Closing an Excel File Using Python Last Updated : 23 Jul, 2025 Comments Improve Suggest changes 13 Likes Like Report We are given an excel file that is opened and our task is to close that excel file using different approaches in Python. In this article, we will explore three different approaches to Closing Excel in Python. Closing an Excel Session with PythonBelow are the possible approaches to Using Os In Python For Closing Excel: Using win32comUsing os.system with taskkill.Using psutil.Note: The Excel application should be opened before performing all the below executions. Closing Excel in Python Using win32comIn this example, we are using the win32com library in Python to interact with Microsoft Excel. The code creates an instance of the Excel application using the Dispatch function and subsequently closes the Excel application by invoking the Quit() method. This allows for programmatic control and closure of Excel through Python. Python3 import win32com.client excel = win32com.client.Dispatch("Excel.Application") excel.Quit() print("Excel closed using win32com") Output: Closing Excel Using os.system with taskkillIn this example, we are using the os.system function in Python to execute a command-line instruction to forcefully terminate the Excel process. The command taskkill /f /im excel.exe kills all instances of Excel (excel.exe) forcefully (/f). The print statement indicates that Excel has been terminated using the taskkill command. Python3 import os os.system("taskkill /f /im excel.exe") print("Excel terminated using taskkill") Output: Closing Excel Using psutilIn this example, we are using the psutil module in Python to iterate through the running processes. When a process with the name "EXCEL.EXE" is found, the kill() method is called to terminate the Excel process. The print statement indicates that Excel has been closed using the psutil module. Python3 import psutil for proc in psutil.process_iter(): if proc.name() == "EXCEL.EXE": proc.kill() print("Excel closed using psutil") Output: Create Quiz Comment V vishnuvardhan1510 Follow 13 Improve V vishnuvardhan1510 Follow 13 Improve Article Tags : Python Python Programs python-os-module Python-excel Explore Python FundamentalsPython Introduction 2 min read Input and Output in Python 4 min read Python Variables 4 min read Python Operators 4 min read Python Keywords 2 min read Python Data Types 8 min read Conditional Statements in Python 3 min read Loops in Python - For, While and Nested Loops 5 min read Python Functions 5 min read Recursion in Python 4 min read Python Lambda Functions 5 min read Python Data StructuresPython String 5 min read Python Lists 4 min read Python Tuples 4 min read Python Dictionary 3 min read Python Sets 6 min read Python Arrays 7 min read List Comprehension in Python 4 min read Advanced PythonPython OOP Concepts 11 min read Python Exception Handling 5 min read File Handling in Python 4 min read Python Database Tutorial 4 min read Python MongoDB Tutorial 3 min read Python MySQL 9 min read Python Packages 10 min read Python Modules 3 min read Python DSA Libraries 15 min read List of Python GUI Library and Packages 3 min read Data Science with PythonNumPy Tutorial - Python Library 3 min read Pandas Tutorial 4 min read Matplotlib Tutorial 5 min read Python Seaborn Tutorial 3 min read StatsModel Library - Tutorial 3 min read Learning Model Building in Scikit-learn 6 min read TensorFlow Tutorial 2 min read PyTorch Tutorial 6 min read Web Development with PythonFlask Tutorial 8 min read Django Tutorial | Learn Django Framework 7 min read Django ORM - Inserting, Updating & Deleting Data 4 min read Templating With Jinja2 in Flask 6 min read Django Templates 5 min read Build a REST API using Flask - Python 3 min read Building a Simple API with Django REST Framework 3 min read Python PracticePython Quiz 1 min read Python Coding Practice 1 min read Python Interview Questions and Answers 15+ min read Like