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Alejo Rodriguez-Fraticelli
@AlejoFraticelli
Quantitative analysis of aging/cancer heterogeneity - @fraticellilab @icreacommunity @IRBbarcelona @ERC_research @criscancer @CaixaResearch 🇦🇷🇪🇺🇺🇸
Barcelona, España
fraticellilab.com
Joined November 2018
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Feb 26
    🚨 NEW @FraticelliLab PREPRINT JUST WENT LIVE biorxiv.org/content/10.648… Here, we describe PLSTCs, Soluplus-based expansion cultures of primary mouse *Acute Myeloid Leukemia* Stem Cells. And then we use LARRY barcoding to identify drivers of leukemogenicity and drug resistance!
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Feb 5, 2020
    I would actually love a “1000 biology papers you need to read before you die” book. About 1000 pages long: each page focused on 1 paper, with its original abstract or summary, a brief “review” of why its important, and 2-3 suggested further readings. Would anyone buy this?
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Oct 31, 2024
    Ready for halloween!!!! I’m your worst nightmare!!!!
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Dec 27, 2020
    It is very dangerous to label the development of these #COVIDー19 vaccines as “a miracle” or “in record time”. Over 40 years of research in mRNA biotech and billions of dollars invested through sustained private and public funding have been required to make this happen. 1/
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Oct 7, 2024
    Nobel prizes are a constant reminder of the things you thought had already won the Nobel Prize.
    42K
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Dec 6, 2020
    Wow. 8 years ago we had the CRISPR paper by @doudna_lab ... Today, >10 patients essentially cured of Sickle cell disease and Beta-Thalassemia... @CRISPRTX @VertexPharma ... I don’t know if I’m quite realizing the kind of historic moment I’m living. #ASH2020
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Jul 15, 2020
    Yayy!!!! Our newest article, just out @nature!!! Here, we combined single cell lineage tracing and serial transplantation to unveil the genetic programme that defines the sought-after LT-HSC property!!! nature.com/articles/s4158…
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Nov 25, 2020
    Alright everyone, the cat is out of the bag! I'm excited to announce that my independent group, Quantitative Stem Cell Dynamics (fraticellilab.com), will finally be opening its doors in 2021 at @IRBBarcelona!!!! We're planning to recruit at multiple levels!!! 🩸🔬🦀💻📶
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Jun 1, 2024
    2021 rejection: “it will never work” 2022 rejection: “it will never work” 2023 rejection: “it will never work” 2024 rejection: “this has already been shown” 😂
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    Natural killer cells show their cancer-fighting worth
    From nature.com
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Jan 10, 2022
    So extremely happy to announce that our lab @FraticelliLab has been awarded an @ERC_Research Starting Grant to work on HSC memory!! 🎉🎉🎉🎉 Congrats to the other awardees, including our @IRBBarcelona partners, @CrisMayorRuiz lab!!! 🔬🥽🧪 #FrontierResearch #EUfunded
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    European Research Council (ERC)
    @ERC_Research
    Jan 10, 2022
    🎉ERC Starting Grant competition results are out! Over €619 million for the best ideas of young leading researchers - and the 1️⃣st set of grants awarded under 🇪🇺@HorizonEU. Find out who, where and why 👉 bit.ly/3JRyDDg #EUfunded #FrontierResearch #ERCStG
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Jun 25, 2021
    Today is the first day of the most important member of the new lab !!!
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Aug 7, 2022
    I’m not saying I’m a good peer-reviewer. All I’m saying is I don’t go around pretending I know way more than a group of people who dedicated 3-5+ years of their lives to something. No, my job is just try to make sure their major claims are solid and can stand the test of time. 🧐
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Feb 11, 2023
    A single cell state (gene expression, chromatin landscape) is not “the phenotype” of a cell. It’s only a small, small part of the phenotype (incl. disease). We need to move from cell state to cell function (and not just functional prediction).
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    Alejo Rodriguez-Fraticelli
    @AlejoFraticelli
    Sep 7, 2023
    Wow. They’ve actually designed the perfect drug. #semaglutide #ozempic
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