SandboxAQ

@SandboxAQ

Leveraging AQ - the powerful compound effects of AI + Quantum technology

Palo Alto, CA

sandboxaq.com

Joined March 2022

Pinned
SandboxAQ
@SandboxAQ
Jun 17
A major milestone for American semiconductor manufacturing. Today, SandboxAQ announced a definitive agreement with the U.S. Department of Commerce for a $500 million CHIPS award to help tackle one of the most urgent challenges in American manufacturing: securing the critical
SandboxAQ
@SandboxAQ
Aug 12
Ternary complexes are central to targeted protein degradation, and they are notoriously hard to predict. The relevant biology depends on more than a ligand binding a single protein; it depends on how the ligand, target protein, and E3 ligase come together in three-dimensional
SandboxAQ
@SandboxAQ
Aug 10
Binding affinity matters, but for GPCR drug discovery it only tells part of the story. A compound can bind to a receptor and still produce very different functional outcomes depending on which receptor state it stabilizes. In this work, we combine machine-learning affinity
SandboxAQ
@SandboxAQ
Aug 8
SandboxAQ Essential Concepts – Quantum Computers What if there wasn't just one way to build a quantum computer? Unlike classical computers, which rely on a standardized architecture, quantum computers can be built using several fundamentally different types of qubits. Each
SandboxAQ
@SandboxAQ
Aug 7
Finding a promising target is not just a structure-prediction problem. It is a context problem. This work integrates AI-based protein-structure prediction, proteochemometric modeling, knowledge graphs, and physics-based binding-affinity calculations into an in-silico