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Excited to share our latest work published today in @NatImmunol! π Together with Taja Vatovec, we investigated how somatic CBL deficiency affects B cell development and function.
Anna-Lena Neehus
154 posts
Anna-Lena Neehus
@ALNeehus
Postdoc @bloodgenes @bostonchildrens πΊπΈ | PhD @casanova_lab @institutimagine π«π· | Immunologist studying human genetics |
Boston, MA
Joined November 2019
- 1/ Exactly one year after my PhD defense, I am very excited to share with you the last chapter of my thesis published today in @Nature about humans with inherited TNF deficiency: nature.com/articles/s4158β¦.
- I am beyond excited to share the main project of my PhD @casanova_lab which is now out @CellCellPress (doi.org/10.1016/j.cellβ¦). We describe how human CCR2 deficiency leads to impaired monocyte recruitment to the lung, resulting in pulmonary alveolar proteinosis.
00:001/ We are excited to report the discovery and mechanistic exploration of human AR complete CCR2 deficiency in @CellCellPress. Surprisingly, CCR2 deficiency underlies two narrow phenotypes: progressive polycystic lung disease and mycobacterial disease (sciencedirect.com/science/articlβ¦). - Happy to share my first PhD paper investigating the mechanism by which human PKCD deficiency underlies susceptibility to infectious disease. Published today in @JExpMed bit.ly/36K8QKV @casanova_lab
- We wrote a review! π Digging into autoimmunity against immunity, which is often (but not only π) results in susceptibility to infectious diseases!1/ We are happy to share our review on βThe Ouroboros of Autoimmunityβ published in @NatImmunol! (nature.com/articles/s4159β¦)
- Happy to share that I received the @EMBO Postdoctoral Fellowship @EMBOFellows to continue my work with @bloodgenes to decipher mechanisms underlying B cell leukemia and B cell deficiencies! π₯³
- Ever wondered how to differentiate monocytes towards alveolar macrophage-like cells? Together with @SusantaPahari4 we wrote up a detailed protocol to guide you through all critical steps: star-protocols.cell.com/protocols/3461
- Happy to share our latest report on a new clinical manifestation in p40phox deficiency! There is still so much to learn! Great work together with @casanova_lab @BustamanteJaci1 @LevyRomain and others who are not yet on twitter.
- Today we report a new #PKCD-deficient patient, highlighting that PKCD deficiency can phenocopy chronic granulomatous disease. link.springer.com/article/10.100β¦ Thanks to all people involved in this study @anne_puel @casanova_lab, @BustamanteJaci1 and those not yet on Twitter π«π·πΊπΈ
- What a great meeting in St. Louis with so many amazing scientists and friends! @DanyelLee123 @ryangrui @ZhiyongLiu7 @PhilippotQ Tom and Adrian! #CIS2023 @ClinImmSoc
- Very proud to see our recent work on CCR2 deficiency featured in The Scientist today! π©βπ¬π¬ @casanova_lab tinyurl.com/bddk9ajt
- Leaving this years #ESID2024 meeting where i had the chance to present my previous and current work and got to meet many fantastic scientist and friends! Thank you @ESIDsociety for this exciting meeting full of inspiration and I am looking forward to the next one!
- Very happy to have contributed some functional validation for this study on the evolution of host defense over the last 10 millennia! @GaspardKerner @QuintanaMurci
