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FrezzaLab
@FrezzaLab
We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. network.febs.org/users/399680-c…
Koln, Germany
frezza.cecad-labs.uni-koeln.de/home
Joined December 2017
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    FrezzaLab
    @FrezzaLab
    Aug 9, 2021
    This is a topic I am very passionate about, and something I am learning every day. I hope you will enjoy the read, and you will find it useful. Happy to hear your views about the topic. The mindful scientist network.febs.org/posts/the-mind… #FEBSnet
    network.febs.org
    The mindful scientist
    A more mindful approach to science can help scientists to handle negative and positive emotions better.
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    FrezzaLab
    @FrezzaLab
    Sep 1, 2021
    I am thrilled to announce that the Frezzalab will join the @CECAD_ @UniCologneNY as @AvHStiftung professor in October. I am sad to leave Cambridge and the wonderful colleagues I met here, but also incredibly excited to start this new adventure in Cologne. bit.ly/3ywgggp
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    FrezzaLab
    @FrezzaLab
    Mar 8, 2023
    Happy to share the results of our collab with @LabPrudent, led by @vincentZecchin1 and Vincent Paupe @Nature ! We show that Fumarate drives mtDNA release in the cytosol via mitochondrial-derived vesicles (MDVs) to trigger innate immunity!
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    Fumarate induces vesicular release of mtDNA to drive innate immunity
    From nature.com
    74K
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    FrezzaLab
    @FrezzaLab
    Nov 17, 2020
    I am honoured to have been awarded the #AvHProfessorship. This is testament of the great work of the lab members over the past years. A huge "thank you" to @CECAD_ for sponsoring and supporting me on this endeavour.
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    CECAD Cologne
    @CECAD_
    Nov 17, 2020
    🎉Congratulations to Christian Frezza @FrezzaLab to be awarded a #AvHProfessor. Appointment negotiations are ongoing and we hope to see him soon at our #AgingResearch campus @CECAD_ @UniCologne
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    FrezzaLab
    @FrezzaLab
    Aug 20, 2023
    Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
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    Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
    From nature.com
    57K
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    FrezzaLab
    @FrezzaLab
    Sep 28, 2021
    Here it is. @Alestang01 and I are flying to Cologne. It is not easy to move, especially during a pandemic, Brexit, and a fuel shortage.. And moving the lab. But we are getting there. See you on the other side!
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    FrezzaLab
    @FrezzaLab
    Nov 6, 2024
    "Cellular ATP demand creates metabolically distinct subpopulations of mitochondria"
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    Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
    From nature.com
    24K
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    FrezzaLab
    @FrezzaLab
    Apr 17, 2022
    Mitochondrial shape alteration by metabolites | Nature Cell Biology nature.com/articles/s4155…
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    FrezzaLab
    @FrezzaLab
    Aug 7, 2022
    Nucleotide imbalance decouples cell growth from cell proliferation | Nature Cell Biology
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    Nucleotide imbalance decouples cell growth from cell proliferation
    From nature.com
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    FrezzaLab
    @FrezzaLab
    Jul 8, 2020
    We have discussed many times what it means to leave your own country for a job in science. Here are my thoughts, inspired as always by many friends, including @alesposito75 @Pluchinolab @Alestang01 and all my lab members Leaving home for science network.febs.org/posts/leaving-… #FEBSnet
    network.febs.org
    Leaving home for science
    On the many things nobody told me when I decided to move abroad for a postdoc.
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    FrezzaLab
    @FrezzaLab
    Jul 29, 2021
    We are very proud to present our latest work and first preprint, a tour de force driven by Dylan Ryan. A short 🧵 below. Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
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    biorxiv.org
    Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
    The Tricarboxylic Acid Cycle (TCA) cycle is arguably the most critical metabolic cycle in physiology and exists as an essential interface coordinating cellular metabolism, bioenergetics, and redox...
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    FrezzaLab
    @FrezzaLab
    May 19, 2020
    I am sure most of you have thought of (and was asked) this question. Here my views about how to tackle it. This is a very personal take, so feel free to comment and disagree Thanks to @FEBSnews "So, do you want to be a PI?" network.febs.org/channels/723-e… #FEBSnet
    network.febs.org
    So, do you want to be a PI?
    During a postdoc many of you will be asked whether you want to become a Principal Investigator (PI) – an academic position of financial and intellectual independence, with direct responsibility for...
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    FrezzaLab
    @FrezzaLab
    Feb 20, 2021
    In academia, you often hear "I love my job" as self-justification for enduring despite instability, long working hours, and low-paid job, to the great advantage of the employer. Why can't it be considered a normal job? This narrative has to change.
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    FrezzaLab
    @FrezzaLab
    Oct 16, 2022
    This is an interesting protocol for rapid fractionation of mitochondria from @Mito_Redox with some help from us @ASofiaHCosta Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation
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    FEBS Press
    From febs.onlinelibrary.wiley.com