One of our most popular preprints of 2025 is now published in @ScienceMagazine. Congrats to @BrianHie, @samuelhking, and team on establishing a framework for generating and evaluating AI-generated genomes.
- Access the paper: science.org/doi/10.1126/sc…
In a new preprint from @BrianHie’s lab, the team reports the first generative design of viable bacteriophage genomes.
Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.

