Pinned
My paper is out!! 🎉
"Opponent control of reinforcement by striatal dopamine and serotonin", @Nature
Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠
THREAD ⬇️
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Daniel Cardozo Pinto
242 posts
Daniel Cardozo Pinto
@dcardozopinto
Neuroscientist & Harvard Junior Fellow | Stanford PhD '23, Malenka lab | UC Berkeley BA '17, Lammel lab
Joined May 2018
- Thrilled to finally share my PhD work, out today as a preprint! 🎉 Q: How do the brain’s dopamine and serotonin systems work together to drive learning? 🧠 Short answer, 🧵 below Long answer: 1/9Striatal integration of inverse dopamine and serotonin signals gates learning biorxiv.org/cgi/content/sh… #bioRxiv
- Out today @NeuroCellPress ! Modulation of serotonin release by dynorphin mediates social deficits during opioid withdrawal Big congrats to first author Matt Pomrenze @mCherryGarcia who has taught me so much about neuropeptides along the way 🎉 LINK -> authors.elsevier.com/c/1fsqa3BtfH1Z…
- Thrilled to share that I’ve been awarded an HHMI Gilliam Fellowship! 😁 Very grateful to the friends, colleagues, and leaders who have helped me get here - especially my advisor Rob Malenka @StanfordPSY and longtime mentor Stephan Lammel @UCBerkeleyNeuro!
- Good morning #SfN2022 ! Come by poster board RR1 this morning to see my PhD project in the Malenka lab: The integration of dopamine and serotonin in the nucleus accumbens gates learning Tues, 8-noon, 483.04 / RR1
- Honored to be a 2024 Weintraub awardee! Many thanks to labmates and mentors in the Malenka and Eshel labs who have taught me so much, and to the excellent scientific communities that helped make the work possible @stanfordneurds & @StanfordBrainA huge congratulations to the recipients of the 2024 @fredhutch @WeintraubAward! These twelve exceptional graduate students exemplify the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub: fredhutch.org/en/news/releas…
- The study I led in the Lammel lab @UCBerkeley is published today @NatureComms ! “Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe” link -> rdcu.be/bT1jS 1/n
- My review article with the Lammel lab is officially in print today! Very happy to share my first publication, “Viral vector strategies for investigating midbrain dopamine circuits underlying motivated behaviors” in Pharmacology, Biochemistry and Behavior: authors.elsevier.com/c/1XxAcKmh4oKLH
- Replying to @dcardozopintoIn sum: 🏁 We uncover a long hypothesized opponent relationship between dopamine & serotonin, and we show that this opponency controls reward and reinforcement. LINK: nature.com/articles/s4158… 9/n
- Out this week @NeuroCellPress, dopamine release encodes sunk costs! Striatal dopamine integrates cost, benefit, and motivation LINK -> sciencedirect.com/science/articl… Led by @NeirEshel
- On my way to Montreal for #Dopamine2022 where I’ll present my PhD work with Rob Malenka for the first time! Stop by poster #2-A-6 on Monday to learn about how “Integration of convergent dopamine and serotonin signals in the Nucleus Accumbens gates Pavlovian learning”
- On my way to #OptoGRC2022 ! Stop by my poster during the Sunday session (GRS) or the Wed/Thu session (GRC) to see my PhD work investigating how “The integration of convergent dopamine and serotonin signals in the Nucleus Accumbens gates Pavlovian learning”
- On my way to Barcelona for the #catecholaminesGRC and thrilled to get to talk about my PhD work in Thursday’s Early Career Investigators session! #GRCcatecholamines
- Here’s a sneak peak into a project I’ve been lucky to work on studying dorsal raphe dynorphin neurons! Led by Matt Pomrenze @mCherryGarcia
