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Brad Spellberg
@BradSpellberg
CMO Los Angeles General Medical Center, hospitalist, infectious diseases expert, researcher
bradspellberg.com
Joined March 2016
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    Brad Spellberg
    @BradSpellberg
    Jun 13
    Thanks to @highlycritical1 for finding new Shorter Is Better RCT for CAP! This is the 15th RCT showing 3-5 d = 7-14 days. And thanks to @Zaydovudine for finding 1996 RCT of amox 6 d vs. PCN V 14 d for GAS pharyngitis! Both added to the tables and website. bradspellberg.com/shorter-is-bet…
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    Brad Spellberg
    @BradSpellberg
    Aug 29, 2021
    Are we over-reading Israel's experience? Iceland & Denmark haven't had severe COVID return. And in LA, 8 months into vaccination, at the 2 public hospitals I'm currently CMO at, 693+ tests since July: 90% of all tests in unvaccinated 98% all admissions due to COVID unvaccinated
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    Brad Spellberg
    @BradSpellberg
    Aug 27, 2022
    Replying to @Dave99117584 and @joaquinlife
    ERs are indeed very busy and hospitals are full because beds are closed because we can’t find enough nurses. But we are not busy with Covid. We are busy with patients who don’t have Covid, many of whom have had care deferred for > 2 years.
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    Brad Spellberg
    @BradSpellberg
    Aug 8, 2021
    Having chart reviewed all COVID+ at 2 public hospitals in LA since early July: 90% of pts with +test not vaccinated 96.4% of pts with +test admitted to hospital for any reason not vaccinated 98.2% of pts with +test admitted to hospital d/t COVID not vaccinated. That is all.
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    Brad Spellberg
    @BradSpellberg
    Jan 2, 2023
    Replying to @johnnyasheville and @StribGuy
    People have been predicting the end of the world for as long as people have had written language. How about we all try to take a deep breath and make 2023 >/=10-fold less unnecessarily dramatic as 2022?
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    Brad Spellberg
    @BradSpellberg
    May 25, 2025
    I recently evaluated a pt with a fever of 40.5 C, WBC 15,000, & hypotensive/tachycardic. I was really torn. Could the pt have inflammation of some kind? I wasn't sure. But then, thankfully, I saw that someone had ordered a CRP. And that's when I knew there was inflammation.
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    Brad Spellberg
    @BradSpellberg
    Jul 12, 2020
    Finally got around to updating Shorter Is Better Table, now with 10th CAP trial (pediatrics) included. Updated 7/12/20:
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    Brad Spellberg
    @BradSpellberg
    May 6, 2022
    Confession: I haven't been on a plane in >2 years, and Im reluctant. But invited to give a talk on oral Abx at ID Week. I was hoping it would be virtual, but apparently not. I guess I have some COVID PTSD. Should I do it? Are people comfortable traveling at this point?
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    Brad Spellberg
    @BradSpellberg
    Jan 1, 2022
    Replying to @eliowa
    I can tell you that at the two public hospitals in LA for which i review all Covid + tests, at this point only 1/3 of Covid+ admissions are admitted because of Covid. And only 20-25% +tests in ED are admitted. Agree, reliance upon administrative data is misleading.
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    Brad Spellberg
    @BradSpellberg
    Sep 9, 2020
    Replying to @jakescottMD
    Used to see lots of that. But rifabutin is now a promising option for such cases. And colistin is still there. And there’s eravacycline and cefedericol.
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    Brad Spellberg
    @BradSpellberg
    Nov 28, 2020
    Alright ID Tweeps, Shorter Is Better table is now updated with new DFO study. Table is getting awfully full! bradspellberg.com/shorter-is-bet…
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    Brad Spellberg
    @BradSpellberg
    Sep 4, 2022
    General observation. It's really hard to be in the middle. You take flak from both extremes. Which is why it's all the more important that we try to move towards the middle. Decreasing polarization is good, don't you think?
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    Brad Spellberg
    @BradSpellberg
    Jan 23, 2020
    Note to the world. I’m sick to death of admitting young women to the hospital with advanced stage cervical cancer. It’s tragic and totally preventable. Vaccines save lives. Deniers kill.
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    Brad Spellberg
    @BradSpellberg
    Mar 26, 2021
    Update Shorter Is Better Table! 12 CAP studies now! 3 days taking over from 5? bradspellberg.com/shorter-is-bet…
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