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Sean Brennan
3,833 posts
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Sean Brennan
@seanwbren
building @regents_sh and @autolaunch_sh Humans: own a slice of an agent's stablecoin profits. Agents: raise via CLI prev. Makerdao, Infura, Bio Protocol
NYC
Joined January 2009
7,502
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  • user avatar
    Sean Brennan
    @seanwbren
    Dec 31, 2024
    AI creates abundance, and the world needs an abundance of science. I’m thrilled to announce I am joining @BioProtocol as the lead for agentic AI, supporting the mission of growing and funding 1000s of BioDAOs. We are currently in the phase of Agents assisting scientists as a
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    Bio Protocol
    @BioProtocol
    Dec 30, 2024
    Imagine 1000s of DeSci DAOs funding science onchain, one for every disease or scientific challenge. For this to work, we need the right infrastructure, automation and models for monetization. BIO is building a protocol for launching and growing BioDAOs. Our goal is to build a
    99K
  • user avatar
    Sean Brennan
    @seanwbren
    Sep 26, 2025
    Today I'm looking back at my preseed startup journey from 2021-23, my time at Bio Protocol starting and growing the AI team, and now what lies ahead with a new project making agent.base.eth at the center. November '21 was my founding of daopanel, a simple control panel for all
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    Linda Xie
    @lindaxie
    Feb 28, 2023
    Relay (@relay_eth) is working on ChatGPT for web3 trained on the project's documentation and powered by @xmtp_. Pretty neat! relay.cc
    22K
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    Sean Brennan
    @seanwbren
    Mar 28, 2025
    agentic science summer
    user avatar
    Bio Protocol
    @BioProtocol
    Mar 27, 2025
    Devs: Come build at the intersection biotech & AI 🧬 Time to bring agentic science to life. 💰 $125K in prizes 🧪 World-class judges from OpenAI, Stanford, Prime Intellect & more 🌐 Fully virtual, with optional in-person events Learn more and apply in the link below ↓
    4.9K
  • user avatar
    Sean Brennan
    @seanwbren
    Nov 6, 2025
    Regent token live. Will become foundational in agent economy. Thank you to all for the belief and support in building with us. Our new discord is the best place for community and talking about onchain tools for agents:
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    Regents
    @regents_sh
    Nov 6, 2025
    CA: 0x6f89bcA4eA5931EdFCB09786267b251DeE752b07 clanker.world/clanker/0x6f89…
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    discord.com
    Join the Regents Discord Server!
    product lab for agent-only economies ⟢ Techtree: Agentic research and publishing platform. Every node is open on IPFS, replicable on marimo.io and distributed on Base.Autolaunch: Agent companies boot
    24K
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    Sean Brennan
    @seanwbren
    Nov 6, 2025
    Token launch tomorrow through @clankeronbase for @regent_cx These have been life the past weeks and excited to see it almost out there
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    8.2K
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    Sean Brennan
    @seanwbren
    Feb 3, 2025
    Replying to @potzkothen123 @bioprotocol and @ChatDKG
    yes we're using @elizaOS and forking the plugin-dkg to work well with converting scientific papers into a 'BioGraph' DKG: docs.origintrail.io/build-with-dkg… $TRAC will be part of it, and $BIO will be staked on agents running on @autonolas' Pearl framework. More details soon!
    15K
  • user avatar
    Sean Brennan
    @seanwbren
    Apr 9, 2025
    excited to open-source this plugin for Eliza. It turns the default agent into a 24/7 task runner, with the Actions to: - analyze papers - add knowledge to a DKG - generate hypotheses from the DKG - judge those hypotheses against a rubric
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    Bio Protocol
    @BioProtocol
    Apr 9, 2025
    Article cover image
    Article
    Announcing the BioAgents elizaOS Plugin: A New Era of Agentic Science in Biotech
    BioAgents elizaOS Plugin is a new open-source tool that brings autonomous AI agents into the heart of scientific research. Built on the elizaOS framework, this plugin can read and reason over...
    2.7K
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    Sean Brennan
    @seanwbren
    Sep 13, 2024
    base'd art
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    1.1K
  • user avatar
    Sean Brennan
    @seanwbren
    Mar 22, 2024
    Think of the AI functioning to absorb pieces of evidence you give it, such as photos shared on Twitter, or dank memecoin memes in groupchats. Then the AI outputs an attestation for you, onchain, that may be very valuable. Follow @0xproofof and read the launch post for more!
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    ensō
    @enso_collective
    Mar 21, 2024
    TL;DR :) We've shifted our focus towards integrating the digital and physical realms, and have begun to develop new initiatives centered around AI & Crypto. ⚡️We're thrilled to announce the launch of our inaugural product, the AI Attestor. paragraph.xyz/@ensocollectiv…
    3.8K
  • user avatar
    Sean Brennan
    @seanwbren
    Oct 30, 2025
    Letdown about the lack of mint today, and going to flip it around. We created 999 cool art cards for early supporters, and I want to get them to everyone who's shown so much interest, support, and friendship over the past days. So instead of buying the NFT to get the
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    2.4K
  • user avatar
    Sean Brennan
    @seanwbren
    May 13, 2025
    “Web2” Scientist Agents are here, now. They are open-source and able to perform consistently at a PhD level. Links in the thread. The demand for them will be incredible, and not just one agent per lab! Hundreds of agents per lab could work on parallelized tasks simultaneously.
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    11K
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    Sean Brennan
    @seanwbren
    Apr 16, 2025
    Speaking May 6th in NYC at Cornell Tech about using agents to build a large DKG from scientific papers. Built on @origin_trail on @base
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    OriginTrail
    @origin_trail
    Apr 16, 2025
    Replying to @origin_trail @KGConference and @Microsoft
    >MEET< @seanwbren – head of agentic science at @BioProtocol. At #DKGcon x @KGConference, he’ll present how BioDAO, powered by @origin_trail DKG, is revolutionizing #DeSci and ushering in a new era of agentic science. 🗽 May 6.
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    2.6K
  • user avatar
    Sean Brennan
    @seanwbren
    Nov 3, 2022
    Today we have the intersection of @xmtp_ encrypted messaging and @LensProtocol social graph. This is huge, and @relay_eth will continue building to be the best way for a site to unlock the potential I wrote about in August mirror.xyz/relaycc.eth/s4… @StaniKulechov @dabit3
  • user avatar
    Sean Brennan
    @seanwbren
    Oct 29, 2025
    friends please engage with this post and I'll DM you. I want everyone to benefit from my new project launching a token early. The @clankeronbase launch is in a week, and a presale at the best FDV is tomorrow.
    3.4K
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