A long journey started almost 40 years ago🤪😁in France
Jean-Frederic Colombel
1,219 posts
Jean-Frederic Colombel
@JeanFredericCo1
Director Inflammatory Bowel Disease Center Icahn School of Medicine at Mount Sinai New York
Joined September 2019
- Well…This is the end of my 40th DDW🤪First one in NYC in 1982 Still so much fun and great to reconnect with friends!!
- To all my friends I asked these questions 10 years ago and still have no answer to ONE!!! Waiting for your input 😁
- Landmark trial 😁👍 Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial - The Lancet Gastroenterology & Hepatology
- Early is key in CD. Next frontier is to catch the disease before diagnosis! Early Biologic Treatment Decreases Risk of Surgery in Crohn's Disease but not in Ulcerative Colitis: Systematic Rev…
- - Took years to recruit bionaive patients ! - Rationale combination needed to be transformative - Bayesian analysis should be used more for POC studies Vedolizumab, Adalimumab, and Methotrexate Combination Therapy in Crohn's Disease (EXPLORER)
- The future target in IBD ! Biopsy and blood-based molecular biomarker of inflammation in IBD.
- Replying to @MondayNightIBD @pedsIBDdoc and 10 othersPrecision medicine is the Loch Ness monster of IBD Everybody talking or writing about it but nobody has seen it !🤪
- Urgent need to understand more about diet and ibd as shown by this “heat map” of “good” and “bad” food according to different recommended diets !!! In a nutshell it is a mess 🤪This is from editorial in Gastroenterology that we wrote with Joao Sabino from Leuven !!!!
- Four NIH K awardees in our GE division in record time ! Youth is blossoming at Sinai.Research in predictors of response of IBD therapy, host microbe interactions, early life risk factors for Ibd and role of wearable device. More coming soon ! @ManasiAgrawalMD @ryanungaro123
- First Ecco lecture by David ! ECCO is global 👍😁😁
- Was thinking that complications of CD mostly occur as a consequence of disease progression from diagnosis. Not only !!!! Preclinical Serological Signatures are Associated with Complicated Crohn's Disease Phenotype at Diagnosis.
- Effectiveness of Upadacitinib for Patients with Acute Severe Ulcerative Colitis: A Multi-Center Experience. pubmed.ncbi.nlm.nih.gov/38275248/
