Latest News for: inhibitor

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Insilico Medicine and Hygtia Therapeutics Enter New Global Strategic Collaboration to Co-Develop Novel Brain Penetrant NLRP3 Inhibitor for CNS Diseases treatment

PR Newswire 21 Jan 2026
Through the partnership, the two parties aim to accelerate the global advancement of ISM8969—an orally available, brain penetrant NLRP3 inhibitor for Central Nervous System (CNS) disorders.
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Doctor's weight gain warning to anyone taking GLP-1 inhibitors

The Mirror 20 Jan 2026
These medications "don't magically fix weight loss", he said ... .
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BioAge Announces Indication Expansion for Oral NLRP3 Inhibitor BGE-102, with Plans to Initiate

Image Hastings Tribune 20 Jan 2026
BGE-102 has the potential for therapeutic retinal exposure with oral delivery, reducing treatment burden in ocular indications currently treated with intravitreal therapies ... .
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BioAge Announces Indication Expansion for Oral NLRP3 Inhibitor BGE-102, with Plans to Initiate Phase 1b/2a ...

Nasdaq Globe Newswire 20 Jan 2026
BGE-102 has the potential for therapeutic retinal exposure with oral delivery, reducing treatment burden in ocular indications currently treated with intravitreal therapies ... .
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BioAge announces indication expansion for oral NLRP3 inhibitor BGE-102, with plans to initiate Phase 1b/2a proof-of-concept clinical trial in patients with diabetic macular edema in mid-2026 (Form 8-K) (Bioage Labs Inc)

Public Technologies 20 Jan 2026
BioAge announces indication expansion for oral NLRP3 inhibitor BGE-102, with plans to initiate Phase 1b/2a proof-of-concept clinical trial in patients with diabetic macular edema in mid-2026.
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New FAO guidance on assessing food safety risks related to environmental inhibitors (FAO - Food and Agriculture Organization of the United Nations)

Public Technologies 19 Jan 2026
One of these options involves the use of substances called environmental inhibitors (EIs) that can help mitigate methane emissions from cows and other livestock, and limit the loss of nitrogen from fertilizers used on farms.
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HKU Chemists Develop First-in-Class Inhibitor Targeting a Key Epigenetic Regulator (The University of Hong Kong)

Public Technologies 18 Jan 2026
) Back HKU Chemists Develop First-in-Class Inhibitor Targeting a Key Epigenetic Regulator ... Using structure-guided design, the researchers developed a potent and highly selective inhibitor of YEATS2, named LS-170.
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Brenig Therapeutics Announces Initiation of First-in-Human Study of BT-409, a Brain-Selective NLRP3 Inhibitor, and Provides Update on BT-267, its LRRK2 Program

PR Newswire 15 Jan 2026
The company also provided an update on the continued clinical advancement of BT-267, its highly selective, brain-optimized leucine rich repeat kinase 2 (LRRK2) inhibitor ... Brain-Selective NLRP3 Inhibitor Advancing to First-in-Human Evaluation.
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Korea University Researchers Revive an Abandoned Depression Drug Target Using Structurally Novel NK1 Receptor Inhibitors

PR Newswire 14 Jan 2026
Structurally novel neurokinin-1 receptor inhibitors reduce depressive-like behavior and brain inflammation in mice. SEOUL, South Korea, Jan ... Continue Reading ... Prof ... Several candidates were tested, with compound #15 showing strong activity ... Prof ... 21% ... .
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Whole-genome sequencing may optimize PARP inhibitor use (Cornell University)

Public Technologies 14 Jan 2026
Tumors with this defect are vulnerable to PARP inhibitors, which further disrupt DNA repair, causing cancer cells to accumulate DNA damage and die ... if patients will benefit from PARP inhibitors.
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Cereno Scientific Announces First Peer-Reviewed Publication on HDAC Inhibitor CS014: Antithrombotic Efficacy Without Bleeding Risk Supports Broad Potential in Cardiopulmonary Diseases

PR Newswire 14 Jan 2026
Together, these findings support CS014 as a differentiated and potentially safer HDAC inhibitor with broad therapeutic potential in thrombotic and fibrosis-driven diseases ... our HDAC inhibitor platform.
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