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The issue is the missing reset. 2FF synchronizers need asynchronous reset. The reset must have a source, common to both clock domains, and it needs to have a synchronized release in each domain.
Fun story ...
A customer was complaining about IO's coming out of a chip they had produced, using a design I had worked with. The IO's worked well, and had the right output voltage (1.8v IIRC), unless they were driven with a 250MHz pattern--at which point the waveforms only