Jekyll2022-05-20T01:05:51-04:00https://simozacca.github.io/feed.xmlSimone ZaccariaGroup leader of Computational Cancer Genomics lab at UCL Cancer InstituteSimone Zaccarias.zaccaria@ucl.ac.ukCHISEL is published in Nature Biotechnology!2020-09-02T00:00:00-04:002020-09-02T00:00:00-04:00https://simozacca.github.io/posts/2020/09/chisel<h1 id="description">Description</h1>
<p>CHISEL has been published in <em>Nature Biotechnology</em> at: https://www.nature.com/articles/s41587-020-0661-6.
CHISEL (Copy-number Haplotype Inference in Single-cells using Evolutionary Links) is a method to infer allele- and haplotype-specific copy numbers in single cells and subpopulations of cells by aggregating sparse signal across hundreds or thousands of individual cells.
CHISEL is available on GitHub at https://github.com/raphael-group/chisel.</p>Simone Zaccarias.zaccaria@ucl.ac.ukDescriptionHATCHet is published in Nat Commun!2020-09-02T00:00:00-04:002020-09-02T00:00:00-04:00https://simozacca.github.io/posts/2020/02/hatchet-natcomm<h1 id="description">Description</h1>
<p>HATCHet has been published in <em>Nature Communications</em> at: https://www.nature.com/articles/s41467-020-17967-y.
HATCHet (Holistic Allele-specific Tumor Copy-number Heterogeneity) is an algorithm that infers allele- and clone-specific CNAs and WGDs jointly across multiple tumor samples from the same patient.
HATCHet is available on GitHub at https://github.com/raphael-group/hatchet.</p>Simone Zaccarias.zaccaria@ucl.ac.ukDescriptionHATCHet is out!2018-12-17T00:00:00-05:002018-12-17T00:00:00-05:00https://simozacca.github.io/posts/2018/12/hatchet<h1 id="description">Description</h1>
<p>Our new method to infer copy-number aberrations and whole-genome duplications jointly from multiple tumor samples is out! Check out the corresponding <a href="https://www.biorxiv.org/content/10.1101/496174v1">manuscript</a> and try HATCHet available on <a href="https://github.com/raphael-group/hatchet">github</a>.</p>Simone Zaccarias.zaccaria@ucl.ac.ukDescriptionSimone postdoc at Princeton University2017-04-20T00:00:00-04:002017-04-20T00:00:00-04:00https://simozacca.github.io/posts/2017/04/postdoc<h1 id="description">Description</h1>
<p>Simone officially starts a postdoc at Princeton University in the group of Prof. Ben Raphael.</p>Simone Zaccarias.zaccaria@ucl.ac.ukDescription