Immunotherapy plus chemotherapy cuts recurrence risk in dMMR stage III colon cancer
A landmark phase 3 trial reports major improvements for patients with deficient mismatch repair, with a large majority disease-free at 3 years—setting a new standard of care for this subgroup.
Immunotherapy plus chemotherapy cuts recurrence risk in dMMR stage III colon cancer
A landmark clinical development in colon cancer and a wave of new screening guidance both focus on outcomes—reducing recurrence and catching cancer earlier. Together, they signal a shift toward more precise, evidence-based cancer prevention and treatment for defined patient groups.
Figure of the Day
50% - Infant hospitalization risk reduction after COVID vaccination during pregnancy (first two months of life).
Next-gen gene therapy targets chronic pain—without opioids or addiction risk
Two breakthroughs target chronic pain and opioid avoidance, pointing to gene-therapy approaches that aim to change biology rather than mask symptoms. The focus is on long-term control with a clearer safety profile than traditional analgesics.
Pediatric flu vaccines substantially reduce emergency-care visits
Public-health and prevention studies span infectious disease and general health risk, from vaccination effects to population-level behavior. The unifying theme is measurable, clinically relevant endpoints that can inform policy and clinical practice.
Evidence says nicotine e-cigarettes beat patches and gum for quitting smoking
Attention turns to drugs and their safety tradeoffs, with evidence ranging from smoking cessation to harmful exposure trends. These items share a risk-reduction lens: what works, what doesn’t, and what demands stronger surveillance.
Yay
Artemis II astronauts arrive in Florida ahead of first moon trip in 53 years
NASA’s Artemis II crew has reached the launch site for the first crewed flyby to the Moon since Apollo—an important milestone for long-term lunar missions. More on phys.org
New Alzheimer’s drug target slashes brain plaques in early research
Several stories focus on Alzheimer’s and dementia, including mechanisms, targets, and early detection. Together they highlight an intensifying push from symptom management toward early biomarkers and pathway-driven therapies.
Brain scans link poor sleep to heightened negative emotions in alcohol addiction
Neurology and brain biology appear across multiple fronts, from addiction-related sleep mechanisms to memory circuits. The cluster theme is how brain activity and biological signals change with disease-relevant states, offering potential levers for treatment.
Nay
Surge in poisonings traced to a “gas station” drug
A once-niche herbal product has driven a steep rise in calls to poison centers, hospitalizations, and deaths—raising urgent public-health concerns. More on scitechdaily.com
Speed-of-processing brain training cuts dementia risk decades later
Neuroscience, cognition, and mental health meet large-scale social and economic forces, from dementia-risk interventions to loneliness trends. The common thread is measurable behavioral outcomes that matter at population scale.
Warmer coastal waters drive 50% to 64% of large-scale humid heat waves
Climate and environment attribution appear as both urgent hazards and longer-term system change—from extreme humid heat drivers to Arctic sea-ice signals. Together they connect near-term impacts with the physical mechanisms that explain them.
Quote
“A programme that offers scans to smokers between the ages of 55 and 74 detects a large number of early-stage…”
— Nature editorial summary
Scientists smash superconductivity record at normal pressure
Energy, materials, and carbon-management research cluster around performance and feasibility—new capture materials, superconductivity at practical conditions, and other pathways toward cleaner systems. The shared angle is progress from lab concepts toward scalable metrics.
Artemis II astronauts arrive in Florida ahead of the first moon trip in 53 years
Space exploration and deep-space science focus on mission milestones and observational advances, including a crewed lunar flight and new imagery of iconic targets. The cluster highlights both engineering progress and what those missions reveal about the solar system.
New enzyme atlas rewrites decades of biology research
Cancer, immunity, and advanced biology are complemented by platform-style advances in mapping and measurement—from enzyme atlases to body-wide cellular process methods. These developments aim to reduce knowledge bottlenecks by improving what scientists can observe and interpret.
AI wrote a scientific paper that passed peer review
AI, physics, and computation converge on fundamental verification and capability questions, including whether generative AI can pass peer review and how quantum limits affect devices. The unifying theme is measurement of reliability rather than hype.
Reddit
- Global human population has surpassed Earth’s sustainable carrying capacity. The Earth cannot sustain the future human…
- Covid-19 pandemic and vaccination has led to generation of widespread immunity against related sarbecoviruses, creating an…
- Women tended to cry more often than men. Women averaged nearly 6 crying episodes a month, while men averaged just under 3.…
- Agent Orange linked to aggressive bone marrow cancer in Vietnam veterans. American soldiers sprayed Agent Orange over the…
- By uncovering the earliest genetic evidence of domestic dogs to date, researchers have found that our 'best friends' were…
- Brain scans reveal how poor sleep fuels negative emotions in alcohol addiction
- A single dose of a new RNA based rabies vaccine given to puppies and kittens at 12weeks old provided complete protection…
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Scientific American
- Static electricity has baffled scientists for centuries. Can new research solve the puzzle?
- Can you survive inside a tornado? This scientist did by accident—he’s lucky to be alive
- How to build self-control, according to psychologists
- How ultraprecise ‘nuclear clocks’ could transform timekeeping
- How human neurons on a chip learned to play Doom
- NASA’s Artemis II astronauts arrive in Florida ahead of moon launch
- Trump’s new science panel includes 9 tech billionaires—and just one scientist
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New Scientist
- AI data centres can warm surrounding areas by up to 9.1°C
- I almost drowned in space when my helmet filled with water
- How Anthony Leggett pushed the boundaries of quantum physics
- We could protect Earth from dangerous asteroids using a huge magnet
- Author of Red Mars calls 'bullshit' on emigrating to the planet
- Why Kim Stanley Robinson's Red Mars is still a classic, 34 years on
- Read an extract from Kim Stanley Robinson's sci-fi classic Red Mars
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ScienceDaily
- New cholesterol guidelines could change when you get tested
- Scientists say the evidence is clear: E-cigarettes beat patches and gum in helping smokers quit
- This new therapy turns off pain without opioids or addiction
- This new carbon material could make carbon capture far more affordable
- After 20 years, scientists finally explain the Crab Pulsar’s strange “zebra stripes”
- Popular sugar substitute linked to brain damage and stroke risk
- Scientists discover why your appetite suddenly disappears when you’re sick
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Live Science
- Hubble images taken 25 years apart show big changes in the iconic Crab Nebula — Space photo of the week
- What would happen to Earth if the sun suddenly vanished?
- Top 5 health and fitness products to buy during spring sales (and 2 to skip)
- A gut microbe linked to the Mediterranean diet boosts muscle strength in mice
- Science news this week: NASA announces nuclear rocket, space reproduction proves difficult, and why weed gives you the munchies
- How to catch the full 'Pink Moon' in April followed by a 'Blue Moon' in May
- Why does cannabis give people 'the munchies'?
- More
Phys.org
- In wrangling dark matter, some scientists find inspiration in the Torah, Krishna and Christ
- Researchers examine how AI chatbots are shaping government operations
- How internal waves transport energy thousands of miles across the ocean
- Revealing the origin of polarity inversion in polymer semiconductors
- The Wired Belts are the new Rust Belts: Report ranks which jobs are most vulnerable
- Supercomputer simulations map spliceosome motions in a two-million-atom human cell model
- Clean energy subsidies mainly benefit high-income households, study finds
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Science Magazine News
- ‘Milestone’ research method measures gene activity across whole mice
- These birds suck—literally
- Jupiter’s weather forecast: cloudy with a chance of nukes
- These small African antelopes may help mpox spread
- Two years after it emerged, ‘cow flu’ is still circulating—and baffling scientists
- Long-standing volcanic eruption theory might be backward
- Abnormal behaviors in lab monkeys may reflect a lifetime of stressful experiences
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Nature News
- Huge lung-cancer screening campaign boosts early diagnosis
- Giants of the deep and the wonder of space: Books in Brief
- Eye drops made from pig semen deliver cancer treatment to mice
- Motherhood derails women’s academic careers — these data reveal how and why
- Briefing Chat: ‘Zombie cells’ resurrected with new genes
- Sunken Soviet nuclear submarine’s radioactive release
- Why labs need a napping room to help you work, rest and play
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Ars Technica Science
- Polygraphs have major flaws. Are there better options?
- Explanation for why we don't see two-foot-long dragonflies anymore fails
- Getting formal about quantum mechanics' lack of causality
- How new fishing tech can reduce bycatch of turtles and other creatures
- Rocket Report: Russia reopens gateway to ISS; Cape Canaveral hosts missile test
- Study: Sycophantic AI can undermine human judgment
- Damaged church floor may have revealed the grave of the fourth musketeer
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The Guardian – Science
- Full network of clitoral nerves mapped out for first time
- Down on your luck? How behavioural neuroscience could help
- Cambridge offers botany course that inspired Darwin after rare archive uncovered
- Brian Cox says physics faces ‘unquantifiable’ threat under punishing funding cuts
- Sperm get lost in space, Australian research into microgravity impacts suggests
- Church leaders criticise Christian owner of GB News over channel’s climate attacks
- Transporting the most expensive and volatile substance on Earth – podcast
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Science News
- How snakes defy gravity to stand tall
- Welcome to the weird world of AI agent teams
- A rare star in a tiny galaxy preserves a record of the early universe
- Watch the first video of a sperm whale birth captured by scientists
- Water has a newfound ‘critical point’ that may help explain its quirks
- Early apes may not have evolved in East Africa
- Social media can be addictive, a jury finds. Research hints at a link
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Quanta Magazine
The Scientist
- Postdoc Portrait: Thamires Magalhães
- Buntanetap: From Execution Poison to Potential Alzheimer’s Disease Drug
- Gut Inflammation Could Contribute to Multiple Sclerosis
- BiliSeq: A Molecular Test that Improves Bile Duct Cancer Detection
- H-1B Visa Restrictions Will Hurt America’s Research Potential, Experts Say
- AlphaFold Can Now Predict Protein Complex Structures at Scale
- Postdoc Portrait: Muneer Malla
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SciTechDaily
- Scientists Finally Capture Elusive Lipids in Action Inside Cells
- Scientists Track Bees in 3D and Discover Remarkable Secret Navigation Skills
- “Super Bizarre” – Neuroscientists Discover That Adult Brain Is Filled With Millions of “Silent Synapses”
- New Carbon Nanotube Coating Could Supercharge 6G Technology
- Scientists Smash Superconductivity Record at Normal Pressure
- 100x Less Power: The Breakthrough That Could Solve AI’s Massive Energy Crisis
- Simple Brain Training Cuts Dementia Risk Decades Later, Study Finds
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Sci.News
- Vitamin D Shows Promise in Resetting Immune System in Inflammatory Bowel Disease
- Ancient DNA Study Rewrites Origins of Europe’s First Dogs
- Webb and Hubble Telescopes Capture Saturn in Unprecedented Detail
- New Species of Steamer Duck Discovered in Chile
- Two Species of Marsupials Thought Lost for 6,000 Years Found Alive in New Guinea
- How Interstellar Comet 3I/ATLAS Met Unlikely Observer
- Two Protoplanets Emerge from Dusty Disk around Nearby Young Star
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