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Mike “Let’s go Knicks!” Mitchell
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Mike “Let’s go Knicks!” Mitchell
@MJMitchell_Lab
Diehard @nyknicks fan | Professor of Bioengineering | Lipid Nanoparticles | mRNA Therapeutics & Vaccines | Drug Delivery | Biomaterials | Immunotherapy
Madison Square Garden
mitchell-lab.seas.upenn.edu
Joined August 2011
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Mar 19
    Excited to share our latest @NatureNano led by @MJMitchell_Lab Postdoctoral Fellow @ShiQiangqiang on a new class of ionizable lipids that act as prodrugs to create an in situ vaccine within solid tumors that also eradicate distant tumors! Free access: rdcu.be/e8Lq6
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Feb 22, 2023
    Super excited to be awarded tenure @Penn! Huge thanks to lab members, colleagues @pennbioeng, and letter writers for making this possible. It’s been an honor to watch @MJMitchell_Lab open in Summer 2018 and grow to 40+ members. So proud of the team and the best is yet to come!
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Feb 16, 2022
    Rest In Peace to my brilliant, beautiful, fearless Mom. You came from 🇦🇷 to 🇺🇸 to start a new life, swept my Dad off his feet on a blind date, and pushed Marc and I to reach heights we never thought possible. My lab and I will cure this disease in your honor. I love you Mom.
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Sep 1, 2022
    Excited to launch the @Penn Institute for RNA Innovation directed by @WeissmanLab and serve as the Lipid Nanoparticle (LNP) Delivery Systems Group Leader! We look forward partnering w academia + industry to develop transformative RNA delivery tech! Link: rnainnovation.med.upenn.edu
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Feb 2, 2022
    Honored to receive the Young Investigator Award from @SFBiomaterials, my home society that's supported me since I was a student! Huge thanks to @BurdickLab @profmikeking Bob Langer for nominating me + the @MJMitchell_Lab team that make this the dream job! blog.seas.upenn.edu/michael-mitche…
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Apr 26, 2022
    Excited to announce that our lab has received an @NSF CAREER Award! Led by @MJMitchell_Lab PhD student @AlvMukalel, we will create new mRNA lipid nanoparticle tech to engineer macrophages for solid tumor immunotherapy. We are hiring postdocs + PhD students at #SFB2022 this week!
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Oct 2, 2023
    Huge congrats to our friends @WeissmanLab @kkariko for winning the @NobelPrize for the COVID-19 mRNA vaccines! Will never forget the day Drew knocked on my door when I started @pennbioeng in 2018 and asked to collaborate on new LNP technology. Thank you for being a great mentor!
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    The Nobel Prize
    @NobelPrize
    Oct 2, 2023
    BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Jan 29, 2020
    Congrats to my PhD student ⁦@mag_youre_it⁩ on her nano CAR T immunotherapy study ⁦@NanoLetters⁩ making ⁦⁦@Penn⁩’s front page! Maggie was the 1st PhD to join me - not sure why she chose me - but I’ll never forget it #WomenInSTEM #newpi
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    Penn nanoparticles are less toxic to T cells engineered for cancer immunotherapy | Penn Today
    From penntoday.upenn.edu
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Jun 26, 2023
    Thrilled to share our latest in Nature Nanotechnology @NatureNano led by @MJMitchell_Lab Postdoc Fellow @Xuexiang_Han in collaboration with @WeissmanLab on a new class of adjuvant lipidoids that augment the immunogenicity of SARS-CoV-2 mRNA LNP vaccines!
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    Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA...
    From nature.com
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Feb 21, 2024
    Thrilled to share our latest in Nature Biomedical Engineering @natBME led by @MJMitchell_Lab Postdoc Ningqiang Gong on a "switchable" bispecific T cell engager to eliminate solid tumors in a safer manner! Study: nature.com/articles/s4155… @Penn news story: penntoday.upenn.edu/news/switchabl…
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Jan 17, 2023
    Super excited to share our latest in Nature Communications @NatureComms led by @MJMitchell_Lab postdocs @Xuexiang_Han @NingqiangGong on a new ligand tethered LNP platform to unlock RNA delivery to activated fibroblasts to treat liver fibrosis! Paper link: rdcu.be/c3BmL
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Dec 11, 2024
    Excited to share our latest in @Nature led by @SwingleKelsey on new mRNA LNP tech to treat life-threatening pregnancy disorders! Kelsey shows that LNPs engineered to deliver mRNA to the placenta can normalize vascular tissue to ameliorate pre-eclampsia: blog.seas.upenn.edu/a-lipid-nanopa…
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Sep 13, 2023
    Thrilled to share our latest in @NatureMaterials led by @MJMitchell_Lab Postdoc Fellow Ningqiang Gong on creating CAR T cell biomaterial coatings in the body for potent cancer immunotherapy without toxic side effects! Free access: rdcu.be/dlRRz penntoday.upenn.edu/news/suit-armo…
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    Mike “Let’s go Knicks!” Mitchell
    @MJMitchell_Lab
    Sep 22, 2023
    Thrilled to be named a Young Innovator by @CMBEjournal and share our latest work led @MJMitchell_Lab PhD student @CGFigE on a new RNA nanoparticle combination therapy to treat multiple myeloma! Free access to the study: rdcu.be/dmbOx blog.seas.upenn.edu/bioengineering…
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