Optical Photothermal Infrared Spectroscopy & Microscopy
Submicron IR with simultaneous Raman spectroscopy, co-located
Fluorescence and high-speed label free IR imaging
Advancing the frontiers of IR spectroscopy
Photothermal Spectroscopy Corp. is advancing the frontiers of vibrational spectroscopy and chemical imaging with breakthrough Optical Photothermal Infrared (O-PTIR) technology. O-PTIR overcomes key limitations of traditional FTIR including poor spatial resolution, time-consuming sample preparation, and spectral artifacts,
O-PTIR uniquely delivers multimodal capabilities for spectroscopy, imaging, and microscopy, combining sub-micron IR with simultaneous co-located Raman, and Fluorescence microscopy. Our mIRage products integrate these in easy to use, high throughput benchtop instruments.
Enable new research, solve key industrial challenges
Using the mIRage product family, scientists can exploit O-PTIR for high-impact research across life science, microplastics, materials science, bio-pharma and beyond.
For industry, mIRage solves critical problems and accelerates data acquisition, including characterising organic contamination, identifying material composition, and pinpointing failure analysis.
Need more information?
Discover how O-PTIR technology can elevate your research or help solve your toughest challenges. Our team are happy to assist and answer your questions.
Explore our products
stRAMos
Photothermal Stimulated Raman Microscope
Sub-300nm Photothermal Stimulated Raman Microscope. Powered by PhotoThermalSRS™
mIRage-HSi
Laser Scanning O-PTIR Microscope
Sub-500nm Laser Scanning O-PTIR Microscope for High-Speed Imaging. With co-located Fluorescence and Raman spectroscopy.
mIRage-LS
Highest resolution IR for life science research
The mIRage-LS addresses both life science applications and the broad application set of multiuser facilities where the most advanced vibrational spectroscopy needs are required.
mIRage
High speed, label free, chemical imaging
A new submicron IR, high-speed widefield chemical imaging mode for measurement of a wide range of labelled and auto fluorescent samples covering cellular, bacterial and tissue applications.
Applications
Multi-modal optical photothermal Infrared spectroscopy is being applied successfully to an increasingly broad range of applications in both academic and industrial labs. Learn more about how O-PTIR can help you advance your research or help solve your critical problems.
Webinars
- Life Science
- November 13, 2025
- Life Science
- October 2, 2025
- Microplastics
- July 23, 2025
- Microplastics
- June 18, 2025
- Life Science | Microplastics
- June 26, 2025
- Life Science
- May 22, 2025
- Microplastics
- March 27, 2025
Upcoming event
- March 22, 2026
ACS Spring 2026
“The capability of the mIRage system to provide submicron simultaneous IR+Raman is truly unique and offers significant advantages compared to other technologies. Moreover, Photothermal team have been amazing to work with!”
Tanya Hutter, Ph.D
Assistant Professor
The University of Texas
at Austin
“The mIRage obtains valuable information about the structure of multilayered plastic films and ageing of adhesives not available to conventional FTIR and Raman. O-PTIR is valuable for the development of high-quality plastic recyclables”
Madina Shamsuyeva, Ph.D
Leibnez University
Hannover, Germany.
Institute for Plastics and Recycling Technology
“Our first user experiment in the field of Alzheimer’s went so well that the researchers are submitting a manuscript to a high impact journal. The OPTIR is a disruptive technology.”
Ferenc Borondics, Ph.D
Principal Beamline Scientist
SOLEIL synchrotron
France
Science portal
Stay at the forefront of scientific innovation with our Knowledge Portal—a curated collection of technical articles, publication briefs, whitepapers, and webinar insights. Dive into groundbreaking research covering bioimaging, sub-micron IR analysis of microplastics, and single-molecule imaging with SERS/SIERA. Discover how Optical Photothermal Infrared (O-PTIR) spectroscopy is driving new advancements across multiple fields.
Need more information?
Discover how O-PTIR technology can elevate your research or help solve your toughest challenges. Our team are happy to assist and answer your questions.