Boltz protein render

Foundational AI for Biology and Chemistry

Frontier models and high-performance compute for designing all of life's molecules.

Strategic biopharma collaborations

PfizerTakedaGSK

Backed by

a16z
Amplify Partners
Zetta Venture Partners

Available across the tools scientists already use

Benchling
Phylo
Rowan
Tamarind Bio
Kiin Bio
Pauling.ai
Mirror
AWS
5M+downloads
100k+scientists
1k+companies
Top 20pharma companies
Our models

We’re creating frontier models for biomolecular modeling and design.

A step change in small-molecule screening and hit discovery, experimentally validated at scale.

Products

New primitives for agentic science

Integrate state-of-the-art biomolecular models into your agentic product or pipeline.

import os
from boltz_api import Boltz

client = Boltz(api_key=os.environ["BOLTZ_API_KEY"])

run_dir = client.small_molecule.design.run(
    target={
        "entities": [
            {"type": "protein", "value": "MKTIIALSYIFCLVFA", "chain_ids": ["A"]},
        ],
        "pocket_residues": {"A": [10, 11, 12]},
    },
    num_molecules=100,
    name="my-design",
)
print(run_dir)
~15s

Blazing-fast inference

Design thousands of proteins and small molecules in minutes, not days.

DeploymentSOC 2 Type 1
Multi-tenantSingle-tenantOn-premise

Secure deployment

Multi-tenant, single-tenant, or fully on-premise. SOC 2 Type 1 verified.

Fine-tuning

Adapt frontier models to your proprietary data, targets, and assays.

About us

Advancing the open frontier of biomolecular AI.

Boltz PBC builds powerful new models and infrastructure for scientific discovery.

Partner with us

We partner with pioneering teams to tackle the most challenging problems in drug discovery. Reach out to explore how we can accelerate your research.

Join our team

We’re building a world-class team to push the boundaries of AI-driven drug discovery. See our open positions and help shape the future of medicine.