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Flo Chardon
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Flo Chardon

@FloChardon
Scientist and computational biology team lead at the Seattle Hub for Synthetic Biology at the Allen Institute. PhD with @JShendure and @lea_starita.
Seattle, WA
alleninstitute.org/division/seatt…
Joined February 2014
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  • Pinned
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    Flo Chardon
    @FloChardon
    Jul 30, 2023
    I spent my PhD developing novel genomic technologies, and today I am extra excited to share the last bit of this work, which is a multiplex prime editing (PE) screening framework! (1/n)
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    biorxiv.org
    A multiplex, prime editing framework for identifying drug resistance variants at scale
    CRISPR-based genome editing has revolutionized functional genomics, enabling screens in which thousands of perturbations of either gene expression or primary genome sequence can be competitively...
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    Flo Chardon
    @FloChardon
    Oct 18, 2024
    I have only amazing things to say about @sdomcke - her lab will be one of the best out there, both from a scientific and mentorship perspective. I can't wait to visit!
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    Silvia Domcke
    @sdomcke
    Oct 17, 2024
    New synthetic biology / gene regulation lab opening in Zurich! We’re studying how to control cell state transitions – for example, making diseased cells healthy or creating new cellular functions – using systematic perturbations, single-cell genomics and machine learning. 🧵1/4
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    Flo Chardon
    @FloChardon
    Oct 2, 2024
    Exciting times!!!
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    Diego Calderon
    @diegoisworking
    Oct 1, 2024
    Incredibly proud to share that I recently joined @UCSF_BTS @UCSF as an Assistant Professor! This means that the Calderon Lab is now open! Or, more accurately, in the process of opening as I am still unboxing equipment and unraveling giant posters (a last @JSHendure lab gift) 🥳
    Me outside my lab building holding my UCSF badge
    Unraveling a giant poster that says "Calderon Lab est. 2024"
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    Flo Chardon
    @FloChardon
    Oct 2, 2024
    Another phenomenal piece of work from a superstar postdoc and my closest collaborator @TroyMcDiarmid, & incredible (now PhD student!) Megan Taylor! Megan joined the lab as a freshman undergrad, & it has been nothing short of amazing watching her develop into an amazing scientist.
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    Troy McDiarmid
    @TroyMcDiarmid
    Oct 2, 2024
    Beyond stoked to share our latest, entitled “Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording” ! biorxiv.org/content/10.110…
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    Flo Chardon
    @FloChardon
    Sep 19, 2024
    Genomic tech dev is my favorite area of science, and today our paper describing our multiplex CRISPRa screening method to identify cell type specific regulatory elements is published! rdcu.be/dUnoq

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