As an independent research institute, TPIRC stays focused on one goal: Improving patient outcomes through science and data.
Infant & Lung Development
Advancing early lung and neurodevelopment in infants with BPD through early risk identification, data-driven care, and research.
Rare Lung Diseases
Improving outcomes for rare and complex lung diseases through personalized diagnostics, real-world data, and targeted research.
Exercise & Lung Longevity
Studying lung performance under physical stress to optimize lung capacity, recovery, and long-term respiratory health.
Food Molecules & Gut Health
Exploring how food molecules affect the gut and immune system to advance personalized treatments for food allergies and related conditions.
Immune System Health
Advancing understanding of immune system disorders to improve diagnosis, treatment, and patient outcomes.
At TPIRC, every part of our work is connected. Diagnostics provide detailed patient insights, which feed into Data Science & AI to uncover patterns that guide Clinical Care. Research builds on these outcomes to drive Discovery, creating new tools and treatments. Unlike traditional models, these discoveries loop back to improve diagnostics, care, and data, continuously enhancing patient outcomes.
At TPIRC, every part of our work is connected. Diagnostics provide detailed patient insights, which feed into Data Science & AI to uncover patterns that guide Clinical Care. Research builds on these outcomes to drive Discovery, creating new tools and treatments. Unlike traditional models, these discoveries loop back to improve diagnostics, care, and data, continuously enhancing patient outcomes.
We translate research into real-world clinical action through Lung & Allergy Health Associates (LAHA), ensuring scientific insights directly improve diagnosis, treatment, and outcomes.
Applying tools like Impulse Oscillometry (IOS) and Exercise CPET to assess lung health earlier and more precisely.
Secondary Immune Deficiency and Reproductive Immunology.
Delivering evidence-based care backed by Joint Commission Disease-Specific Certification in Pediatric Asthma.
Our discovery science investigates the biological mechanisms that drive lung, immune, and food-related disease, generating the evidence that fuels innovation across TPIRC.
Studying immune signaling, inflammation, and tissue development to understand disease at its root.
Advancing parallel investigations across lung biology and immune-mediated responses to accelerate insight.
Leveraging patient-derived samples to identify biomarkers and mechanisms linked to long-term health outcomes.
We use advanced mathematics and artificial intelligence to connect data across diagnostics, care, and research, enabling prediction, precision, and safer personalization.
Applying AI/ML to model biological systems and disease progression.
Developing mathematical methods that move beyond population averages toward individualized care.
Supporting responsible innovation through data-driven insights that enhance patient safety and clinical decision-making.
Foundational research uncovering the mechanisms that drive lung, immune, and food-related disease.

Investigating lung development, inflammation, and injury at the molecular and cellular level.
Studying immune responses in developing lungs during non-invasive ventilation.
Evaluating CPAP’s role in reducing lung injury in premature
infants.
Quantifying neutrophil infiltration and inflammatory pathways driving disease progression.

Understanding how immune and food protein interactions influence tolerance, allergy, and disease outcomes.
Examining antibody class switching and B cell behavior using Biobank samples.
Characterizing allergenic proteins in almond and walnut to understand prevalence and risk.
Studying how anxiety and behavioral factors affect treatment response.
Patient participation enables the discovery of biomarkers and mechanisms linked to long-term immune tolerance and disease outcomes.
Through our integrated research infrastructure, each contribution becomes part of a dynamic data ecosystem that connects clinical outcomes with underlying immune patterns. This approach allows our team to translate individual patient data into broader insights that inform precision therapies, disease modeling, and future standards of care across immune-mediated conditions.
On behalf of Ezra and our whole family, we want to say thank you very much for the generous gift, enabling Ezra to continue the program without pause and for supporting our family in this way. Not only does it help Ezra, but the program in its entirety, furthers the future of food allergies, and makes a difference in so many families’ lives. We thank you for caring for the program, and for those in the program.
Thank you to the generous donors of TPIRC. Because of you, our family was able to afford our son’s remission visit.
After Hudson’s mother suffered a stroke and life-saving brain surgery, our family faced significant financial hardship. Your kindness provided $1,000 toward Hudson’s care and made his visit possible.
We are deeply grateful to TPIRC, its donors, and the Food Allergy Institute for giving our family hope.
Living with cystic fibrosis, I had seen many doctors, but nothing really worked for me. Dr. Randhawa listened, created a treatment plan just for me, and my lung function improved from 40 to 60, the highest it’s ever been.
He didn’t just follow the usual protocols; he truly understood me. The improvements I’ve seen aren’t just numbers; they’ve given me real freedom in my daily life. Personalized care like this can change everything.
After years of chronic sinus infections and a late cystic fibrosis diagnosis, I found TPIRC and Dr. Randhawa. Their personalized approach finally addressed my real needs and helped me see a future beyond my condition.
Today, I’m thriving as a doctoral student and living proof of what individualized care can make possible.
My life always seemed ordinary except for constant sinus infections. At 18, just before college, I was finally diagnosed with Cystic Fibrosis. My early treatment was generic, but Dr. Randhawa created a plan just for me, addressing my unique needs and sinus issues. Over time, I stopped seeing myself only as a CF patient. Today, I am a doctoral student in Clinical Psychology, living a life not defined by my condition.
We are deeply grateful for your generous donation, which made it possible for Ellie to participate in this life-changing program. Your kindness lifted a significant financial burden from our family and allowed us to focus fully on supporting our daughter through her treatment.
Thank you for investing in Ellie’s health and future. Your support means more to our family than words can express.
At TPIRC, transformative care starts with a simple act of giving. Your support helps us deliver cutting-edge solutions to families who have nowhere else to turn.