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John Maraganore 🇺🇸🇬🇷🇺🇦
4,351 posts
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John Maraganore 🇺🇸🇬🇷🇺🇦
@JMaraganore
Founding CEO of @Alnylam. Pioneered RNAi therapeutics as a whole new class of medicines for patients. Now bioentrepreneur-at-large. Opinions are my own.
Boston, MA
alnylam.com
Joined June 2017
423
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16.3K
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  • user avatar
    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Dec 17, 2021
    And so, my friends, it’s a wrap! Leaving Alnylam as CEO for the last time. The last 19+ years have been epic. Thanks to all my colleagues and supporters!
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Aug 3, 2024
    In Jan 2021, we launched our “Alnylam P5x25” strategy for building a top 5 biotech by end of 2025… On Friday, we achieved that milestone! AMGN > VRTX > REGN > GILD > ALNY Congrats to the amazing @Alnylam team!
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    48K
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    May 21, 2022
    OMG, how does this happen!? DNA makes RNA makes specific protein structures based on codon usage nature.com/articles/s4146…
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Jan 7, 2024
    Student interested in biotech via non-PhD/MD route reached out to me last year… he just got into Stanford undergrad. Here was my advice to him. 🧵1
    154K
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    May 9, 2022
    Read my Reflections on @Alnylam (and the importance of being unreasonable), published with @SpringerNature in ⁦@NatureBiotech⁩. Many lessons over last 20 yrs.
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    Reflections on Alnylam
    From nature.com
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Jun 14, 2020
    Happy B-Day @Alnylam!!! 18 years, 2 approved medicines, 2 more in registration, 11 more in Clin development, a WHOLE NEW CLASS OF MEDICINES!!! And, we’re still a teen!
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Mar 7, 2022
    Got my first RNAi therapeutics dose today! So #alnylamproud!
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Oct 8, 2024
    Very excited to launch City Therapeutics this am!!!! “I’m a big believer in where Alnylam is going, but RNAi is even bigger than that, and there’s a need for new pioneers in the space. City Therapeutics is my next-generation RNAi play.”
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    Biotech veteran John Maraganore raises $135 million for his ‘next-generation RNAi’ startup
    From statnews.com
    14K
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Aug 10, 2018
    With today’s @US_FDA approval of ONPATTRO, the 1st FDA-approved #RNAi tx, we mark the arrival of an exciting new class of medicines that has been >15 years in the making! More important is the new hope this will bring to a #raredisease community so greatly in need of treatments.
    user avatar
    Alnylam Pharmaceuticals
    @Alnylam
    Aug 10, 2018
    We are thrilled to share the news that we have received @US_FDA approval for ONPATTRO (patisiran), our first commercial product and the first-ever #RNAi therapeutic.
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Dec 1, 2021
    Thrilled to be joining ARCH as a Venture Partner as part of my plan to work with leading VCs! Looking forward to working w/ the team & the next generation of biotechs to advance promising science that can improve patients' lives.
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    ARCH Venture Partners Announces Several Key Appointments
    From prnewswire.com
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Oct 29, 2021
    After a week where we announced our CEO transition, going home for the weekend feeling SO proud of what we’ve accomplished (so far) with #RNAi Rx for patients! More coming!!!
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Sep 20, 2017
    Proud day! Validation of 15 years of scientific endeavor! 1st ever positive Ph3 results for #RNAi therapeutic. bit.ly/2hhuUm5
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Feb 6, 2025
    Same story, 14 years and one day later. For the sake of patients, let’s hope for the same outcome! Keep going, CRISPR folk!
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    50K
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    John Maraganore 🇺🇸🇬🇷🇺🇦
    @JMaraganore
    Mar 21, 2019
    My father died a little over a year ago with Alzheimer’s, a disease that robbed him off his life’s memories. This is a very sad day!!! To my friends at @biogen, thanks for trying and don’t give up! endpts.com/biogens-alzhei…
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