At USC, Innovation Isn’t Just a Word – It’s Our DNA.

USC Trojan entrepreneurs are fueling the future, one breakthrough at a time.

Who We Are

USC’s Innovation Ecosystem connects and empowers Trojan entrepreneurs, transforming groundbreaking research into real-world solutions.

Facilitated by the Office of Research and Innovation, we provide comprehensive support at every stage of the entrepreneurial journey, driving impact and advancing society.

By The Numbers

#11

USC’s rank in Inc. Magazine’s and Fast Company’s Ignition Schools list of Top 50 academic institutions for entrepreneurship and innovation

#4

Los Angeles’s rank in the 2024 Global Startup Ecosystem Report of the world’s leading startup ecosystems

#15

USC’s ranking of PitchBook’s Universities Top 100 global colleges ranked by startup founders

What We Do

Empowering Innovation at Every Stage

Inspire

Spark your entrepreneurial journey—USC’s early-stage programs ignite ideas, fuel innovation, and turn ambition into action!

Ignite

From spark to startup—Office of Research and Innovation’s seed funding and internal support programs help early-stage ventures gain traction and thrive.

Invest

Big ideas deserve bold backing—USC strategically invests in its entrepreneurs to accelerate startup success.

Innovation Allies: Our Team

USC’s innovation ecosystem is powered by internal and external partners dedicated to Trojan entrepreneurs. Meet the allies who help turn groundbreaking ideas into real-world impact.

Innovation Core

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Office of Research Initiatives and Infrastructure

Learn more at rii.usc.edu

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Office of Research Strategy and Development

Learn more at rsd.usc.edu

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USC Stevens Center for Innovation

Learn more at stevens.usc.edu

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USC Alfred E. Mann Institute

Email us at twarsi@usc.edu

Foundational Partner

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Digital Economy Program

USC + Techstars Partnership

Campus Partners

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Innovation Quest

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USC Marshall School of Business

Lloyd Greif Center for Entrepreneurial Studies

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USC Viterbi School of Engineering

Technology Innovation & Entrepreneurship

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USC Viterbi School of Engineering

I-Corps Hub:
West Region

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Keck School of Medicine of USC

MESH Strategic Partnerships

News & Events: The Pulse of Innovation

Latest News

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  • USC OORI-Organized Venture & Innovation Summit Showcases a Thriving Innovation Ecosystem
    by Jordan Locy on April 28, 2026 at 5:41 pm

    Author – Ethan Bochicchio The USC Venture & Innovation Summit, held on February 12, underscored the growing strength of Southern California’s innovation economy and the University of Southern California’s central role in it. Hosted by USC’s Office of Research and Innovation (OORI) and sponsored by Amgen and J.P. Morgan, the daylong event brought together faculty, founders, investors, corporate leaders,…

  • From Lab to Launch: OORI Support Drives SBIR/STTR Success for USC Startup AO Tech
    by Jordan Locy on April 27, 2026 at 10:24 pm

    Author – Ethan Bochicchio AO Tech, a startup born out of the University of Southern California’s (USC) research ecosystem, has achieved a major milestone by securing both a National Institutes of Health (NIH) STTR Phase I award of approximately $300,000 and an ARPA-H STTR Fast-Track Phase I/II award totaling roughly $3.7 million, about $1.5 million of…

  • OORI Unlocks Microsoft for Startups Resources for USC Entrepreneurs
    by Jordan Locy on March 27, 2026 at 9:42 pm

    Author – Ethan Bochicchio Through its expanding network of external collaborators, the Office of Research and Innovation (OORI) has enabled USC founders to access Microsoft for Startups resources by joining the Microsoft for Startups Investor Network. This engagement offers benefits to Trojan entrepreneurs, including cloud credits, go-to-market support, and AI tools. By building these partnerships,…

  • AMI Makes Exciting Investment in Innata Bio
    by Jordan Locy on March 26, 2026 at 7:42 pm

    By – Ethan Bochicchio & Jordan Locy Innata Bio is an inflammation-modulation platform company at the clinical stage, focused on developing advanced treatments to address aging-related inflammation. Co-founded by USCS’s Dr. Denis Evseenko, Innata Bio has identified a key link between inflammation and cellular aging and has created a patented platform to reverse this process.…

  • USC/OORI Funded App Corresi Shows Promising Success
    by Jordan Locy on March 26, 2026 at 4:22 pm

    Author – Ethan Bochicchio At the University of Southern California (USC), the Office of Research and Innovation (OORI) is turning early-stage ideas into real-world impact, as demonstrated by the success of Corresi. Starting in 2024 through the OORI-funded Innovation Empowerment Initiative, a part of OORI’s Innovation Catalyst Program, Corresi quickly developed into a launched app…

Upcoming Events

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Success Stories: Trojan Entrepreneurs in Motion