Sol and Clara Kest Professor, Vice Chair of Research, Site Chair, Director of the Mark Lebwohl Center for Neuroinflammation and Sensation @IcahnMountSinai
I remember Ethan Shevach talking about how he reviewed this paper in @J_Immunol and only accepted it because he thought “why not let this crazy idea through”, though all reviewers were highly skeptical. Not all Nobel Prize papers have to be in glam journals; they likely require a
This year’s medicine laureate Shimon Sakaguchi discovered a new class of T cells.
Sakaguchi was swimming against the tide in 1995, when he made a key discovery. At the time, many researchers were convinced that immune tolerance only developed due to potentially harmful immune
Just reviewed a #paper for a high profile journal and it beautifully integrated multiple concepts we observed in our lab (unpublished) in a way that completely makes sense, explains others' findings, and is incredibly novel. Bravo! ACCEPT with NO revisions. Gladly #scooped.
Hypermobile Ehlers-Danlos and Mast Cell Activation Syndrome are a chicken and the egg scenario that needs clarification and mast cell therapies will greatly inform us better in the near future
BIG NEWS! The Allen Discovery Center for Neuroimmune Interactions with @CellSymposia will co-host the next Neuro-immune axis symposium on September 7-9, 2025 in NYC! Keynotes include @NobelPrize recipient David Julius and @salkinstitute@Tcellogic.
cell-symposia.com/neuroimmunolog…
Many immunologists ask me for a quick primer on neuroimmunology. This review by @keatonsong is a great way to dip your toe in the pool of the greatest biology of the next decade!
If you want your mind blown, you need to read this @Nature article by Rui Chang from @YaleMed. It is both a technical tour de force and a conceptual 🤯. Not exactly lazy Sunday reading.
Submitted our new paper to @Nature which will undergo traditional closed review by volunteer reviewers, posted preprint to @researchsquare for all to see, shared on @ResearchHub for preprint to be reviewed publicly. Our reviewers @ResearchHub will be paid and those reviews will
Sharing experience for junior PI colleagues
Started my lab in 2014, got tenure in 2019
1st R01 got fundable score in 2015 subsequently
5 R01s NOT discussed
2 R01s NOT funded
2 P01s (co-I) NOT funded
1 STTR NOT discussed
Finally 2nd R01 with +fund score last week on A1 🙏😅
So excited to announce I will be joining @IcahnMountSinai Derm @SinaiImmunol@SinaiBrain on 1.1.22 as Vice Chair of Research for Dermatology and Direct an Endowed Center for Neuroinflammation under the leadership of Emma Guttman, @MiriamMerad, @EricJNestler, & Dennis Charney
Unsolicited advice to new PIs and my opinion only not fact:
As a new Assistant Professor, you have a 1-1.5 year window where you can get an R01 without a corresponding author paper IF you have a high impact 1st author paper from your postdoc.
After that, it seems no amount of
The vagus nerve is very important in suppressing systemic inflammation. It sets off a series neurotransmitters along a neuroimmune circuit. Much more to be learned about how many other players are involved and the diversity of diseases impacted. @KevinJTraceyMD@keatonsong