Tag: PIT | Modulight

Interleukin 15 (IL15)-based near-infrared photoimmunotherapy

Scientific papers / 690 nm, in vitro, in vivo, interleukin15, IR700, light activation, ML7710, National Cancer Institute, NIH, NIR, Photoimmunotherapy, PIT, tumor / August 31, 2025

Published in: Cancer Immunology, Immunotherapy Authors: Motofumi Suzuki, Aki Furusawa, Hiroshi Yamamoto, Makoto Kano, Miyu Kano, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi

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Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor

Scientific papers / 690 nm, in vitro, in vivo, ML7710, NIH, NIR, Osteosarcoma, Photoimmunotherapy, PIT, tumor / October 1, 2024

Published in: Translational Oncology Authors: Motofumi Suzuki, Hisataka Kobayashi, Hirofumi Hanaoka

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Modulight Spotlights: LASER-SHARP RESEARCH – August 2024

Laser-sharp Research / application fiber, diffuser fiber, dyes, endoscopy, esophageal cancer, gastrointestinal, gastroscopy, IRDye700DX, Kill cancer, lateral emitting laser fiber, ML7710, Photoimmunotherapy, PIT, precision, targeted therapies / August 7, 2024

Hirofumi Hanaoka and the team at Kansai Medical University, Japan developed a new laser fiber and method for illumination of narrow cavities, such as esophagus. The new fiber together with ML7710 laser allowed better illumination of the entire tumor compared to existing fibers, resulting in tumor growth suppression.

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Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment

Scientific papers / 690 nm, in vitro, in vivo, ML7710, Photoimmunotherapy, PIT / April 26, 2024

Published in: Cancer Science Authors: Fuyuki F. Inagaki, Makoto Kano, Aki Furusawa, Takuya Kato, Ryuhei Okada, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi

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Photoimmunotechnology as a powerful biological tool for molecular-based elimination of target cells and microbes, including bacteria, fungi and viruses

Scientific papers / antimicrobial, in vitro, in vivo, ML6600, ML7710, MRSA, Photoimmunotherapy, PIAS, PIT / October 4, 2023

Published in: Nature Protocols Authors: Tadayuki Iwase, Kimihiro Ito, Takashi Nishimura, Kei Miyakawa, Akihide Ryo, Hisataka Kobayashi, Makoto Mitsunaga The Jikei University School of Medicine

Photoimmunotechnology as a powerful biological tool for molecular-based elimination of target cells and microbes, including bacteria, fungi and viruses Read More »

Fluorescence-guided photoimmunotherapy using targeted nanotechnology and ML7710 to manage peritoneal carcinomatosis

Scientific papers / carcinomatosis, fluorescence-guided surgery, ML7710, Modulight authors, ovarian cancer, PDT, Photoimmunotherapy, PIT / September 6, 2023

Published in: Science Advances Authors: Barry J. Liang(1,2), Sumiao Pang(1), Robert Perttilä(3), Chen-Hua Ma(1), Payal Srivastava(1), Brandon Gaitan(1), Aaron J. Sorrin (1), Nada Fadul(1), Zoe Ylöniemi(3), Dana M. Roque(4,5), Tayyaba Hasan(6), Petteri Uusimaa(3), Huang-Chiao Huang(1,4*) (1) Fischell Department of Bioengineering, University of Maryland (2) Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute,

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Towards Photodynamic Image-Guided Surgery of Head and Neck Tumors: Photodynamic Priming Improves Delivery and Diagnostic Accuracy of Cetuximab-IRDye800CW

Scientific papers / 690 nm, BPD, cetuximab, fluorescence imaging, H&N cancer, in vivo, IRDye800CW, ML6500, Photoimmunotherapy, PIT, targeted therapies, tumor / June 28, 2022

Published in: Frontiers in Oncology Authors: Chanda Bhandari, John Fakhry, Menitte Eroy, Jane Junghwa Song, Kimberley Samkoe, Tayyaba Hasan, Kenneth Hoyt, Girgis Obaid

Towards Photodynamic Image-Guided Surgery of Head and Neck Tumors: Photodynamic Priming Improves Delivery and Diagnostic Accuracy of Cetuximab-IRDye800CW Read More »

Antitumor Effect and Induced Immune Response Following Exposure of Hexaminolevulinate and Blue Light in Combination with Checkpoint Inhibitor in an Orthotopic Model of Rat Bladder Cancer

Scientific papers / 405 nm, bladder cancer, checkpoint inhibitors, cystoscopy, in vivo, ML6500, ML6600, Photoimmunotherapy, PIT, tumor / February 25, 2022

Published in: Biomedicines Authors: Laureline Lamy, Jacques Thomas, Agnès Leroux, Jean-François Bisson, Kari Myren, Aslak Godal, Gry Stensrud, Lina Bezdetnaya

Antitumor Effect and Induced Immune Response Following Exposure of Hexaminolevulinate and Blue Light in Combination with Checkpoint Inhibitor in an Orthotopic Model of Rat Bladder Cancer Read More »

CD29 targeted near-infrared photoimmunotherapy (NIR-PIT) in the treatment of a pigmented melanoma model

Scientific papers / 690 nm, AbPC, immune checkpoints, in vitro, in vivo, Melanoma, ML7710, Photoimmunotherapy, PIT / January 4, 2022

Published in: OncoImmunology Authors: Aki Furusawa, Ryuhei Okada, Fuyuki Inagaki, Hiroaki Wakiyama, Takuya Kato, Hideyuki Furumoto, Hiroshi Fukushima, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi

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