We're adding 10 years to healthy human lifespan

Retro team sitting on shipping container.
How we work
01
Replace

Some cells are easier to replace than to fix. We clear out old or diseased microglia and blood stem cells and put in young ones, grown from reprogrammed stem cells (iPSCs) in our own GMP facility.

02
Rejuvenate

Most cells can’t be swapped, so we treat them where they are, with small molecules, gene therapy, and AI-designed proteins aimed at the hallmarks of cellular aging. Our furthest along, a drug designed to improve cellular recycling (autophagy), is in a Phase 1 trial.

03
Make the data

AI is crushing fields rich in data. Biology’s data is scarce and siloed, so we generate our own on robots run by PyLabRobot, our open-source lab software. With OpenAI, we built a protein model that redesigned two Yamanaka factors. In cells, the new versions drove over 50x more stem cell marker expression than the originals.

Built for speed

Most biotechs outsource the slow steps and wait on vendors. We built them in-house: cell manufacturing, a vivarium, lab automation, our own software. So we run an experiment, read the result, and start the next one without waiting on anyone.

Our Science

What we’re working on.

Explore our science
Life at Retro Biosciences
Life at Retro Biosciences
Life at Retro Biosciences
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Life at Retro Biosciences