Tag: imaging | Modulight

Modulight Spotlights: LASER-SHARP RESEARCH – December 2025

Laser-sharp Research / imaging, in vitro, in vivo, laser-sharp research, ML6600, multi-wavelength, oxygen, Photodynamic therapy, treatment guidance, treatment monitoring, tumor, ultrasound / December 30, 2025

Deeksha Sankepalle and the group at Tufts University, USA developed an advanced multi-wavelength photoacoustic imaging system. It integrates a pulsed, tunable laser with an ultrasound acquisition platform to provide functional 3D imaging. The system enables real-time, non-invasive, high-resolution imaging of tumor vasculature by tracking oxygen saturation in the tumor.

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Modulight Spotlights: LASER-SHARP RESEARCH – July 2025

Laser-sharp Research / Cancer therapy, imaging, in vitro, in vivo, laser-sharp research, ML6600, oxygen, photoacoutics, theranostics, treatment monitoring, ultrasound / July 22, 2025

The spotlight of the month goes to Andrew Langley et al. at Tufts University, USA, for their impressive work in leveraging photoacoustic imaging for real-time monitoring of phototherapy. Photoacoustic imaging is 3D, non-ionizing and non-invasive imaging method, based on optical absorption that creates pressure waves detected by ultrasound transducer.

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Modulight Spotlights: LASER-SHARP RESEARCH – April 2025

Laser-sharp Research / drug delivery, imaging, in vitro, laser-sharp research, light activation, ML6600, nanoparticles, Photodynamic therapy, Photoimmunotherapy, verteporfin / April 30, 2025

Gokalp et al. from University of Massachusetts and Tufts University constructed an innovative liquid metal nanoparticle platform, which has tumor cell targeting and enhanced encapsulation of verteporfin. Charactierization in vitro with the help of ML6600 laser showed effective in vitro phototoxicity.

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Liquid metal nanoparticles for enhanced delivery of benzoporphyrin derivative in photodynamic cancer therapy

Scientific papers / 690 nm, Cancer therapy, imaging, in vitro, ML6600, nanoparticles, PDT, Photodynamic therapy, photosensitizer, phototoxicity, tumor / April 15, 2025

Published in: Photochemistry and Photobiology Authors: Sumeyra Gokalp, Marvin Xavierselvan, Mohammad Forhad Khan, Ronak Shethia, Sima Khani, Ryan H. Riddell, Anna V. Krasnoslobodtseva, Srivalleesha Mallidi, Michelle Foster

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Power scalable speckle-free multi-wavelength light engine for super-resolution microscopy

Scientific papers / 355 nm, 405 nm, 488 nm, 561 nm, 638 nm, BIOS, imaging, laser engine, microscopy, ML6600, narrow linewidth, Photonics West, speckle removal, SPIE, super-resolution microscopy / March 19, 2025

Published in: SPIE BIOS 2025 Authors: Anna Essauolva, Sergei Kuehn, Visa Kaivosoja, Andrei Fedotov, Petteri Uusimaa

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Photodynamic Therapy for Cancer Treatment – Review Article by Nature

Press Releases / collaboration, imaging, PDT, Photodynamic therapy, priming, review article / June 20, 2024

Modulight announces a significant contribution to the field of cancer treatment through the publication of a comprehensive review on Photodynamic Therapy (PDT) in Nature Reviews Bioengineering: “Engineering Photodynamics for Treatment, Priming, and Imaging”.

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Hyperspectral imaging for flow cytometry

Scientific papers / biomedical, flow cytometry, illumination, imaging, ML6600 / January 28, 2024

Published in: SPIE BIOS 2024 Authors: Anna Filipchuk, Robert Perttilä, Ana Colucci, Petteri Uusimaa

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Fluorescence imaging & endoscopy for tumor visualization and diagnostics

Application Note / 5-ALA, bladder cancer, bronchoscopy, cystoscope, cystoscopy, endoscope, endoscopy, fluorescence, gastroscopy, ICG, imaging, indocyanine green, Lung cancer, ML7710, NIR endoscopy, oncology, RGB / July 6, 2022

Several fluorescent agents have been approved for fluorescence based diagnosis & intraoperative imaging: Dye generic name Countries Excitation Detection Indications Indocyanine Green (ICG) Worldwide 800 nm Near-infrared (820 nm) Multiple uses: lymphatic mapping, tissue perfusion, visualization of biliary ducts and blood veins, retinal angiography Fluorescein Worldwide 490 nm Green fluorescence (525 nm) Fluorescein angiography or

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Multimodal imaging microscope for tissue engineering applications

Application Note / 488nm, 561nm, 638nm, imaging, in vitro, microscopy, ML6600, multimodal imaging, OPT, RGB, SPIM, stem cells / September 14, 2021

Motivation for the study Tissue engineering is an evolving field of medicine that aims to grow new viable tissue for repairing or regenerating damaged tissues in the body. These tissue constructs are typically made by placing cells in support matrices that have proper growth-inducing factors. However, visualizing the development and composition of these tissue

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