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Current Medicinal Chemistry

Journal Impact Factor: 3.5
Scopus Cite Score: 7.7

Indexed in: Scopus, SCI Expanded, MEDLINE/PubMed

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Aims and Scope:
Current Medicinal Chemistry covers all the latest and outstanding developments in the field of medicinal chemistry. It also includes topics related to quantitative structure-function relationships, drug absorption, drug distribution, drug metabolism, new and emerging drug targets, pharmacogenomics, drug discovery toxicology, high-throughput screening, combinatorial chemistry, structural characterization and organic syntheses of naturally occurring compounds, as well as chemical and analytical techniques used in rational drug design. Each issue incorporates a series of timely in-depth/mini-reviews and guest-edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents.
Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be informed and up-to-date with the latest and most important developments relevant to their field.
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Editor-in-Chief:

  • Atta-ur-Rahman, FRSHonorary Life Fellow
    King’s College
    University of Cambridge
    Cambridge
    United Kingdom

ISSN: 0929-8673 (Print)

eISSN: 1875-533X (Online)

Special Issues With Active Call for Papers

Submission closes on: May 14, 2027
Artificial Intelligence Empowers the Research and Development of Anti-Infective Drugs: From Target Discovery and Molecular Design to Clinical Translation

The global crisis of drug resistance in bacteria, viruses, fungi, and parasites is becoming increasingly severe. Traditional anti-infective drug development faces bottlenecks such as long cycles, high costs, low success rates, and a shortage of novel structures. Artificial intelligence (AI) and machine learning are fundamentally reshaping the drug discovery and development chain, demonstrating disruptive value in target mining, virtual screening, de novo design, druggability optimization, resistance mechanism prediction, and clinical translation. This special issue focuses... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Shenghua Gao
Co-Guest Editor(s): Shujing Xu,Haiyong Jia,Xiangyi Jiang,Peng Zhan
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Submission closes on: Apr 22, 2027
Tumorigenesis, tumor development, and tumor treatment

Cancer remains a leading global health challenge, demanding continuous advances in understanding its origins and improving therapeutic strategies. This thematic issue focuses on the fundamental biological processes driving cancer, from initial tumorigenesis through progression and metastasis, to the development and application of novel treatments. We seek contributions exploring the molecular and cellular mechanisms underlying oncogenesis (genetic mutations, epigenetic alterations, signaling pathways), tumor development (microenvironment interactions, angiogenesis, immune evasion, metastasis), and the translation of this knowledge... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Tianyu Cao
Co-Guest Editor(s): Tao Yang
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Submission closes on: Mar 13, 2027
Advances in Computational Strategies for Neurodegenerative Disorders, Cancer, and Infectious Diseases”

This thematic issue highlights recent advances in computational strategies applied to neurodegenerative disorders, cancer, and infectious diseases. It focuses on the use of artificial intelligence, machine learning, molecular modeling, molecular dynamics simulations, bioinformatics, and multi-omics data analysis to understand disease mechanisms and accelerate drug discovery. The contributions demonstrate how computational approaches enable target identification, prediction of drug–target interactions, biomarker discovery, and optimization of therapeutic candidates. By integrating computational tools with experimental and clinical research, this... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Ali Irfan
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Submission closes on: Feb 21, 2027
Precision Medicine and Translational Innovation in Cutaneous-Musculoskeletal Biology: Mechanisms, Biomaterials and Clinical Translation

This thematic issue focuses on cutaneous and musculoskeletal tissue biology, spanning traumatic repair, pathological disorders, and regenerative medicine across both systems. We welcome original studies integrating epidemiological analysis, disease prediction models, multi-omics integration, genetic dissection, virtual cell technology, organoid models, advanced biomaterials, clinical efficacy evaluation, and pharmacological mechanism research to unravel underlying mechanisms and develop innovative therapeutic strategies. Papers will bridge bench-to-bedside translation, addressing unmet clinical needs in wound healing, musculoskeletal disorders, and tissue regeneration,... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Peng Wang
Co-Guest Editor(s): Jinfu Li,Zexin Zhang
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Submission closes on: Feb 18, 2027
Advance in Novel Drug and combined Therapies for Chronic Diseases

Chronic diseases such as malignant tumors and rheumatoid arthritis have long plagued a large number of patients. Currently, the management of chronic diseases has entered a new stage of targeted regulation, precise intervention and integrated treatment. The traditional diagnosis and treatment model is undergoing profound changes due to new drugs and intelligent combined strategies. The core goal is to achieve long-term stable control of the disease and improve the quality of life of patients. The... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Shigao Huang
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Submission closes on: Jan 07, 2027
Current concepts in the study of new therapeutic targets and the development of drugs for diseases of the central nervous system

Central nervous system (CNS) diseases are among the leading causes of chronic disability and mortality worldwide. According to the World Health Organization (WHO), neurological disorders affect over 1 billion people, and the cost of their treatment increases annually. However, advances in neuroscience and medicine are enabling fundamentally new approaches to treating CNS diseases. Modern approaches to CNS drug development include personalized medicine based on genetics, targeted molecular targeting using advanced technologies such as genetic engineering,... see more

Impact Factor: 3.5
Guest Editor(s): Dr. Ilgiz F. Gareev
Co-Guest Editor(s): Vladimir Chekhonin
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Submission closes on: Oct 03, 2026
Sustainable Molecular Design for Health and Economy: New Directions in Medicinal Chemistry

The evolving landscape of medicinal chemistry is increasingly influenced by the urgent need to reconcile human health priorities with sustainability imperatives and economic feasibility. While drug discovery and therapeutic development pipelines lead to substantive scientific outcomes, they nonetheless remain disproportionately resource-intensive, environmentally taxing, and financially enclosed. In response to these requirements, this themed issue entitled "Sustainable Molecular Design for Health and Economy: New Directions in Medicinal Chemistry" offers a collection of works intended to showcase... see more

Impact Factor: 3.5
Guest Editor(s): Dr. DIVYA TRIPATHY
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