepant for the Preventive Treatment of Migraine
Atogepant for the Preventive Treatment of Migraine
Lorlatinib Response in ALK-Fusion–Positive Glioma
Lorlatinib Response in ALK-Fusion–Positive Glioma
Malignant Peripheral Nerve-Sheath Tumor
Malignant Peripheral Nerve-Sheath Tumor
New NEJM Image Challenge
New NEJM Image Challenge
A Man with Fatigue and Leg Swelling
A Man with Fatigue and Leg Swelling
Intussusception in the Peutz–Jeghers Syndrome
Intussusception in the Peutz–Jeghers Syndrome
Medicare Physician Payment Reform
Medicare Physician Payment Reform
Aspects of Covid-19 Immunity
Aspects of Covid-19 Immunity
Environmental Racism and Climate Change
Environmental Racism and Climate Change
Abelacimab for Prevention of Venous Thromboembolism
Abelacimab for Prevention of Venous Thromboembolism
New NEJM Image Challenge
New NEJM Image Challenge
Copper Deficiency
Copper Deficiency
Signature Cytokines and Immune-Mediated Inflammatory Diseases
Signature Cytokines and Immune-Mediated Inflammatory Diseases
Myiasis from Botfly Larvae
Myiasis from Botfly Larvae
A Woman with Fever, Sore Throat, and Confusion
A Woman with Fever, Sore Throat, and Confusion
When Low Tech Wins
When Low Tech Wins
A New Dimension in the RNA World
A New Dimension in the RNA World
Age-Related Macular Degeneration
Age-Related Macular Degeneration
Visual Abstract: Milrinone vs. Dobutamine in Cardiogenic Shock
Visual Abstract: Milrinone vs. Dobutamine in Cardiogenic Shock
New NEJM Image Challenge
New NEJM Image Challenge
Turning Purple with Pain
Turning Purple with Pain
Keeping Our Promise
Keeping Our Promise
Neutrophilic Eccrine Hidradenitis
Neutrophilic Eccrine Hidradenitis
Fundamentals of Public Health: The Complementarity of Public Health and Medicine
Fundamentals of Public Health: The Complementarity of Public Health and Medicine
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