The Home of Midwood Science Research

Senior Research Student Shahzeen C.’s Project with the Natural Areas Conservancy

Posted on Saturday, March 28, 2026 by for Everyone.

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The Natural Areas Conservancy runs the Student Urban Nature (SUN) high school internship program through July and August of each year. This is a paid urban ecology program for rising junior and seniors in Queens or Staten Island. The internship is centered on fostering interest in science and nature by connecting students to their local natural area and its ecology.

Shahzeen Chowdhury is a senior at Midwood High School and a resident of Queens, who participated in the SUN program in summer 2023. She conducted a research project on trail maintenance and this experience helped inform her work on a high school research project on invasive plants. We had a chance to catch up with Shahzeen to hear about her reflections on the program and what’s next for her in the field of ecology!

What inspired you to join NAC’s SUN internship program?
SC: Upon seeing the flyer for NAC’s SUN internship program, I knew immediately that I wanted to be a part of it due to my passion for environmental conservation in urban areas. The opportunity to contribute to the preservation and enhancement of New York City’s natural areas, while gaining hands-on experience in both fieldwork and research, deeply resonated with my interests.

What research project did you conduct over the summer?
SC: As we collected various sorts of data, my group and I presented on the significance of trail management and maintenance. This included a history of NAC and their journey in restoring NYC’s natural areas, along with the complex foundation of Forest Park trails–including closing off “desire lines” and installing trail structures. We explained the functions and materials needed to build different trail structures, such as drainage dips, puncheons, and water bars. Additionally, we explored trail maintenance and restoration, soil decompaction, invasive species removal, and the closure of trails that served as party sites.

Our presentation ended with a proposal consisting of issues we observed, such as exposed tree roots and steepness, and fixes that include creating a “root bridge” and adding soil to address the steepness. We also suggested adding more garbage cans around the park by the trails and improving the signage around Forest Park. Another part of our research consisted of interviewing regular visitors of the park, in order to gain an understanding of their awareness of conservation methods. Based on our survey of 70 people at Forest Park, 80% were aware of the trail structures but only half of them knew the purpose they served.

How did this experience inform your research and science projects during the school year?
SC: This experience not only allowed me to gain insight into plant identification, learning to recognize species through the shapes of their leaves and other characteristics, but it also deepened my understanding of what goes into managing invasive plants. It taught me many valuable skills that I later applied in my research on how invasive plant species impact the abiotic factors of aquatic ecosystems. For example, I learned what makes a plant invasive, whether through its behavior in the environment or its origin. Additionally, I gained experience in the proper techniques for testing water pH, collecting samples, selecting sampling locations, and understanding various abiotic factors of water, such as sunlight and temperature.

Looking ahead into the future, what type of work or career path do you hope to take?
SC: As I begin a new chapter in my life, starting college, I’m hoping to continue conducting environmental research. Especially in opportunities that involve traveling abroad and dedicating time to focused projects. I look forward to building on my experiences with the Natural Areas Conservancy, engaging in both fieldwork and lab work!

Senior Looks for Breakthrough in Breast Cancer Research

Posted on Monday, December 23, 2024 by for Media.

Sukhdeep Kaur ‘25, working alongside Dr. Shaneen Singh at Brooklyn College Cancer Center and Ms. Susan Katzoff, is taking on groundbreaking protein research to combat cancerous mutations found in breast cancer.

Kaur's research, titled "CUL2 and BRCA1 Interactions Through PRAME in NCL," studies how BRCA1 (Breast Cancer Gene 1) aids in DNA repair and stops cells from multiplying and dividing too swiftly — something that can lead to cancer. Kaur is trying to target PRAME, a harmful protein that prevents the body from getting rid of abnormal or unneeded cells, and NCL (nucleolin), another protein that is overexpressed in breast cancer tissue.

She initially concentrated on investigating how BRCA1 and CUL2 (a protein that helps prevent uncontrolled cell proliferation) interacted. However, in the lab, she quickly discovered that BRCA1 and CUL2 did not directly interact. Through mapping, literature analysis, and studying the proteins' subnetworks, she discovered that they interacted through PRAME, so she expanded her research.

Teacher and student
Ms. Katzoff and Sukhdeep Kaur '25 display a model of Kaur's research. Photo: Nathanaelle Joseph and Han Xin Ou Yang

Kaur's inspiration for this project comes from her teachers and family members. "My grandma had breast cancer, so it was nice to understand what she experienced on a molecular level," Kaur said. "There is not much treatment related to cancer, and even less when it comes to women's health."

"I would also like to shout out Mr. [Glenn] Elert, who got me into the lab," she added. "He inspired me to keep doing research and carry it into senior year."

Her project has used many bioinformatic tools and literature resources to help model the docking proteins. Currently, Kaur has found a model of PRAME that she is using to try and dock it with CUL2 to find the interactors.

Kaur meets with her Brooklyn College professors once a week over Zoom to discuss the project and formulate questions.

"Initially, walking in and being with graduate students and undergraduates was overwhelming," Kaur said. "But now I've gotten the hang of it."

As Kaur furthers her education, she hopes to "expand her research to greater heights" by working with experienced professionals in pharmaceuticals and therapeutic treatments.

Kaur is a part of the Midwood Science Research Program, a three year course offered to Medical Science students, preparing them to design and conduct experiments from their sophomore year on. They also learn real world skills such as writing cover letters and contacting college professors.

"Inquiry investigations, writing resumes, writing scientific research proposals, and designing procedures for experimentation are all paramount to success in the Midwood Science Research Program," said Ms. Katzoff.

Ms Katzoff has been teaching research at Midwood for seven years She took over Mr. Elert's workload upon his retirement in September. "When I took on Sukhdeep, she was at the data collection and analysis stage of her project," said Ms. Katzoff. "We primarily discussed the output that she was getting from databases and creating the PRAME protein."

Throughout the duration of her project, Kaur has faced many setbacks. "It can be challenging to find accurate information when using many models and data," she said. "One program might deviate from the others a lot, so it is hard to come to a consensus on what might accurately reflect the model."

Kaur is taking AP Biology and was able to apply concepts like DNA replication and genetic information from her class to her research.

"It is an honor and a privilege to learn new information from students," said Ms. Katzoff. "And it's very rewarding to work with research students because they become the experts in the field, and the direction of learning shifts."

Kaur will soon display her project for the first time in the Junior Science and Humanities Symposium (JSHS) and Regeneron Science Talent Search (STS).

"Ms. Katzoff has been really motivating me to meet the deadlines for all competitions and to continue the second round of experiments," said Kaur.

To aspiring researchers, Ms. Katzoff said, "Follow your heart and choose a topic you're passionate about so that your project has the force to be successful in this program and in life."

Kaur added, "Science is always about questioning, so keep questioning everything you see."

Written by Nathanaelle Joseph and Han Xin Ou Yang (Class of 2025)
This article originally appeared in the online version of Argus on December 13, 2024.

Alumni Anne Li published in International Journal of Radiation Oncology

Posted on Monday, September 30, 2024 by for Publications.

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Anne Li (class of 2022) has been published in the International Journal of Radiation Oncology with her study End of Treatment Monocyte and Lymphocyte Counts Predict for Survival over Three Years in Patients with Glioblastoma Treated with Conventional Radiation that she conducted as a Junior Neuroscience student at Johns Hopkins University. Anne presented this work at the 66th Annual Meeting of the American Society of Radiation Oncology (ASTRO).

The research examines the changes in leukocytes (White Blood Cells) over the course of a 6 week radiation treatment for patients diagnosed with Glioblastoma, the most commonly diagnosed primary brain cancer. As White Blood Cells are important in the anti-neoplastic immune response, subtypes including lymphocytes and monocytes (a myeloid derived cell) have been identified as promoting tumor suppression and tumor progression in its opposite nature.

Since radiation is cytotoxic and does not discriminate against healthy WBCs; we examined these changes pre and post RT and found that elevated monocyte counts >600 and lower lymphocyte counts <800 were prognostic factors that indicated lower disease survival.

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Midwood Science Research, Class of 2024

Posted on Friday, June 21, 2024 by for Seniors.

Large group photo in the Midwood Auditorium

2024 Midwood Science Fair Awards

Posted on Friday, June 7, 2024 by for Awards, Science Fair.

And the winners are…

1st Place

Traditional photo of the award winner holding their trophy standing in front of their poster board
Vivian Li
Acid Rocks
Traditional photo of the award winner holding their trophy standing in front of their poster board
Akash van Koert & Alexandra Rakhovski
Berry Badness

2nd Place

Traditional photo of the award winner holding their trophy standing in front of their poster board
Aziza Ziyadulloeva & Kathy Liang
Water Quality on Marine Life
Traditional photo of the award winner holding their trophy standing in front of their poster board
Han Xin Ou Yang & Abril Flores
The investigation of amylase enzyme digestion time on the production of reduced sugar in various fruits and vegetables

3rd Place

Traditional photo of the award winner holding their trophy standing in front of their poster board
Meerab Chishty & Mariam Gvasalia
Investigating the Effect of Sucrose and Glucose on Tooth Enamel Decay

Honorable Mention

Traditional photo of the award winner holding their trophy standing in front of their poster board
Timothy Wong
Investigating the Influence of Sunlight on Mitosis Rate in Amoeba Proteus
Traditional photo of the award winner holding their trophy standing in front of their poster board
Hafsa Fnu & Sophia Ugazovas
Spray Away: The Effect of Different Disinfectant Spray Brands on Bacterial Growth on Doorknobs
Traditional photo of the award winner holding their trophy standing in front of their poster board
Lena Li & Saba Khoja
Comparing the efficiency of various antacid brands on neutralizing pH levels of stomach acid
Traditional photo of the award winner holding their trophy standing in front of their poster board
Leo Ye & Ivan Chen
Investigating Soil Liquefaction and its Impact on Earthquake-Prone Areas
Traditional photo of the award winner holding their trophy standing in front of their poster board
Queeny Huang & Sanna Ngo
Mindful for Math
Traditional photo of the award winner holding their trophy standing in front of their poster board
Kathryn Otkydach & Luis Olvera
Investigating the Relationship Between Body Mass and Impact Force in Falls on Different Materials

Bonus photo

Group photo of all the winners holding their trophies
Congrats to all the winners!

Alumni Spotlight: Christopher Ayala (Class of 2014)

Posted on Friday, June 7, 2024 by for Alumni Spotlight.

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Selfie of Chris Ayala

Chris Ayala is an alumni of the Midwood Science Research program who worked on the project "Encoding Information with Light's Angular Momentum" with Dr. Giovanni Milione. He graduated in 2014, and since then, has continued his interest in research as a PhD candidate at the University of Michigan. He's currently the President of the Society of Hispanic Professional Engineers (SHPE) and the Vice President of the National Society of Black Physicists (NSBP). Aside from his passion for physics, Ayala enjoys scuba diving and drone photography in his free time. He also loves to cuddle his cat-daughter Kyoshi. I got the opportunity to interview him and see what he's been up to these past 10 years and what advice he has for current students in the research program.

Masha: What did you do during your time as a part of Science Research?

Chris: To encompass what I've done during my time at Midwood Science Research was build a really solid understanding of what I liked and did not like about research.There was a sophomore science research class in which we were able to partake in research projects that we were able to think of ourselves and that helped [kindle] my beginning interest in science research. It wasn't until the summer of sophomore year where I asked Mr. Elert what other options there were to keep my summer occupied. He had given me a connection to a PhD student he knew at City College University. I think just that experience alone helped determine that what I wanted to do was to study lasers.

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Chukwunonso Nwasike, Akeem Pinnock, and Chris Ayala at the 2014 National ACT-SO

After successfully completing two Bachelor's degrees in Applied Mathematics and Physics at SUNY Stony Brook, Ayala continued his studies at the University of Michigan, but not before taking an opportunity that would further his interests even more.

Chris: I took a gap year after I graduated and deferred my acceptance to the University of Michigan where I worked in the meantime at the University of Witwatersrand in South Africa for a year, working on quantum imaging research for a year. After that I came back and started my PhD at the University of Michigan, where I currently am a 5th year PhD candidate working for the Steven Cundiff Research Lab.

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Chris's experimental setup

Masha: What would your PhD specifically be in?

Chris: My PhD specifically focuses on the study of interaction of light — mostly visible light, up to infrared — and the interaction of semiconductor materials which are used in your everyday electronics, specifically wide gap materials. Then, that produces high harmonic generation, which is a process which produces higher frequency light after the interaction with the semiconductor metal. So, I'm effectively taking visible light and then changing its frequency to ultraviolet.

Masha: What do you like most about what you do?

Chris: I get to shoot lasers and play with lasers. I think that really hasn't changed from when Mr. Elert asked me that as a sophomore in high school. He asked, "Do you want to work with this PhD student who works with lasers?" and as a 14 year old kid, I said, "Yes please!" Now I find myself as a "semi expert in the field of lasers."

Masha: Did you ever encounter any difficulties throughout your career?

Chris: Yeah. As an experimentalist, one of the biggest issues you really face is your own experimental setup. Many of my issues have mainly been due to laser error, but, I think, in the long run, these issues have also — in a twist of fate — helped me understand the laser better and my foundational knowledge of it. But, overall, the main challenge of it has been a little bit of motivation in trying to get these things to work and being in school for so long.

If you would like to read more about Chris's favorite memories of Science Research or other advice he has for students, click here to read a transcript of the full interview.

Masha Bazilevich (Class of 2024)

24/7 Lecture: Identity development in adolescents

Posted on Wednesday, June 5, 2024 by for 24/7 Lecture.

24 seconds: This project explores the influence of different individuals on the identity development of adolescents. After analyzing responses from 108 surveyed students, parents emerged to be the most influential, followed by friends and grandparents. Additionally, conducting a statistical analysis using paired sample t-tests revealed the importance of parental figures in shaping adolescent identity and self-perception.

7 Words: Parents carve, friends polish, and others shadow.

Areeba (Class of 2024)

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24/7 Lecture: Researching the mechanisms of actions of 5-fluorouracil in wild-type and ThyA Escherichia coli

Posted on Tuesday, June 4, 2024 by for 24/7 Lecture.

This 24/7 Lecture is also available on Instagram.

24 seconds: 5-Fluorouracil (5-FU) is a chemotherapy drug used to treat various cancers by inhibiting thymidylate synthetase (TS), essential for DNA synthesis. Our research focused on its mechanisms in wild-type and ThyA mutants of E. coli. We found that minimal thymidine is required for bacterial growth, and deoxyuridine inhibits ThyA mutants while enhancing 5-FU's effectiveness. Additionally, ThyA mutants needed less thymidine than CarAB.

7 words: Investigating properties of 5-FU on Escherichia coli.

Rikza, Devin, Joanne (Class of 2024)

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24/7 Lecture: The correlation between emojis and communication interpretation

Posted on Monday, June 3, 2024 by for 24/7 Lecture.

This 24/7 Lecture is also available on Instagram.

24 seconds: Two different forms of survey were sent out. One form of the survey had five conversations with emojis present and the other form of survey had five conversations without emojis present. After reading the conversations the participants were asked to rate on a scale from 1–5 about how positive they think the conversation was. Then the participants were asked questions about how they perceived the person's feelings. Both forms of the survey were compared using bar graphs and regression analysis.

7 words: Use emojis and make communication more meaningful.

Sanbina (Class of 2024)

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24/7 Lecture: The sun’s magnetic activity: Statistics of solar flare and sunspot numbers

Posted on Sunday, June 2, 2024 by for 24/7 Lecture.

This 24/7 Lecture is also available on Instagram.

24 seconds: I used Anaconda, a coding platform that enabled me to use Python. Using Spyder in Anaconda, I used programming packages like Numpy and Matplotlib to analyze data on the intensity of solar flares, the number of solar flares, and the number of sunspots. My mentor provided all the data and taught me how to navigate Spyder to create multiple graphs to analyze the relationship between solar flares and sunspots.

7 words: Analyzing relationships between sunspots and solar flares.

Emely (Class of 2024)

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24/7 Lecture: Why your favorite lipstick shade may not match your personal color

Posted on Monday, May 27, 2024 by for 24/7 Lecture.

24 seconds: Individuals often struggle when selecting cosmetic palettes that best match their personal colors. This experiment examines the impact of wearing the right arrangement of colors on attractiveness. By applying different shades of lipsticks on individuals with varying undertones, data shows a correlation between undertones and suitable colors for those with neutral or warm undertones, but not for those with cool undertones.

7 words: Save your money on personal color analysis.

Xinwei (Class of 2024)

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2024 Science Fair on News12

Posted on Friday, May 24, 2024 by for Media, Science Fair.

View this post on Instagram

A post shared by Midwood Science (@midwoodscience)

2024 Science Fair Abstract Book (and more from the past)

Posted on Wednesday, May 22, 2024 by for Science Fair.

2024 abstract book cover
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24/7 Lecture: Testing methods for identifying and analyzing circumstellar disk structures

Posted on Wednesday, May 22, 2024 by for 24/7 Lecture.

This 24/7 Lecture is also available on Instagram.

24 seconds: Protoplanets are typically found within circumstellar disks where they cast shadows. Our project utilizes scattered light data taken from multiple imaging instruments based on the criteria of having previously confirmed shadows. We utilized Python to deproject these images, apply an r2 correction, and made profiles to construct Normalized Intensity vs. Azimuth and Radius vs. Azimuth graphs to identify shadows and compare these results to those from previous literature.

7 words: Planets forming cast shadows. We analyze shadows.

Ava and Zehra (Class of 2024)

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24/7 Lecture: The effects of omega 3 fatty acids on suppressing ADHD symptoms

Posted on Tuesday, May 14, 2024 by for 24/7 Lecture.

For a video with more information on this project see our Instagram feed.

24 seconds: Attention deficit hyperactivity disorder is a chronic condition that affects children all around the US. This is an attempt to understand if omega-3 fatty acids are an effective way to suppress ADHD symptoms using meta-analytical techniques. Greater consumption of EPA and DHA were seen to lead to a greater chance of reducing ADHD symptoms as a longer duration of the experiment indicates.

7 words: Natural medication for the suppression of ADHD.

Yanhe and Joey (Class of 2024)

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24/7 Lecture: Evidence for the ability of horses to read human emotions

Posted on Sunday, May 12, 2024 by for 24/7 Lecture.

This 24/7 Lecture is also available on Instagram.

24 seconds: 17 horses were each shown 3 photos; one of a smiling, one of an angry, and one of a sad woman. Horses express body language through putting down their head, reaching toward something, pinning ears, and left-gaze bias. They were shown the photos, and anytime they did those cues, it was recorded. Most horses responded in an expected way – the angry and sad photo caused responses associated with negative horse emotions such as pinning ears and left-gaze bias, while the happy photo caused most horses to reach toward it, which is a sign of comfort. For this reason, it’s possible to say that horses can read human emotions.

7 words: Did you know horses read human emotions?

Hamood (Class of 2024)

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