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Dr. Len Zon
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Dr. Len Zon
@leonard_zon
Director of the Stem Cell Program @BostonChildrens
Boston, MA
zon.tchlab.org
Joined December 2008
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  • user avatar
    Dr. Len Zon
    @leonard_zon
    Aug 10, 2022
    A dream comes true. Tonight I threw out the first pitch at Fenway for the Red Sox-Braves game. This was in honor of my election to the National Academy of Sciences. Pretty happy with the pitch!😀
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    Dr. Len Zon
    @leonard_zon
    Apr 1, 2021
    The Zon lab is excited to present a method to avoid reformatting of papers with every submission to a new journal. We feel this will save time for scientists. A uniform format for manuscript submission cell.com/cell/fulltext/…
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    Dr. Len Zon
    @leonard_zon
    May 3, 2022
    Honored to be elected to the NAS today. I want to thank all of my lab members whose hard work made this possible, my mentors and my family for all their support over the years.
  • user avatar
    Dr. Len Zon
    @leonard_zon
    Sep 22, 2022
    Very excited to see our new Science paper by my student Sam Wattrus. Macrophages interact with stem cells and determine which clones to selectively amplify or to destroy, providing a quality assurance mechanism for determining which stem cells contribute to adult blood.
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    Dr. Len Zon
    @leonard_zon
    Jun 26, 2022
    Very happy to receive the Christiane Nusslein-Volhard Award today. Presented to me by Liz Patton. The award trophy is so cool - it is a mold of a zebrafish embryo!!
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    Dr. Len Zon
    @leonard_zon
    May 24, 2022
    Very honored to receive the Christiane Nusslein-Volhard Award of the European Zebrafish Society for 2022. Janni (Christiane) and the early Tubingen group was incredibly kind to my lab in collaborating on blood mutants from the major zebrafish screen. ezsociety.org/cnv-awardee-20…
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    Dr. Len Zon
    @leonard_zon
    Sep 13, 2024
    Congrats to my postdoc Cecilia Pessoa Rodrigues on her Science paper. We show that dsRNAs from endogenous viral elements bind to TLR3, inducing the don't eat me signal, B2m, on HSCs. This protects the stem cell from phagocytosis by macrophages.
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    science.org
    Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells
    Macrophages maintain hematopoietic stem cell (HSC) quality by assessing cell surface Calreticulin (Calr), an “eat-me” signal induced by reactive oxygen species (ROS). Using zebrafish genetics, we...
    34K
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    Dr. Len Zon
    @leonard_zon
    Dec 8, 2019
    A great honor to receive the ASH Mentor Award. Thanks to all my trainees and friends.
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    Dr. Len Zon
    @leonard_zon
    Nov 29, 2021
    Excited about the opportunities for cellular barcoding to study stem cell clones and cancer. Great to see some highlights on our recent Science paper.
    nytimes.com
    Stamping Bar Codes on Cells to Solve Medical Mysteries (Published 2021)
    By tracking every cell in an organism, scientists are working out why certain cancer treatments fail, which could lead to improved medicine.
  • user avatar
    Dr. Len Zon
    @leonard_zon
    Jun 15, 2022
    I am attending the 20th International Society for Stem Cell Research (ISSCR) meeting in SF. Hard to believe it has been 20 years since I started the society! It has over 4300 members and is doing a fantastic job at moving the stem cell field forward. Very proud of ISSCR.
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    Dr. Len Zon
    @leonard_zon
    Jul 12, 2019
    Very happy and honored to be selected for this year's American Society of Hematology Mentor Award. hematology.org/Newsroom/Press…
  • user avatar
    Dr. Len Zon
    @leonard_zon
    May 31, 2023
    Congrats to my daughter, Becky, on completing three years of her Oncology Fellowship at Dana-Farber Cancer Institute. Becky is planning on continuing her work in Ben Ebert’s lab and will see patients in Hematology clinic.
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    20K
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    Dr. Len Zon
    @leonard_zon
    Aug 23, 2022
    Very happy and honored to be selected for this year's William Silen Lifetime Achievement in Mentoring Award at Harvard Medical School. It has been a privilege to work with some many talented scientists and doctors through the years. dicp.hms.harvard.edu/awards/excelle…
  • user avatar
    Dr. Len Zon
    @leonard_zon
    May 29, 2024
    I would like to congratulate my daughter, Becky, for receiving this Damon Runyon grant. Very proud of her research!!
    user avatar
    Damon Runyon Cancer Research Foundation
    @DamonRunyon
    May 29, 2024
    Replying to @DamonRunyon
    @beckyzon is working to understand why thalidomide derivatives, a class of drugs used to treat multiple myeloma, increase the likelihood of blood clots for cancer patients. She hopes to translate her findings into more targeted medications that can improve treatment outcomes.
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    25K
  • user avatar
    Dr. Len Zon
    @leonard_zon
    May 29, 2023
    Congrats to my son, Tyler, on graduating from Harvard Business School. We are very very proud of you.
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    23K

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