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Codex for non-technical people 👇 What have you been building with Codex?

Lauren Bannon, who runs a marketing business and raises two daughters, credits ChatGPT for saving her life after an illness that couldn’t be diagnosed. In February 2024, she started waking up with hands that did not work the way they always had. Her pinky fingers “weren’t bending in the morning and night.” Before long she was also experiencing heart palpitations and a reflux-like sensation when she leaned down. An X-ray came back normal. A rheumatology specialist labeled it seronegative rheumatoid arthritis and prescribed medication, yet Bannon hesitated. “I have never been sick,” she told her husband, and she felt she was too young for arthritis to make sense. She could not shake the sense that something was being missed. For many months, she tried to push through. But by September, she was hit with excruciating stomach pain, a relentless burning that left her surviving off toast and water. A gastrointestinal scope showed inflammation and she was put on proton pump inhibitors, but the inflammation just wouldn’t stop. At home, often late at night, Bannon turned to ChatGPT, a tool she already used for her work in marketing, even though her husband thought she was crazy for talking to a computer. She began entering her symptoms and blood results, looking for patterns across months of data that no single appointment could easily address. When she asked, “what mimics rheumatoid arthritis?” ChatGPT pointed her toward Hashimoto’s disease, an autoimmune thyroid condition where the body attacks itself. ChatGPT urged a specific next step: “Get your doctor to test your TPO level,” referring to a thyroid antibody. Her clinician initially pushed back, because Lauren’s other thyroid labs were normal, but armed with her knowledge and desperate for real answers, Bannon pushed harder. “I need to know what’s going on with me,” she told her doctor. “I want to test it.” The thyroid peroxidase antibody result came back elevated at 220, roughly six times normal levels, confirming an auto-immune condition like Hashimoto’s and leading her to an endocrinologist. From there, a neck scan revealed two lumps, and a biopsy confirmed they were cancer, including an aggressive mutation and probably related to the Hashimoto’s. Bannon then underwent a full thyroid removal, lymph-node surgery, and radioactive iodine to kill the remaining cancer cells, with ongoing scans to monitor whether it’s still in her neck. She believes ChatGPT intervened just in time to prevent the disease from spreading unchecked. “Without it, the cancer would have spread,” she said. If she had simply taken the rheumatoid arthritis medication and stopped searching, “God knows where it would have gone,” she said. ChatGPT empowered Lauren to advocate for herself, ask for the tests she needed, and keep fighting until the healthcare system responded. “It really saved my life.”

Introducing GPT‑5.4—our most capable and efficient frontier model for professional work. GPT‑5.4 brings together the best of our recent advances in reasoning, coding, and agentic workflows into a single frontier model. It's our most factual and efficient model: fewer tokens, faster speed. GPT-5.4 Thinking and GPT-5.4 Pro are rolling out now in ChatGPT. GPT-5.4 is also now available in the API and Codex. https://lnkd.in/gWvcSwZV

GPT-5.3 Instant in ChatGPT is now rolling out to everyone. More accurate, less cringe, and better web search. https://lnkd.in/epW9visG

We’re partnering with Amazon to accelerate AI innovation for enterprises, startups, and end consumers around the world. https://lnkd.in/g7y85Y-9

AI demand is growing rapidly as more people and businesses use AI to learn, build, and get work done every day. Today we’re announcing $110B in new investment, with support from SoftBank Group Corp., NVIDIA, and Amazon, to help scale the infrastructure needed to meet that demand and make AI more accessible, reliable, and useful for everyone. Hundreds of millions of people are using ChatGPT each week, and as usage grows, continued investment in compute, distribution, and partnerships is essential to bringing frontier AI to more communities worldwide. https://lnkd.in/gZ65Cjrh

We’re partnering with the Council of Fashion Designers of America (CFDA) to launch The Innovation Hub, a new two-year initiative designed to help American designers and brands explore the creative and business potential of AI. The program will pair promising CFDA members with leading AI builders to co-create tools that address real-world challenges facing fashion today in ways that are practical, responsible, and scalable. Our goal is to show how emerging technologies can meaningfully support creativity, strengthen business longevity, and drive positive change across the industry, while keeping designers firmly in the driver’s seat. https://lnkd.in/eZkxWB4e

🦞OpenClaw creator Peter Steinberger shares his best advice for developers today. On Builders Unscripted Ep. 1, he unpacks the journey of building OpenClaw, the power of open source, and how he uses Codex. See the full episode: https://lnkd.in/gkh_MEvJ

Stargate is the umbrella brand for our compute strategy. It’s about mobilizing the full ecosystem to deliver a step-change in global AI compute — and over the past few quarters that vision has become reality. Since announcing Stargate in January 2025, OpenAI has expanded from a mostly single-provider model to a broad partner network across clouds, silicon, and infrastructure: SoftBank, NVIDIA, AMD, Broadcom, Oracle, Microsoft, AWS, CoreWeave, and Cerebras. Demand is compounding, and no single provider, chip, or cloud can carry the load. A diversified compute model is the only way to scale at the pace AI requires. We exited 2025 with ~2 GW of available compute and a model designed to scale: long-term capacity agreements, purpose-built colo deployments, and deep collaboration on next-generation datacenter design. Compute leadership is the foundation of research and product velocity — and Stargate is how we build what comes next.