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José R Penadés
@jrpenades
Frustrated football player, I moved to a less relevant work: microbiologist interested on mobile genetic elements
Imperial College
imperial.ac.uk/people/j.penad…
Joined May 2013
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  • user avatar
    José R Penadés
    @jrpenades
    Oct 1, 2021
    Universities sell the idea that their PIs have multiple grants and publish amazing papers. This is bullshit. Getting grants and papers is extremelly difficult, and we are all constantly rejected in academia. From now I'll make public all my rejections, to normalise failure.
  • user avatar
    José R Penadés
    @jrpenades
    Aug 18, 2022
    Thanks to Brexit, I lost a €2.5m research grant. I fear for the future of UK science | José R Penadés
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    Thanks to Brexit, I lost a €2.5m research grant. I fear for the future of UK science | José R...
    From theguardian.com
  • user avatar
    José R Penadés
    @jrpenades
    Apr 7, 2020
    After 7 amazing years in Glasgow, from July I'll start a new job as Director of the @CMBI_Imperial. Half of me really honoured and excited to take on this new an unexpected opportunity. The other half is just terrified!
  • user avatar
    José R Penadés
    @jrpenades
    Nov 8, 2021
    Here it is! I'm not sure chromosomes can be considered MGEs. What is clear is that the transfer of chromosomal genes via lateral transduction is more efficient than the transfer of classical MGEs. Our results raise questions about our definition of MGEs. disq.us/t/42ojt2w
  • user avatar
    José R Penadés
    @jrpenades
    Oct 2, 2021
    More about failure. I arrived Glasgow in 2013. As soon as I arrived, I started putting grants (BBSRC, MRC, WT). I put more than 12 grants until the first one was supported. That occurred two years later. Yes, during this time I thought I was completely useless and incompetent.
  • user avatar
    José R Penadés
    @jrpenades
    May 16, 2024
    I don't think I deserve this, but I am honoured to be elected and very grateful to my family, past and present group members, collaborators, and mentors for making it possible! As a Spaniard, I also thank this country for such extraordinary recognition.
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    royalsociety.org
    Outstanding scientists elected as Fellows of the Royal Society | Royal Society
    Over 90 exceptional researchers from across the world have this year been elected to the Fellowship of the Royal Society.
    28K
  • user avatar
    José R Penadés
    @jrpenades
    Jul 1, 2020
    It is now official! Professor José Penadés appointed as new Director of the MRC CMBI
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    Professor José Penadés appointed as new Director of the MRC CMBI | Imperial News | Imperial College...
    From imperial.ac.uk
  • user avatar
    José R Penadés
    @jrpenades
    Oct 11, 2018
    ...and suddenly, the chromosome become more mobile than most of the classical mobile genetic elements... Genome hypermobility by lateral transduction science.sciencemag.org/content/362/64…
  • user avatar
    José R Penadés
    @jrpenades
    Aug 3, 2023
    We recently discovered lateral transduction (LT). Now, we unveil the 4th mechanism of transduction: lateral cotransduction. This system involves SaPIs and is more powerful and versatile than phage-mediated LT. Great fun with @JchenLab and @jrossfitz
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    Dual pathogenicity island transfer by piggybacking lateral transduction
    From cell.com
    24K
  • user avatar
    José R Penadés
    @jrpenades
    Dec 14, 2021
    Ohhhh... This is really painful. Rejected again from Wellcome Trust. I think this is my 4th consecutive rejection there. I'll try again, that's for sure! But I wanted to share how shit I'm feeling right now. Hope this helps young PIs.
  • user avatar
    José R Penadés
    @jrpenades
    Aug 18, 2022
    Latest from the lab. @AlfredFillol and @jakob_tr deserve all the merit. Here we show that PICIs carry an impressive arsenal of defense systems that block HGT. We also demonstrate that phages benefit from mobilizing these PICIs to target competing MGEs.
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    Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against...
    From cell.com
  • user avatar
    José R Penadés
    @jrpenades
    Sep 13, 2021
    Three layers of parasitism! It was assumed that SaPIs are exclusively induced by helper phages. We report here the remarkable discovery that some SaPIs can instead be induced only by a second, co-resident SaPI, which must first be induced by a phage. nature.com/articles/s4156…
  • user avatar
    José R Penadés
    @jrpenades
    Jun 15, 2021
    Recruting 3-year postdoc funded by @The_MRC to work on Lateral transduction. Join our international lab at @CMBI_Imperial. Please, RT.
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  • user avatar
    José R Penadés
    @jrpenades
    Oct 6, 2021
    With the stars @AlvSanMillan, @CraigMacLean9, @JchenLab, @Suzie_Chapman1 et al., latest from the lab. Plasmids use PICIs and phages to spread in nature. Staphylococcal phages and pathogenicity islands drive plasmid evolution disq.us/t/41qkz0x