An integrated system to detect and respond to a life-threatening allergic reaction. Monitors three indicators of anaphylactic shock:

• Histamine levels in the blood
• Blood pressure
• Core body temperature

Histamine: Normal histamine levels in a non-allergic person are around 0.9 nmol/L. Histamine levels of 6.35 nmol/L or higher are indicative of a life-threatening allergic reaction. Blood pressure: A blood pressure drop of 30% or more from a person's baseline due to vasodilation can indicate an allergic reaction. Core body temperature: Core body temperature drops during an allergic reaction, by between 5.6 and 6.8 degrees celsius.