i2b2: Informatics for Integrating Biology & the Bedside

i2b2: Informatics for Integrating Biology & the Bedside - A National Center for Biomedical Computing

Software

i2b2 Software

Current i2b2 Versions

1.8.2

Use the links below to access the software repository where you will find the source code, executable files, XSD files, PDF files and more.

Quick Launch

Download Binary Distribution

The i2b2 is a collection of both client and server and can be used to install or upgrade the i2b2 Server and webclient. More detailed instructions are located here.

Version: 1.8.2
Release Date: September 30, 2025
License: Mozilla 2 Open Source License

Select the appropriate file below for download:

Download	File Size	Descrption	Installation Guide
i2b2core-new-182.zip	1.9 GB	New Install i2b2 Server	Quick Install
i2b2core-upgrade-182.zip	1.9 GB	Upgrade i2b2 Server	Quick Upgrade

VMWare Image

Below is the complete VMware i2b2 server installed on Linux.

Only supported on VMware fusion and Player.

Version: 1.8.2
Release Date: September 30, 2025
License: Mozilla 2 Open Source License

After you have downloaded and installed the VMware image, please use the following login for CentOS:

CentOS Account
User:	i2b2 (or root)
Password:	demouser

Select the appropriate file below for download:

Download	File Size	Type
i2b2vmware-182-x86_64.zip	8.9 GB	VMware Core Image Windows
i2b2vmware-182-aarch64.zip	9.2 GB	VMware Core Image Mac Silicon
vmware_Install_Guide.pdf	866 kB	VMware Installation Guide

Download Source Code

The i2b2 Source is a collection of both client and server source code and can be used to build the i2b2 Server from scratch. The source code files for the i2b2 Core Hive Cells and Web Client are listed below. Demo data and the current documentation can also be downloaded.

Version: 1.8.2
Release Date: September 30, 2025
License: Mozilla 2 Open Source License

Select the appropriate file below for download:

Download	File Size	Type
i2b2core-src-182.zip	152 MB	Core Source Code Server
i2b2webclient-182.zip	144 MB	Web Client Source
i2b2createdb-182.zip	1.4 GB	i2b2 Data for Oracle, PostgreSQL and Sql Server

Older Versions: Previous releases can be found on the Archived Source Code web page

Documentation

Hover over the modules below for the latest documentation:

Project
Management

Ontology
Management

Data
Repository
(CRC)

File
Repository
(CRC)

Workflow
Framework

Identity
Management

i2b2
Web Client
Application

i2b2
Workbench
Application

Project Management
Core Server Side i2b2 Cell
This cell is used to provide user authentication and manage group and role information. It also keeps track of what cells are part of the hive.
Installation Guide
Messaging Guide
Design Document
Go to Download

Ontology Management
Core Server Side i2b2 Cell
This cell manages the terminology and knowledge information typically used in the hive. It is contacted for, or distributes knowledge to, cells during most of the hives transactions.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download

Data Repository (CRC)
Core Server Side i2b2 Cell
This cell holds the phenotypic and genotypic data of the hive in a structured format. Data queries and visualizations are available through this cell.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Plugin Analysis Document
Go to Download

Workplace Framework
Core Server Side i2b2 Cell
This cell is used to process information in steps through various parts of the hive. Most processed information will come to reside in the Data Repository Cell or as a display to the user.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download

i2b2 Web Client
The i2b2 Web Client is a collection of client-side components designed as an YUI AJAX-based plug-ins that communicate with i2b2 Cells and allow the investigator to query and display the data of the hive.
Install Guide
Project Request Guide
Go to Download

i2b2 Hive
The Hive is a collection of software modules that create a system to allow the use of patient data for research.
i2b2 Hive Introduction
i2b2 Message Wrapper
i2b2 Patient Data Object

i2b2 Workbench
The i2b2 Workbench is a collection of client-side components designed as Eclipse-based java plug-ins that communicate with i2b2 Cells and allow the investigator to query, analyze, and display the data of the hive, generally in greater depth than the web client.
Installation Guide
Tutorial Document
Developer's Guide
Go to Download
Go to Download Source

File Repository
Core Server Side i2b2 Cell
This cell holds large files of data including radiological images and genetic sequences. The files are generally referenced from the Data Repository Cell.
Installation Guide
Messaging Guide
Architecture Document
Go to Download

Identity Management
Core Server Side i2b2 Cell
This cell is used to manage a patient's protected health information in a manner consistent with the HIPAA privacy rule. Patient data is available only as a HIPAA defined "Limited Data Set" to most of the hive.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download

Patient Counts Plug-in
Optional Server Side CRC Plug-in
This server-side CRC plug-in calculates patient count breakdown for the children of a given concept. It is used in conjunction with an enhanced ontology workbench plug-in.
Functional Specification
Go to Download

Older, unsupported add-ons are on the Archived Optional Components page.

Development Tracking

Please submit any bugs that you may encounter using our bug tracking web page.

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