
Foundational AI for Biology and Chemistry
Frontier models and high-performance compute for designing all of life's molecules.
We’re creating frontier models for biomolecular modeling and design.
A step change in small-molecule screening and hit discovery, experimentally validated at scale.
New primitives for agentic science
Integrate state-of-the-art biomolecular models into your agentic product or pipeline.
import os
from boltz_api import Boltz
client = Boltz(api_key=os.environ["BOLTZ_API_KEY"])
run_dir = client.small_molecule.design.run(
target={
"entities": [
{"type": "protein", "value": "MKTIIALSYIFCLVFA", "chain_ids": ["A"]},
],
"pocket_residues": {"A": [10, 11, 12]},
},
num_molecules=100,
name="my-design",
)
print(run_dir)Blazing-fast inference
Design thousands of proteins and small molecules in minutes, not days.
Secure deployment
Multi-tenant, single-tenant, or fully on-premise. SOC 2 Type 1 verified.
Fine-tuning
Adapt frontier models to your proprietary data, targets, and assays.
Advancing the open frontier of biomolecular AI.
Boltz PBC builds powerful new models and infrastructure for scientific discovery.
Partner with us
We partner with pioneering teams to tackle the most challenging problems in drug discovery. Reach out to explore how we can accelerate your research.
Join our team
We’re building a world-class team to push the boundaries of AI-driven drug discovery. See our open positions and help shape the future of medicine.













