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Geoff Oxnard MD
@geoff_oxnard
Drug & diagnostic developer | Thoracic oncology, Boston Medical Center | Husband, father of 4, splitter of wood | Opinions my own
Boston, MA
coi.asco.org/share/HHV-CHBV…
Joined September 2016
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    Geoff Oxnard MD
    @geoff_oxnard
    Oct 27, 2025
    Fantastic energy this week presenting preliminary findings from our SOLARA trial of BH-30643 in Boston. Please check out the poster which is now on the BHT pipeline website! Study enrolling full steam ahead with a focus on on-target resistance and TKI-naive #EGFR-mutant NSCLC.
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    Geoff Oxnard MD
    @geoff_oxnard
    May 15, 2021
    Oncologists, what's more HOPEFUL than: - caring for a tragically young pt w refractory cancer... - achieving response to investigational tx... - referring him/her back to local doc... - and then stumbling upon him/her years later on TWITTER, now married and thriving?!?
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    Geoff Oxnard MD
    @geoff_oxnard
    Apr 20, 2020
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    Geoff Oxnard MD
    @geoff_oxnard
    May 16, 2019
    Here come 4th generation EGFR inhibitors! New allosteric EGFR inhibitor from Pasi Janne, Nathanial Gray & Michael Eck @DanaFarber, synergistic with osimertinib, just out @CD_AACR. @EGFRResisters #LCSM cancerdiscovery.aacrjournals.org/content/early/…
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    Geoff Oxnard MD
    @geoff_oxnard
    Mar 16, 2023
    Super exciting to work with @genentech on this creative analysis in @NatureMedicine of IMpower150 demonstrating the power of ctDNA monitoring to predict outcome on chemoIO: nature.com/articles/s4159…
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    Geoff Oxnard MD
    @geoff_oxnard
    Jan 17, 2020
    More cool work from the Janne lab @DanaFarber figuring out the vulnerabilities of dormant EGFR-mutant NSCLC on TKI. Inhibiting MEK plus YAP/TEAD tips these surviving cells into apoptosis! cell.com/cancer-cell/fu…
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    Geoff Oxnard MD
    @geoff_oxnard
    Feb 24, 2020
    Nice paper from @MDAndersonNews showing that levels of tumor DNA shed are prognostic. Let's start using liquid biopsies as quantitative tools not just positive/negative! @CCR_AACR clincancerres.aacrjournals.org/content/early/…
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    Geoff Oxnard MD
    @geoff_oxnard
    Feb 4, 2020
    For EGFR resistance, remember to biopsy and test for MET amp! SAVANNAH trial of osimertinib / savolitinib now enrolling globally: thelancet.com/journals/lanon… @LeciaSequist
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    Geoff Oxnard MD
    @geoff_oxnard
    Apr 13, 2022
    So cool to see EGFR C797S being targeted @AACR ! Proud to support a new paradigm of real-time ctDNA response assessment in first-in-human trials - congrats to @ElaineShumMD & @BlueprintMeds:
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    Geoff Oxnard MD
    @geoff_oxnard
    Nov 23, 2021
    Two vaccinated! 💉🩹 The younger two will have to wait. Thank you @challiance! ❤️
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    Geoff Oxnard MD
    @geoff_oxnard
    May 29, 2019
    Our new editorial @CCR_AACR: "Effective cancer genotyping -- many means to one end" clincancerres.aacrjournals.org/content/early/…. A joy to write with Dr. Catherine Meador @BrighamWomens, soon a fellow @DanaFarber! Many tools available so ALL patients can receive effective cancer genotyping.
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    Geoff Oxnard MD
    @geoff_oxnard
    Mar 15, 2019
    Does testing error underlie liquid biopsy discordance? "Bake-off" from @AstraZeneca suggests that, in the wild world of plasma NGS assays, technical factors impact assay variability more than we realize: ascopubs.org/doi/10.1200/PO…
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    Geoff Oxnard MD
    @geoff_oxnard
    Jun 16, 2023
    1/10 I left #ASCO23 last week feeling INSPIRED about the pace of progress & discovery for cancer patients! I'm excited about2⃣ precision oncology themes from the meeting, and it seems others in the oncology community share my excitement:
    dailynews.ascopubs.org
    ASCO Annual Meeting | ASCO Daily News
    The ASCO Annual Meeting is the Society's yearly gathering where oncologists unveil their latest clinical research, and ASCO Daily News has you covered before, during, and after the Meeting with...
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    Geoff Oxnard MD
    @geoff_oxnard
    May 26, 2023
    Super excited for our #ASCO23 ctDNA evidence! 🧬ctDNA monitoring w @BrunaPellini @genentech & @NIVokes @Regeneron 🧬ctDNA tumor fraction w @ChristianRolfo @flatironhealth & @LungMAP 🧬ctDNA fusions w @pashtoonkasi 🧬ctDNA HRRm w @pfizer See you there! foundationmedicine.com//press-release…
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