MultiPro Human Discovery Panel

Single cell + protein: One seamless workflow

 
 
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Demonstrated Protocol | Datasets & App Note

One seamless workflow for large-scale multiomics

Every cell has a story that can't be told by RNA alone. Active signaling, phosphorylation states, and surface markers live at the protein level, which means transcript-only approaches can miss the mechanisms driving disease and treatment response.

Our Flex workflow pairs seamlessly with the MultiPro Human Discovery Panel to allow researchers to get at those key details with direct measurement of gene expression plus cell surface and intracellular proteins in one experiment. By bridging gene activity with functional protein insights, researchers can reveal deeper insights into cell identity and dynamics, from external interactions to intracellular regulation.  

Explore our Demonstrated Protocol and datasets below to see how same-cell transcript and protein output can elevate your discovery with:

  • More accurate insights: Maximize data yield and categorize cells based on functional characteristics by labeling nuclear, cytoplasmic, and post-translational modifications

  • Comprehensive multiomics: Capture cell surface, intracellular, and nuclear proteins, including transcription factors, cytokines, metabolic regulators, and more with the most diverse protein panel

  • Consistent, reproducible performance: Ensure efficiency and quality for every run with pre-optimized, single-use, lyophilized panels
Demonstrated Protocol

Our protocol for protein labeling in fixed samples offers flexible storage and logistics, featuring a pre-stain storage step that supports flow sorting at multiple stages and enables labeling of nuclear, cytoplasmic, and post-translational modifications beyond RNA sequencing capabilities.


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Cell surface and intracellular protein labeling for GEM-X Flex v1 and Flex Apex

Access the benefits of same-cell multiomic readouts and the improved scale and performance our GEM-X technology offers, including:

  • Enhanced discovery with a diverse 347-antibody panel
  • Reduced cell input recommendations for scRNA-seq
  • Increased cell throughput and microfluidic recovery
Download now >

Datasets and Application Note

See the power of cell surface and intracellular protein labeling with our freely available datasets.


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8-plex of human DTCs and matched PBMCs
  • MultiPro Human Discovery Panel dataset: labeled with extracellular and intracellular targeting antibodies to analyze kidney and lung DTCs with matched PBMCs using Flex technology.
    Explore the data >

  • See the data in action as we investigate donor-specific signaling pathways in kidney cancer.
    Read the Application Note >

Protein labeling is one of our many capabilities and workflows. Expand your research possibilities with access to the broadest range of analytes, samples, and workflows. Talk to a specialist to learn more about what we can achieve together.

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