Find and delete/change registry entry with powershell

You can do it as follows:

$Registry_Key = "HKLM:\SOFTWARE\Wow6432Node\Lenovo\Access Connections\Locations\*\*\*"
Get-ItemProperty -path $Registry_Key -name m_bSetBrowserPxySettings -ErrorAction SilentlyContinue | % { Set-ItemProperty -path $_.PSPath -name m_bSetBrowserPxySettings "0" }

You need pipe the Get-ItemProperty command to:

% { Set-ItemProperty -path $_.PSPath -name m_bSetBrowserPxySettings "0" }

% represents the ForEach-Object cmdlet. What it will do is iterate over each item in the collection you get out of the Get-ItemProperty command. $_ represents the object in the pipeline, so this will change to the new item on each iteration.

$_.PSPath is the path to the registry key of the item. You can see this printed in the table in your question. You can use this value to pass to Set-ItemProperty along with your name and then set the value to whatever you want.

If you wanted to remove the item altogether, pipe to the following instead:

% { Remove-ItemProperty -path $_.PSPath -name m_bSetBrowserPxySettings }

Rather than working with the path all the time you can just work on the item itself:

$Registry_Key = "HKLM:\SOFTWARE\Wow6432Node\Lenovo\Access Connections\Locations\*\*\*"
$item = Get-Item $Registry_Key
$item | Get-ItemProperty -name m_bSetBrowserPxySettings -ErrorAction SilentlyContinue

Then to set it to 0:

$item | Set-ItemProperty -name m_bSetBrowserPxySettings "0" 

Or to delete it:

$item | Remove-ItemProperty -name m_bSetBrowserPxySettings