RNAgri is a startup making huge progress in RNA production and RNAi products. RNAi, which is an abbreviation for RNA interference, is a technology that relies on gene regulation without the heritable effects on DNA. Because RNAi works downstream from DNA, it is not genetic modification and therefore is non-GMO. RNAgri has developed technology that will allow the cost-efficient production of RNA for topical RNAi uses in broad acre agriculture and in urban-structural pest control. Other high use rate applications for RNA such as for RNAi in aquaculture or animal husbandry could also benefit.

Our RNAi can be applied topically and requires no genetic modification, thus the effects of the RNAi are not heritable. It has potential to provide non-GMO traits in the field without actual genetic modification.

Previously, large scale fermentation processes were not viable because degradation of the RNA product in the microbe resulted in low yield and efficiency and thus high cost. RNAgri protects the RNA product, allows accumulation and can produce metric tons of RNA product.
ScalableTraditional large scale fermentation production is used to produce products such as proteins at tens of metric ton levels. RNAgri allows the use of these proven processes to create metric ton levels of RNA. The RNAgri approach has the potential to achieve metric ton levels of RNA at one dollar a gram or less.
RNAgri is a startup making huge progress in RNA production and RNAi products. RNAi, which is an abbreviation for RNA interference, is a technology that relies on gene regulation without the heritable effects on DNA. Because RNAi works downstream from DNA, it is not genetic modification and therefore is non-GMO. RNAgri has developed technology that will allow the cost-efficient production of RNA for topical RNAi uses in broad acre agriculture and in urban-structural pest control. Other high use rate applications for RNA such as for RNAi in aquaculture or animal husbandry could also benefit.
RNAi has potential to provide non-GMO traits in the field without genetic modification. RNAi is extremely specific and can provide very selective insect control without potential for off target effects; this opens up the potential for beneficial insects and improvements in biodiversity. This technology can reverse herbicide resistance in weeds and pesticide resistance in insects.
The agricultural traits and agricultural and urban and structural pest control businesses provide enormous value to society and generate billions of dollars in revenue for major agricultural companies. RNAi based products will provide complements and replacements for many current technologies and thus will create enormous value for agricultural companies and for society at large.
RNAgri has dependable third party validation of its Intellectual Property as well as unfettered freedom to operate. It is represented by a preeminent legal firm with a track record in biotech IP.
The following chart shows just some of the applications of RNAi across multiple industries.

Traits on demand

Spray on insect control in the field

Spray on virus control in the field

Ants

Termites

Cockroaches

Shrimp Virus

Sea lice in salmon farming
RNAgri is located in St. Louis, one of the premier agricultural science clusters in the United States. Our St. Louis location gives the company access to a world-class team of staff, directors and advisors. For more information about our dedicated and innovative team, visit our “Who We Are” page below.
RNA clay offers green alternative to plant pesticides (Eco-Business)
This Spray Can Silence Genes in Plants Without Changing Their DNA (Science Alert)
New RNAi spray formulation protects plants from viral infection for 20 days (Genetic Literacy Project)
RNAgri is seeking dedicated partners to help further develop our RNAi technology. Please visit our “Partnerships” page for more information about partnership opportunities.