PhD Candidate in Biological Sciences/Computer Science,                    Associate Fellow of Higher Education Academy (UK)

Yi-Hsuan Lee 李毅軒 Official: Instagram | Linktree

Yi-Hsuan Lee is a passionate bioinformatician / computational biologist specialising in bioinformatics and applied research. With a strong academic background and hands-on experience, he develops and analyses complex biological and medical diagnostic data using a wide range of bioinformatics tools. He brings strong communication and problem-solving skills to multidisciplinary research, bridging computational analysis with real-world biological/medical questions, particularly in host-microbiome interactions, infection dynamics, and gene transfer mechanisms. He is a member of the British Society for Parasitology (BSP) and an Associate Fellow of the Higher Education Academy(AFHEA) (UK).

李毅軒是一位充滿熱情的生物資訊學家/計算生物學家，專注於生物資訊學和應用研究。憑藉著深厚的學術背景和豐富的實務經驗，他能夠使用各種生物資訊工具開發和分析複雜的生物和醫學診斷數據。他將強大的溝通能力和解決問題的能力融入跨學科研究中，將計算分析與現實世界的生物/醫學問題聯繫起來，尤其是在宿主與微生物之間的互動關係、感染動力學和基因轉移機制方面。他是英國寄生蟲學會 (BSP) 的會員，也是英國高等教育學院副院士(AFHEA)。

Biography 個人簡介

Bioinformatics 生物資訊學

Infectious Diseases 傳染疾病

Microbial ecology 微生物生態學

Microbiome 微生物群

Transposable Elements (TE) 轉座子

Horizontal Gene Transfer (HGT) 水平基因轉移

Antimicrobial Resistance (AMR) 抗生素抗藥性

Areas of expertise 專業領域

Yi-Hsuan Lee graduated from Tzu Chi University (Taiwan) with a BEc in Medical Informatics. He then completed an MSc in Applied Bioinformatics at Cranfield University (UK) and is currently studying for a PhD in Biological Sciences/Computer Science at Aberystwyth University (UK).
                                                                     

李毅軒畢業於台灣慈濟大學，取得醫學資訊學學士學位。其後，他於英國克蘭菲爾德大學取得應用生物資訊學碩士學位，目前正在英國亞伯里斯威爾大學（亞伯大學）攻讀生物科學/電腦科學博士學位。

Education background 教育背景

His research focuses on Schistosomiasis, Bovine Tuberculosis (bTB, Infected humans or animals), and the role of transposon and Horizontal Gene Transfer (HGT) in the gut microbiome. He aims to elucidate how infections, particularly S. mansoni and M. bovis, influence gut microbial communities, with a special focus on:
•Alterations in gut microbial communities associated with infection and their impact on microbial diversity and function.
•HGT-driven genomic changes, particularly the transfer of insertion sequence (IS) elements.
•The spread of antimicrobial resistance (AMR) genes within the gut microbiome.
•The interplay between microbial ecology, host-microbiome interactions, and gene transfer mechanisms in infection dynamics.

他的研究著重於血吸蟲病、牛結核病 (bTB, 感染人類或動物) 以及水平基因轉移 (HGT) 在腸道微生物群中的作用。 他的目標是闡明感染（尤其是曼氏血吸蟲和牛分枝桿菌）如何影響腸道微生物群落，特別著重於以下幾點：
•與感染相關的腸道微生物群落的改變及其對微生物多樣性和功能的影響
•水平基因轉移 (HGT) 驅動的基因組變化，尤其是插入序列 (IS) 的轉移
•抗生素抗藥性 (AMR) 基因在腸道微生物群內的傳播
•微生物生態學、宿主與微生物之間的互動關係，以及感染動態中的基因轉移機制

Recent Research 近期研究

ORCID

Google Scholar

Blog

Publiaction 期刊論文

Biochar-Induced Microbial Shifts: Advancing Soil Sustainability

Use of a cytochrome P450 humanised mouse model to refine schistosomiasis drug discovery

Yi-Hsuan Lee 李毅軒

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Yi-Hsuan Lee 李毅軒

PhD Candidate in Biological Sciences/Computer Science, Associate Fellow of Higher Education Academy (UK)

Publiaction 期刊論文

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