All issues

Search results

IsoelectricPoint.pi() returns a pH where the net charge is far from zero

Status: Open.

#5312 In biopython/biopython;

· ChenziqiAdam opened on Sep 10, 2026

QCPSuperimposer returns a wrong rotation when the reference point set is collinear

Status: Open.

#5309 In biopython/biopython;

· ChenziqiAdam opened on Sep 10, 2026

Add ambiguous=... argument to GC() and GC123() for consistency with gc_fraction()

Status: Open.

#5307 In biopython/biopython;

· micheleoliveiracod opened on Sep 7, 2026

CodonAdaptationIndex.calculate() raises ZeroDivisionError for a valid CDS of only ATG/TGG codons

Status: Open.

#5306 In biopython/biopython;

· ChenziqiAdam opened on Sep 7, 2026

'importing Biopython from inside the source tree' false positives

Status: Open.

#5294 In biopython/biopython;

· jpintar opened on Aug 26, 2026

Bio.Seq.Seq ordering operators raise opaque TypeError instead of NotImplemented

Status: Open.

#5292 In biopython/biopython;

· AdvaitS opened on Aug 22, 2026

Incorrect reference handling in _arraycore initialization failure paths

Status: Open.

#5271 In biopython/biopython;

· stanbot8 opened on Aug 3, 2026

run_cealign segfaults on a zero fragment size, short coordinate entries, or tuples

Status: Open.

#5269 In biopython/biopython;

· dbolser opened on Jul 30, 2026

Proposition to add Radius of Gyration calculating function to Biopython

Status: Open.

#5257 In biopython/biopython;

· Grumb0t opened on Jul 7, 2026

Endian issue with binary CIF on ppc64 and sparc64 arch

Status: Open.

#5235 In biopython/biopython;

· schoekek opened on Jun 10, 2026

TLEN calculation when writing sam file

Enhancement

Status: Open.

Feature

#5232 In biopython/biopython;

· arzoopatel5 opened on Jun 3, 2026

PERF: SequentialSeqFileRandomAccess FASTA indexer does per-line regex on sequence lines

Status: Open.

#5197 In biopython/biopython;

· mmokrejs opened on Apr 17, 2026