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Chris J. Maddison
485 posts
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Chris J. Maddison
@cjmaddison
ML faculty @UofT
Toronto, Canada
cs.toronto.edu/~cmaddis/
Joined July 2011
1,934
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19K
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  • user avatar
    Chris J. Maddison
    @cjmaddison
    Jul 24, 2024
    What if the next medical breakthrough is hidden in plain text? Causal estimates drives progress but data is limited & RCTs slow. Introducing NATURAL: a pipeline for causal estimation from text data in hours, not years. Paper: tinyurl.com/ppr29 Site: tinyurl.com/web98
    A figure comparing the type of data used in RCTs vs. our pipeline, NATURAL. It also include a table that shows that in 4 real-world settings, NATURAL estimates came within 3 percentage points of a real-world RCT.
    184K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Aug 4, 2024
    Enough already: T cell inflammation and SARS-CoV-2 virus persist in Long Covid. Editor's choice in @ScienceMagazine Immunology from Friday.
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    science.org
    Enough already: T cell inflammation and SARS-CoV-2 virus persist in Long Covid
    Virus and T cell inflammation persist in the tissues of patients with Long Covid.
    31K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Nov 28, 2024
    Why long COVID may simply be 'long infection' It is very important to make the message simple and optimistic: it seems that some people have long SARS-CoV-2 infections. We now know what we need to do.
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    Stream Your Favourite Local & National Radio Stations - ABC listen
    From abc.net.au
    13K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Apr 5, 2024
    🔥 "Skeptics beat their chests about evidence-based medicine and never grapple with what patients should do when medicine doesn't bother to create an evidence base for your condition." --@edyong209 @SFU 🔥
    9.7K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Jun 30, 2025
    “Finally, maybe this is controversial but ultimately progress in science is bottlenecked by real-world experiments.” If this is controversial in SF, we’re cooked.
    user avatar
    Jason Wei
    @_jasonwei
    Jun 30, 2025
    We don’t have AI self-improves yet, and when we do it will be a game-changer. With more wisdom now compared to the GPT-4 days, it's obvious that it will not be a “fast takeoff”, but rather extremely gradual across many years, probably a decade. The first thing to know is that
    75K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Jan 10, 2025
    Today is the first time I've taught since 2021 and the first time teaching in-person. We'll be studying large language models through a close read of the Llama 3 tech report. I'm grateful to be here, and excited for the term. cs.toronto.edu/~cmaddis/cours…
    13K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Dec 25, 2024
    Merry Christmas, friends and colleagues! I've written a short letter reflecting on our progress. Thank you for everything. cs.toronto.edu/~cmaddis/lette…
    Letter text can be found here: https://www.cs.toronto.edu/~cmaddis/letters/dear_friends_2024.pdf
    13K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Jul 16, 2025
    What makes a great scientist? Most AI scientist benchmarks miss the key skill: designing and analyzing experiments. 🧪 We're introducing SciGym: the first simulated lab environment to benchmark #LLM on experimental design and analysis capabilities. #AI4SCIENCE #ICML25
    Picture of SCIGYM's title and authors
    16K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Dec 21, 2023
    I decided to write out a part of the story of my illness for my #LongCovidMoonshot holiday letter, which I am sending tomorrow to @RepRaulGrijalva, @SenMarkKelly, and @SenatorSinema. 🌼
    A sketch of poppy flowers.
    14K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Jan 2, 2025
    There's a very strong tendency to believe that the medical system has answers for the ailments that you or your loved ones will inevitably develop. Unfortunately, it's not true. The sooner we internalize that, the sooner we fix biotech.
    5.9K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Aug 29, 2025
    The rebuttal process @NeurIPSConf was too collegial and productive, so a bunch of papers whose process ended on a positive note will be rejected.
    33K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Aug 25, 2024
    When I started in Geoff's lab at UofT in 2011, we were handrolling our neural nets in gnumpy (a simple numpy-like wrapper for CUDA written by UofT grad students). If you've ever had to code an LSTM from scratch without autodiff, you know just how cursed this workflow is.
    17K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    May 11, 2025
    My experience as well. The reviewer chaos at NeurIPS / ICLR / ICML degrades their prestige for the people in-the-know, who are arguably the people you want to impress.
    user avatar
    Ahmad Beirami
    @abeirami
    May 11, 2025
    The review quality in TMLR is better because: 1. The authors suggest the AE. This means that the AE is more likely to be the right fit for the paper. 2. The AE selects the best reviewers for the paper who may or may not be in the reviewer pool. ...
    21K
  • user avatar
    Chris J. Maddison
    @cjmaddison
    Nov 12, 2023
    Operation Moonshot (Taylor's Theorem). Zeroth-order goal: let congress know we're here 👋 First-order goal: let congress know we're organizing 💪 Full goal: $1B / year in NIH research funding! 🚀 longcovidmoonshot.com
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    8.8K

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